2-Methoxypyrazine
- CAS No.
- 3149-28-8
- Chemical Name:
- 2-Methoxypyrazine
- Synonyms
- METHOXYPYRAZINE;Pyrazine, methoxy-;FEMA 3302;methoxy-pyrazin;FEMA NUMBER 3302;2-METHOXYPYRAZINE;Methoxypyrazine,98%;METHOXYPYRAZINE, 2-;Pyrazine, 2-Methoxy-;2-Methoxypyrazine>
- CBNumber:
- CB4202646
- Molecular Formula:
- C5H6N2O
- Molecular Weight:
- 110.11
- MDL Number:
- MFCD00006126
- MOL File:
- 3149-28-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 2-Methoxypyrazine ≥99%, FCC, FG | W330205 | 1kg | $1120 |
| 2-Methoxypyrazine 95% | 291420 | 5g | $33 |
| 2-Methoxypyrazine ≥99%, FCC, FG | W330205 | sample-k | $53.8 |
| 2-Methoxypyrazine ≥99%, FCC, FG | W330205 | 25g | $102 |
| 2-Methoxypyrazine ≥99%, FCC, FG | W330205 | 100g | $166 |
| More product size | |||
| Boiling point | 60-61 °C/29 mmHg (lit.) |
|---|---|
| Density | 1.14 g/mL at 25 °C (lit.) |
| refractive index |
n |
| FEMA | 3302 | METHOXYPYRAZINE |
| FLAVIS Number | 14.054 | Methoxypyrazine |
| Flash point | 114 °F |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 0.53±0.10(Predicted) |
| form | clear liquid |
| color | Colorless to Almost colorless |
| Specific Gravity | 1.140 |
| Odor | at 1.00 % in dipropylene glycol. sweet nutty cocoa |
| Odor Type | chocolate |
| JECFA Number | 787 |
| BRN | 2241 |
| InChI | 1S/C5H6N2O/c1-8-5-4-6-2-3-7-5/h2-4H,1H3 |
| InChIKey | WKSXRWSOSLGSTN-UHFFFAOYSA-N |
| SMILES | COc1cnccn1 |
| LogP | 0.75 |
| CAS DataBase Reference | 3149-28-8(CAS DataBase Reference) |
| Substances Added to Food (formerly EAFUS) | METHOXYPYRAZINE |
| EWG's Food Scores | 1 |
| FDA UNII | RYD35T7F4T |
| NIST Chemistry Reference | Pyrazine, methoxy-(3149-28-8) |
| EPA Substance Registry System | Pyrazine, methoxy- (3149-28-8) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() ![]() ![]() GHS02,GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H226-H302-H315-H318-H335 | |||||||||
| Precautionary statements | P261-P280-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 10-22-37/38-41 | |||||||||
| Safety Statements | 16-26-39 | |||||||||
| RIDADR | UN 1993 3/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 3 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29339990 | |||||||||
| Storage Class | 3 - Flammable liquids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Eye Dam. 1 Flam. Liq. 3 Skin Irrit. 2 STOT SE 3 |
|||||||||
| Limited Quantities | 5.0 L (1.3 gallons) (liquid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) | |||||||||
| NFPA 704 |
|
2-Methoxypyrazine price More Price(60)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | W330205 | 2-Methoxypyrazine ≥99%, FCC, FG | 3149-28-8 | 1kg | $1120 | 2023-01-07 | Buy |
| Sigma-Aldrich | 291420 | 2-Methoxypyrazine 95% | 3149-28-8 | 5g | $33 | 2023-01-07 | Buy |
| Sigma-Aldrich | W330205 | 2-Methoxypyrazine ≥99%, FCC, FG | 3149-28-8 | sample-k | $53.8 | 2022-05-15 | Buy |
| Sigma-Aldrich | W330205 | 2-Methoxypyrazine ≥99%, FCC, FG | 3149-28-8 | 25g | $102 | 2022-05-15 | Buy |
| Sigma-Aldrich | W330205 | 2-Methoxypyrazine ≥99%, FCC, FG | 3149-28-8 | 100g | $166 | 2022-05-15 | Buy |
2-Methoxypyrazine Chemical Properties,Uses,Production
Description
2-methoxypyrazine is a kind of pyrazine derivative. It emits a kernels and cocoa-like aroma. It is a commonly used daily, food flavoring agent. It has many kinds of flavoring derivatives such as 3-Isobutyl-2-methoxypyrazine, 3-sec-butyl-2-methoxypyrazine, 3-alkyl-2-methoxypyrazines and 3-isopropyl-2-methoxypyrazine. There derivatives could be found in wine and many kinds of fruits such as berry and grapes.
