1-PHENYL-3-(2-THIAZOLYL)-2-THIOUREA
- CAS No.
- 14901-16-7
- Chemical Name:
- 1-PHENYL-3-(2-THIAZOLYL)-2-THIOUREA
- Synonyms
- U-14624;phenylthiazolylthiourea;n-phenyl-n’-2-thiazolyl-thioure;1-Phenyl-3-(2-thiazolyl)thiourea;1-PHENYL-3-(THIAZOL-2-YL)THIOUREA;N-Phenyl-N'-(2-thiazolyl)thiourea;N-Phenyl-N'-(thiazol-2-yl)thiourea;Thiourea, N-phenyl-N'-2-thiazolyl-;1-phenyl-3-(2-thiazole)-2-thiourea;1-phenyl-3-(2-thiazolyl)-2-thio-ure
- CBNumber:
- CB4215064
- Molecular Formula:
- C10H9N3S2
- Molecular Weight:
- 235.33
- MDL Number:
- MFCD00005321
- MOL File:
- 14901-16-7.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 1-PHENYL-3-(2-THIAZOLYL)-2-THIOUREA 95.00% | CHM0006993 | 5MG | $503.56 |
| 1-Phenyl-3-(thiazol-2-yl)thiourea >90% | AA007J8J | 500mg | $626 |
| 1-Phenyl-3-(thiazol-2-yl)thiourea >90% | AA007J8J | 1mg | $152 |
| 1-Phenyl-3-(thiazol-2-yl)thiourea >90% | AA007J8J | 5mg | $163 |
| 1-Phenyl-3-(thiazol-2-yl)thiourea >90% | AA007J8J | 10mg | $187 |
| Melting point | 183-185 °C (dec.)(lit.) |
|---|---|
| Density | 1.3479 (rough estimate) |
| refractive index | 1.5500 (estimate) |
| form | Solid |
| color | Off-white to yellow |
| CAS DataBase Reference | 14901-16-7(CAS DataBase Reference) |
| FDA UNII | YLB873BH59 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|---|---|
| Signal word | Danger |
| Hazard statements | H318-H335-H302-H315 |
| Precautionary statements | P280-P305+P351+P338-P310-P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362 |
| Hazard Codes | Xn |
| Risk Statements | 22-37/38-41 |
| Safety Statements | 26-39 |
| WGK Germany | 3 |
| RTECS | YU1398000 |
1-PHENYL-3-(2-THIAZOLYL)-2-THIOUREA price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | CHM0006993 | 1-PHENYL-3-(2-THIAZOLYL)-2-THIOUREA 95.00% | 14901-16-7 | 5MG | $503.56 | 2021-12-16 | Buy |
| aablocks | AA007J8J | 1-Phenyl-3-(thiazol-2-yl)thiourea >90% | 14901-16-7 | 500mg | $626 | 2021-12-16 | Buy |
| aablocks | AA007J8J | 1-Phenyl-3-(thiazol-2-yl)thiourea >90% | 14901-16-7 | 1mg | $152 | 2021-12-16 | Buy |
| aablocks | AA007J8J | 1-Phenyl-3-(thiazol-2-yl)thiourea >90% | 14901-16-7 | 5mg | $163 | 2021-12-16 | Buy |
| aablocks | AA007J8J | 1-Phenyl-3-(thiazol-2-yl)thiourea >90% | 14901-16-7 | 10mg | $187 | 2021-12-16 | Buy |
1-PHENYL-3-(2-THIAZOLYL)-2-THIOUREA Chemical Properties,Uses,Production
Chemical Properties
light brown fine crystalline powder
Uses
U-14624 is a potent and orally active dopamine beta-hydroxylase inhibitor. U-14624 suppresses the activities of aminopyrine N-demethylase, aniline hydroxylase and p-nitroanisole O-demethylase enzymes[1][2].
in vivo
U-14624 (50 mg/kg; i.p.; daily for 5-7 days) suppresses the activities of aminopyrine N-demethylase, aniline hydroxylase and p-nitroanisole O-demethylase enzymes in rats[2].
| Animal Model: | 150-260 g, Male Sprague-Dawley rats[2] |
| Dosage: | 25 mg/kg |
| Administration: | I.p.; daily for 3 days |
| Result: | Prolonged the time required for clearance of pentobarbital from both the plasma and brain, slept significantly longer. |
| Animal Model: | 150-260 g, Male Sprague-Dawley rats[2] |
| Dosage: | 50 mg/kg |
| Administration: | I.p.; daily for 5-7 days |
| Result: | Suppressed the activities of aminopyrine N-demethylase, aniline hydroxylase and p-nitroanisole O-demethylase enzymes. |
References
[1] Von Voigtlander PF, et al. Behavioral and brain catecholamine depleting actions of U-14,624, an inhibitor of dopamine beta-hydroxylase. Proc Soc Exp Biol Med. 1970 Mar;133(3):817-20. DOI:10.3181/00379727-133-34571
[2] Smith JR, et al. Effect of the catecholamine-depleting agent 1-phenyl-3-(2-thiazolyl)-2-thiourea (U-14,624) on drug metabolism in the rat. Biochem Pharmacol. 1980 Sep 15;29(18):2425-30. DOI:10.1016/0006-2952(80)90345-7
1-PHENYL-3-(2-THIAZOLYL)-2-THIOUREA Preparation Products And Raw materials
Raw materials
Preparation Products
1-PHENYL-3-(2-THIAZOLYL)-2-THIOUREA Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 19960 | 58 |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53803 | 58 |
| NANJING YINGWEN BIOTECHNOLOGY CO LTD | +8613382787392 | sales@aeechem.com | China | 10000 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Mainchem Co., Ltd. | +86-0592-6210733 | sale@mainchem.com | China | 32343 | 55 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40228 | 62 |
| Hunan Hui Bai Shi Biotechnology Co., Ltd. | 0731-85526065 13308475853 | ivy@hnhbsj.com | China | 7245 | 62 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 71615 | 60 |
| Shanghai Rechem science Co., Ltd. | 021-31433387 15618786686 | sales@rechemscience.com | China | 2963 | 58 |
View Lastest Price from 1-PHENYL-3-(2-THIAZOLYL)-2-THIOUREA manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-03-12 | Phenylthiazolylthiourea
14901-16-7
|
US $1980.00-2500.00 / mg | 10g | TargetMol Chemicals Inc. |
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- Phenylthiazolylthiourea
14901-16-7
- US $1980.00-2500.00 / mg
- TargetMol Chemicals Inc.
