Myr-Tat-CBD3 (trifluoroacetate salt)
- CAS No.
- Chemical Name:
- Myr-Tat-CBD3 (trifluoroacetate salt)
- Synonyms
- Myr-Tat-CBD3 (trifluoroacetate salt)
- CBNumber:
- CB415532820
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
Myr-Tat-CBD3 (trifluoroacetate salt) price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 37465 | Myr-Tat-CBD3 (trifluoroacetate salt) ≥95% | 1mg | $29 | 2026-04-30 | Buy | |
| Cayman Chemical | 37465 | Myr-Tat-CBD3 (trifluoroacetate salt) ≥95% | 5mg | $128 | 2026-04-30 | Buy | |
| Cayman Chemical | 37465 | Myr-Tat-CBD3 (trifluoroacetate salt) ≥95% | 10mg | $225 | 2026-04-30 | Buy | |
| Cayman Chemical | 37465 | Myr-Tat-CBD3 (trifluoroacetate salt) ≥95% | 25mg | $492 | 2026-04-30 | Buy |
Myr-Tat-CBD3 (trifluoroacetate salt) Chemical Properties, Uses, Production
Description
Myr-Tat-CBD3 is an inhibitor of the protein-protein interaction between the N-type voltage-gated calcium channel Cav2.2 and collapsin response mediator protein 2 (CRMP2).1 It inhibits the Cav2.2-CRMP2 interaction by approximately 81% when used at a concentration of 10 µM and inhibits potassium-induced calcium influx in primary rat dorsal root ganglion (DRG) neurons (IC50 = ~2.8 µM). Myr-Tat-CBD3 (20 µM) inhibits calcium, but not sodium, currents in primary DRG neurons. Intrathecal administration of myr-Tat-CBD3 (20 µg/5 µl) prevents carrageenan-induced decreases in paw withdrawal latencies in rats. Myr-Tat-CBD3 decreases cue-induced reinstatement of cocaine-seeking behavior in rats.2WARNING This product is not for human or veterinary use.
References
[1] LIBERTY FRANÇOIS-MOUTAL. A membrane-delimited N-myristoylated CRMP2 peptide aptamer inhibits CaV2.2 trafficking and reverses inflammatory and postoperative pain behaviors.[J]. PAIN®, 2015, 156 7: 1247-1264. DOI: 10.1097/j.pain.0000000000000147
[2] WILLIAM C BUCHTA. Dynamic CRMP2 Regulation of CaV2.2 in the Prefrontal Cortex Contributes to the Reinstatement of Cocaine Seeking.[J]. Molecular Neurobiology, 2020, 57 1: 346-357. DOI: 10.1007/s12035-019-01711-9
Myr-Tat-CBD3 (trifluoroacetate salt) Preparation Products And Raw materials
Raw materials
Preparation Products
Myr-Tat-CBD3 (trifluoroacetate salt) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Cayman Chemical Company | -- | sales@caymanchem.com | China | 6808 | 58 |
| Neobioscience Co., Ltd. | -- | info@neobioscience.com | CHINA | 6192 | 58 |
| Supplier | Advantage |
|---|---|
| Cayman Chemical Company | 58 |
| Neobioscience Co., Ltd. | 58 |
