Anti-PFN2
- CAS No.
- Chemical Name:
- Anti-PFN2
- Synonyms
- Anti-PFN2;Anti-Profilin 2 (C-terminal) antibody produced in rabbit
- CBNumber:
- CB42101231
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
| Product description | Number | Pack Size | Price |
| Anti-Profilin 2 (C-terminal) antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution | P0101 | 200μL | $272.5 |
SAFETY
Risk and Safety Statements
| PPE | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
|---|---|
| WGK Germany | WGK 2 |
| Storage Class | 10 - Combustible liquids |
Anti-PFN2 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | P0101 | Anti-Profilin 2 (C-terminal) antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution | 200μL | $272.5 | 2025-07-31 | Buy |
| Product number | Packaging | Price | Buy |
|---|---|---|---|
| P0101 | 200μL | $272.5 | Buy |
Anti-PFN2 Chemical Properties,Uses,Production
Uses
Anti-Profilin 2 (C-terminal) antibody produced in rabbit has been used in immunostaining and immunoblotting.
Biological Activity
Profilins are key regulators of actin dynamics. Profilin 2 (PFN2) associates with a number of proteins involved in membrane trafficking and endocytosis, such as synapsin and dynamin 1. It associates with dynamin 1 through the C-terminal proline-rich domain of dynamin 1 and thereby competes with the binding of SH3 ligands, such as endophilin and amphiphysin, thus interfering with the assembly of the endocytic machinery. Overexpression of profilin 2 inhibits endocytosis. Absence of profilin 2 in neurons increases endocytosis and membrane recycling. Profilin 2 is required for stimulated actin polymerization in the synapse and is involved in the regulation of synaptic vesicle exocytosis, neuronal excitability and complex behavior.
Anti-PFN2 Preparation Products And Raw materials
Raw materials
Preparation Products
Anti-PFN2 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Atlas antibodies | 46-854595850 | order@atlasantibodies.com | China | 6586 | 58 |
| Merck KGaA | 21-20338288 | ordercn@merckgroup.com | China | 6394 | 58 |
| Supplier | Advantage |
|---|---|
| Atlas antibodies | 58 |
| Merck KGaA | 58 |
