3-Methoxyphenylboronic acid
- CAS No.
- 10365-98-7
- Chemical Name:
- 3-Methoxyphenylboronic acid
- Synonyms
- AKOS BRN-0015;3-boronoanisole;RARECHEM AH PB 0180;3-Methoxyphenylboron;M-Anisylboronic Acid;M-METHOXY PHENYLBORIC;3-Methoxyphenylboronic;Anisole-3-boronic acid;3 Anisole Boronic Acid;3-Methoxyphenylboric acid
- CBNumber:
- CB4212548
- Molecular Formula:
- C7H9BO3
- Molecular Weight:
- 151.96
- MDL Number:
- MFCD00161359
- MOL File:
- 10365-98-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 160-163 °C (lit.) |
|---|---|
| Boiling point | 318.6±44.0 °C(Predicted) |
| Density | 1.17±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 8.10±0.10(Predicted) |
| form | Crystalline Powder |
| color | White to light beige |
| BRN | 2831223 |
| InChI | InChI=1S/C7H9BO3/c1-11-7-4-2-3-6(5-7)8(9)10/h2-5,9-10H,1H3 |
| InChIKey | NLLGFYPSWCMUIV-UHFFFAOYSA-N |
| SMILES | B(C1=CC=CC(OC)=C1)(O)O |
| CAS DataBase Reference | 10365-98-7(CAS DataBase Reference) |
| FDA UNII | T4XV2NE6NL |
| UNSPSC Code | 12352103 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P270-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 22-36/37/38 | |||||||||
| Safety Statements | 26-36-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29319090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
3-Methoxyphenylboronic acid price More Price(76)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 441686 | 3-Methoxyphenylboronic acid | 10365-98-7 | 1g | $65.2 | 2026-04-30 | Buy |
| Sigma-Aldrich | 441686 | 3-Methoxyphenylboronic acid | 10365-98-7 | 10g | $175 | 2023-06-20 | Buy |
| TCI Chemical | M1322 | 3-Methoxyphenylboronic Acid (contains varying amounts of Anhydride) | 10365-98-7 | 1g | $17 | 2026-04-30 | Buy |
| TCI Chemical | M1322 | 3-Methoxyphenylboronic Acid (contains varying amounts of Anhydride) | 10365-98-7 | 5g | $37 | 2026-04-30 | Buy |
| Usbiological | 284528 | 3-Methoxyphenylboronic acid Asreported | 10365-98-7 | 50g | $206 | 2026-06-03 | Buy |
3-Methoxyphenylboronic acid Chemical Properties, Uses, Production
Chemical Properties
3-Methoxyphenylboronic acid is a white to light yellow crystal powder, irritating.
Uses
suzuki reaction
Uses
3-Methoxyphenylboronic Acid is a phenylboronic acid used to investigate boron function in plants.
Synthesis
2398-37-0
121-43-7
10365-98-7
Phase I: Synthesis of 3-methoxyphenylboronic acid 1. 41.3 g (220 mmol) of m-bromoanisole was dissolved in 880 mL of tetrahydrofuran under nitrogen protection and the solution was cooled to -70 °C in an ethanol/dry ice cooling bath. 2. 160 mL (250 mmol) of butyllithium solution (1.6 M in hexane) was added slowly dropwise, with the rate of acceleration of the drop being controlled to ensure that the reaction temperature did not exceed -60 °C. 3. After stirring the reaction mixture continuously for 1.5 hours at -70 °C, slowly add 75 mL (660 mmol) of trimethyl borate dropwise, again controlling the temperature to not exceed -60 °C. 4. 4. After the dropwise addition, the reaction mixture was continued to be stirred for 1 hour under cooling conditions. 5. The reaction mixture was slowly warmed to 25 °C over a period of 2 hours, followed by the addition of 720 mL of 1 M hydrochloric acid and stirring at 25 °C for 15 hours. 6. Upon completion of the reaction, post-treatment was performed: the reaction mixture was extracted with 300 mL of ether, repeated three times, and the organic phases were combined. 7. The combined organic phases were washed sequentially with 100 mL of water and saturated sodium chloride solution, then dried with anhydrous magnesium sulfate and filtered. 8. The filtrate was concentrated on a rotary evaporator (pressure controlled at 500-10 mbar) to give 30.8 g of 3-methoxyphenylboronic acid in 92.1% yield of the theoretical value.
References
[1] Patent: US2002/198251, 2002, A1
[2] Tetrahedron Letters, 2012, vol. 53, # 46, p. 6182 - 6185,4
[3] Journal of the Chemical Society - Perkin Transactions 1, 1999, # 17, p. 2513 - 2523
[4] Bioorganic and Medicinal Chemistry Letters, 2017, vol. 27, # 9, p. 1919 - 1922
3-Methoxyphenylboronic acid Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
1of2
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Tianjin Xinshengjiahe Technology Development Co., Ltd. | 022-83719186 13212251377 | 18522618860@163.com | China | 82 | 55 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44852 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
Related articles
- 3-Methoxyphenylboronic Acid in Organic Synthesis
- 3-Methoxyphenylboronic acid is a key arylboronic acid for Suzuki-Miyaura coupling, enabling synthesis of diaryl structures and....
- Jan 20,2026
View Latest Price from 3-Methoxyphenylboronic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-02 | 3-Methoxyphenylboronic acid
10365-98-7
|
$1.20-34.00 | 1kg | 99% | Henan Fengda Chemical Co., Ltd | ||
 |
2025-07-29 | 3-Methoxyphenylboronic acid
10365-98-7
|
$6.00 | 1kg | 99% | 2000KG/Month | HebeiShuoshengImportandExportco.,Ltd | |
 |
2025-03-28 | 3-Methoxyphenylboronic acid
10365-98-7
|
$7.00 | 1KG | 99% | 20TONS | Hebei Longbang Technology Co., Ltd |
-
- 3-Methoxyphenylboronic acid
10365-98-7
- $1.20-34.00
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 3-Methoxyphenylboronic acid
10365-98-7
- $6.00
- 99%
- HebeiShuoshengImportandExportco.,Ltd
-
- 3-Methoxyphenylboronic acid
10365-98-7
- $7.00
- 99%
- Hebei Longbang Technology Co., Ltd
