Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 4-chloro-

1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 4-chloro-

1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 4-chloro- Structure
1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 4-chloro- structure
CAS No.
918515-16-9
Chemical Name:
1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 4-chloro-
Synonyms
4-Chloro-3-formyl-7-azaindole;4-Chloro-7-azaindole-3-carbaldehyde;4-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde;4-chloro-1H-pyrrolo[2,3-b]pyridine-3-carboxaldehyde;1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 4-chloro-;4-Chloro-3-formyl-7-azaindole/4-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carboxaldehyde
CBNumber:
CB41872055
Molecular Formula:
C8H5ClN2O
Molecular Weight:
180.59
MDL Number:
MFCD09880129
MOL File:
918515-16-9.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:48
Product description Number Pack Size Price
4-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde C422195 500mg $75
4-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde 97% OR927654 1g $95
4-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde 97.0% 4H56-5-D8 250mg $95
4-Chloro-3-formyl-7-azaindole FC16335 1g $110
4-Chloro-3-formyl-7-azaindole FC16335 2g $180
More product size
Request For Quotation

1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 4-chloro- Properties

Density 1.521±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Store in freezer, under -20°C
pka 11.48±0.40(Predicted)
Appearance Light brown to brown Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H335-H332-H312-H315-H319
Precautionary statements  P261-P271-P304+P340-P312-P264-P270-P301+P312-P330-P501-P264-P280-P305+P351+P338-P337+P313P-P280-P302+P352-P312-P322-P363-P501-P264-P280-P302+P352-P321-P332+P313-P362
HS Code  2933998090

1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 4-chloro- price More Price(20)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC C422195 4-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde 918515-16-9 500mg $75 2021-12-16 Buy
Apolloscientific OR927654 4-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde 97% 918515-16-9 1g $95 2021-12-16 Buy
SynQuest Laboratories 4H56-5-D8 4-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde 97.0% 918515-16-9 250mg $95 2021-12-16 Buy
Biosynth Carbosynth FC16335 4-Chloro-3-formyl-7-azaindole 918515-16-9 1g $110 2021-12-16 Buy
Biosynth Carbosynth FC16335 4-Chloro-3-formyl-7-azaindole 918515-16-9 2g $180 2021-12-16 Buy
Product number Packaging Price Buy
C422195 500mg $75 Buy
OR927654 1g $95 Buy
4H56-5-D8 250mg $95 Buy
FC16335 1g $110 Buy
FC16335 2g $180 Buy

1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 4-chloro- Chemical Properties,Uses,Production

Synthesis

1H-Pyrrolo[2,3-b]pyridine, 3-bromo-4-chloro-

1000340-39-5

N,N-Dimethylformamide

68-12-2

1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 4-chloro-

918515-16-9

Step 2: 3-bromo-4-chloro-7-azaindole (8 g, 34.632 mmol) was dissolved in THF (160 mL) and cooled to -78 °C. Under nitrogen protection, n-butyllithium (1.6 M in hexane, 50 mL, 79.63 mmol) was slowly added and stirred for 30 min keeping the temperature at -78 °C. Subsequently, N,N-dimethylformamide (5.056 g, 69.264 mmol) was slowly added and stirring was continued at -78 °C. The reaction mixture was gradually warmed to 25 °C and stirred at this temperature for 2 hours. Upon completion of the reaction, the reaction was quenched by the addition of water (2 mL). The reaction mixture was concentrated under reduced pressure, treated with saturated aqueous ammonium chloride solution (28 mL), the precipitated solid was collected and dried under reduced pressure. Purification by silica gel column chromatography afforded 4-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde (3.5 g, 52% yield) as a light yellow solid. The product was confirmed by 1H NMR (CDCl3): δ 12.6-12.8 (br s, 1H), 10.4-10.6 (s, 1H), 8.26-8.3 (d, 1H), 8.12-8.18 (s, 1H), 7.26-7.3 (d, 1H). The mass spectrum (ESI) showed a molecular ion peak (M+1) of 181, which is consistent with the calculated value of the molecular formula C8H5ClN2O.

References

[1] Patent: WO2008/12635, 2008, A2. Location in patent: Page/Page column 90

1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 4-chloro- Preparation Products And Raw materials

Raw materials

1H-Pyrrolo[2,3-b]pyridine, 3-bromo-4-chloro- N,N-Dimethylformamide Tetrahydrofuran n-Butyllithium

Preparation Products

1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 4-chloro- Suppliers

Global( 94)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		+86-（0）57185586718; +8613336195806 sales@capot.com China 29734 60
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29852 58
Shenzhen Nexconn Pharmatechs Ltd 		+86-755-89396905 +86-15013857715 admin@nexconn.com China 10406 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49975 58
Neostar United (Changzhou) Industrial Co., Ltd. 		+86-0519-85551759 +8613506123987 marketing1@neostarunited.com China 8826 58
ANHUI WITOP BIOTECH CO., LTD 		+8615255079626 eric@witopchemical.com China 23541 58
Hefei Hirisun Pharmatech Co., Ltd 		+8615056975894 shawn@hirisunpharm.com CHINA 9911 58
Dayang Chem (Hangzhou) Co.,Ltd. 		+86-0571-88938639 +8617705817739 info@dycnchem.com China 52846 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
Shenzhen Nexconn Pharmatechs Ltd 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
Neostar United (Changzhou) Industrial Co., Ltd. 		58
ANHUI WITOP BIOTECH CO., LTD 		58
Hefei Hirisun Pharmatech Co., Ltd 		58
Dayang Chem (Hangzhou) Co.,Ltd. 		58

View Lastest Price from 1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 4-chloro- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 4-chloro- pictures 2019-07-06 1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 4-chloro-
918515-16-9
 US $1.00 / kg 1kg 98% 100KG Career Henan Chemical Co

1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 4-chloro- Spectrum

1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 4-chloro-(918515-16-9)1HNMR

918515-16-9(1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 4-chloro-)Related Search:

7-AZAINDOLE-3-CARBOXALDEHYDE 7-Azaindole 1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 4-chloro- 1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid, 4-chloro- 4-Chloro-7-azaindole
1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 4-chloro- 4-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde 4-Chloro-3-formyl-7-azaindole 4-Chloro-7-azaindole-3-carbaldehyde 4-chloro-1H-pyrrolo[2,3-b]pyridine-3-carboxaldehyde 4-Chloro-3-formyl-7-azaindole/4-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carboxaldehyde 918515-16-9 Heterocycle-Pyridine series