References
Murray, K. E., J. Shipton, and F. B. Whitfield. "2-methoxypyrazines and the flavour of green peas (Pisum sativum). " Chemistry & Industry 27.14(1970):897-898.
Hashizume, Katsumi, and Takashi Samuta. "Grape maturity and light exposure affect berry methoxypyrazine concentration." American Journal of Enology and Viticulture 50.2 (1999): 194-198.
Hartmann, Peter J., Harold M. McNair, and Bruce W. Zoecklein. "Measurement of 3-alkyl-2-methoxypyrazine by headspace solid-phase microextraction in spiked model wines." American Journal of Enology and Viticulture 53.4 (2002): 285-288.
HASHiZUME, Katsumi, and Norihiko Umeda. "Methoxypyrazine content of Japanese red wines." Bioscience, biotechnology, and biochemistry 60.5 (1996): 802-805.
Lacey, Michael J., et al. "Methoxypyrazines in Sauvignon blanc grapes and wines." American Journal of Enology and Viticulture 42.2 (1991): 103-108.
Description
Methoxypyrazine has an odor threshold of 700 ppb in water. Methoxypyrazine may be prepared from 2-hydroxypyrazine by various routes.
Chemical Properties
Methoxypyrazine has a sweet, nutty, cocoa odor. Methoxypyrazine contributes a distinctive “green, capsicum (bell pepper), herbaceous and earthy” aroma that is quite characteristic of certain wines, such as sauvignon blanc and cabernet sauvignon.
Chemical Properties
Colorless liquid
Occurrence
Present at ultra-trace levels in sauvignon blanc and cabernet sauvignon grapes and wine. Methoxypyrazine contributes a distinctive wine aroma, even at low parts per trillion levels. Also reported found in cooked beef, cocoa, malt and krill.
Definition
ChEBI: Methoxypyrazine is an aromatic ether and a member of pyrazines.
Preparation
From 2-hydroxypyrazine by various routes.
Aroma threshold values
700 ppb in water
Safety Profile
Skin and eye irritant. When heated to decomposition it emits toxic fumes of NOx.
2-Methoxypyrazine Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +86-15350571055 | Sibel@chuanghaibio.com | China | 8737 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 | sales1@chuanghaibio.com | China | 5216 | 58 |
| Henan Bao Enluo International TradeCo.,LTD | +86-17331933971 | deasea125996@gmail.com | China | 2452 | 58 |
| JINING XINHE CHEMICAL CO., LTD | +8615318402391 | sales@xinhepharma.com | China | 808 | 58 |
| Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 | niki@zlchemi.com | China | 7240 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21531 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32998 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29766 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2949 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 | sales@amoychem.com | China | 6339 | 58 |
View Lastest Price from 2-Methoxypyrazine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-06-30 | 2-Methoxypyrazine
3149-28-8
|
1KG | 98.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | ||
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2026-05-28 | 2-Methoxypyrazine
3149-28-8
|
$2.00-5.00 | 1KG | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD | |
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2026-04-22 | 2-Methoxypyrazine
3149-28-8
|
$29.00 | 99.94% | 10g | TargetMol Chemicals Inc. |
-

- 2-Methoxypyrazine
3149-28-8
- 98.0%
- Shaanxi Dideu New Materials Co. Ltd
-

- 2-Methoxypyrazine
3149-28-8
- $2.00-5.00
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
-

- 2-Methoxypyrazine
3149-28-8
- $29.00
- 99.94%
- TargetMol Chemicals Inc.
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