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Z-NVA-OH

Z-NVA-OH Structure
Z-NVA-OH structure
CAS No.
21691-44-1
Chemical Name:
Z-NVA-OH
Synonyms
Z-NVA-OH;Cbz-Nva-OH;Z-L-Nva-OH;Z-NORVALINE;Z-APE(2)-OH;CBZ-L-NVA-OH;Z-L-NORVALINE;Z-Nva-OH ,98%;CBZ-L-NORVALINE;Z-L-norvaline99%
CBNumber:
CB4187707
Molecular Formula:
C13H17NO4
Molecular Weight:
251.28
MDL Number:
MFCD00063167
MOL File:
21691-44-1.mol
MSDS File:
SDS
Last updated:2025-07-16 09:53:55
Product description Number Pack Size Price
Z-L-norvaline 285602 10g $363
N-Cbz-L-norvaline 95+% ee AS29383 100g $389
Cbz-L-Norvaline 4158-1-S4 100g $456
N-Cbz-L-norvaline 95+% ee AS29383 5G $57
Z-Nva-OH V4383 100g $602
More product size
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Z-NVA-OH Properties

Boiling point 439.4±38.0 °C(Predicted)
Density 1.184±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,2-8°C
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form Powder
pka 4.00±0.20(Predicted)
Appearance White to off-white Solid
CAS DataBase Reference 21691-44-1(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P271-P261-P280
HS Code  2922498590

Z-NVA-OH price More Price(20)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 285602 Z-L-norvaline 21691-44-1 10g $363 2021-12-16 Buy
Activate Scientific AS29383 N-Cbz-L-norvaline 95+% ee 21691-44-1 100g $389 2021-12-16 Buy
SynQuest Laboratories 4158-1-S4 Cbz-L-Norvaline 21691-44-1 100g $456 2021-12-16 Buy
Activate Scientific AS29383 N-Cbz-L-norvaline 95+% ee 21691-44-1 5G $57 2021-12-16 Buy
AK Scientific V4383 Z-Nva-OH 21691-44-1 100g $602 2021-12-16 Buy
Product number Packaging Price Buy
285602 10g $363 Buy
AS29383 100g $389 Buy
4158-1-S4 100g $456 Buy
AS29383 5G $57 Buy
V4383 100g $602 Buy

Z-NVA-OH Chemical Properties,Uses,Production

Uses

Z-NVA-OH is also known as Cbz-L-norvaline. It could be used to synthesise Z-Nva-Ser(Bu’)-Gly-OPh. In specific steps, as follows: the protected dipeptide(53.1 g. 124mM) and Tos.OH.H2O (33.6g. 124mM) were dissolved in DMF (200) and hydrogenolysed overnight in the presence of 10% Pd/C (6g), then filtered and concentrated to 100ml. Z-Nva-OH (37.4g. 149mM) was dissolved in CH2Cl2 (170ml) and NMM (16.4ml. 149mM) added. After cooling to -20℃, pivaloyl chloride (17.8ml. 145 mM) was added, and the solution was stirred for 20 minutes before the precooled DMF solution from above was added. Following the addition of NMM (13.6 ml, 124 mM), the reaction was stirred at - 20℃ for 3 hr, then maintained at room temperature overnight. The solution was evaporated, and the product dissolved in EtOAc. Washing with acid and base in the usual way, followed by crystallisation from EtOAc/petroleum ether yielded Z-Nva-Ser(Bu’)-Gly-OPh[1].

References

[1] I.J. Galpin. “Peptides—XXXXII.” Tetrahedron 37 17 (1981): Pages 3017-3023.

Z-NVA-OH Preparation Products And Raw materials

Raw materials

Preparation Products

N-ALPHA-BENZYLOXYCARBONYL-N-ALPHA-METHYL-L-NORVALINE

Z-NVA-OH Suppliers

Global( 190)Suppliers
Supplier Tel Email Country ProdList Advantage
Taizhou Tianhong Biochemistry Technology Co., Ltd. 		0523-86132544 sales@thbiochem.com CHINA 305 60
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29821 58
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19552 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49977 58
Neostar United (Changzhou) Industrial Co., Ltd. 		+86-0519-85551759 +8613506123987 marketing1@neostarunited.com China 8828 58
SIMAGCHEM CORP 		+86-5922680277 +86-13806087780 sale@simagchem.com China 17346 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58
Nanjing Fred Technology Co., Ltd. 		+86-02584696168 15380713688 Austin@fredchem.cn CHINA 865 58
Supplier Advantage
Taizhou Tianhong Biochemistry Technology Co., Ltd. 		60
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
BOC Sciences 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
Neostar United (Changzhou) Industrial Co., Ltd. 		58
SIMAGCHEM CORP 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
Nanjing Fred Technology Co., Ltd. 		58

View Lastest Price from Z-NVA-OH manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Z-NVA-OH pictures 2026-04-22 Z-NVA-OH
21691-44-1
 US $0.00 / Kg/Bag 100g 99.0%min 500kgs WUHAN FORTUNA CHEMICAL CO., LTD
Z-NVA-OH pictures 2019-07-06 Z-NVA-OH
21691-44-1
 US $100.00 / KG 1KG 99% Customized Career Henan Chemical Co
  • Z-NVA-OH pictures
  • Z-NVA-OH
    21691-44-1
  • US $0.00 / Kg/Bag
  • 99.0%min
  • WUHAN FORTUNA CHEMICAL CO., LTD
  • Z-NVA-OH pictures
  • Z-NVA-OH
    21691-44-1
  • US $100.00 / KG
  • 99%
  • Career Henan Chemical Co

Z-NVA-OH Spectrum

Z-NVA-OH(21691-44-1)1HNMR

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BENZYLOXYCARBONYL-L-NORVALINE Norvaline reference substance CBZ-L-NORVALINE Z-APE(2)-OH Z-L-ALPHA-AMINOVALERIC ACID Z-L-2-AMINOVALERIC ACID Z-NVA-OH Z-NORVALINE Z-L-NHCH[CH3(CH2)2]-COOH Z-L-NORVALINE RARECHEM AL CF 0968 N-CBZ-L-NORVALINE N-CARBOBENZOXY-L-NORVALINE N-ALPHA-CARBOBENZOXY-L-NORVALINE N-ALPHA-CARBOBENZOXY-L-2-AMINO-PENTANOIC ACID N-ALPHA-CBZ-L-NORVALINE Cbz-Nva-OH NALPHA-Benzyloxycarbonyl-L-norvaline N-alpha-Benzyloxycarbonyl-L-norvaline, (S)-N-alpha-Z-2-amino-valeric acid Z-L-Nva-OH Z-L-NORVALINE extrapure N-Carbobenzoxy-DL-norvaline N-Cbz-DL-norvaline Z-Nva-OH ,98% Z-L-a-aMinovaleric acid (2S)-2-{[(benzyloxy)carbonyl]aMino}pentanoic acid L-Norvaline, N-[(phenylmethoxy)carbonyl]- Z-L-norvaline99% (2S)-2-(phenylmethoxycarbonylamino)pentanoic acid 2-(phenylmethoxycarbonylamino)pentanoic acid Valacyclovir Impurity 5 Valacyclovir Impurity 5 (N-Cbz-L-Norvaline) Valacyclovir Impurity 26 (2S)-2-(phenylmethoxycarbonylamino)pentanoicaci Z-NVA-OH USP/EP/BP CBZ-L-NVA-OH Diethylcarbamazine Impurity 2（Diethylcarbamazine EP Impurity B） 21691-44-1 Peptide