ChemicalBook >> CAS DataBase List >>Pilocarpine nitrate

Pilocarpine nitrate

CAS No.
148-72-1
Chemical Name:
Pilocarpine nitrate
Synonyms
Nitrat;Pilocarpine nitrate for system suitability CRS;Pilagan;pilofrin;Pilocarpinnitrat;Einecs 205-723-7;Pilocarpin Nitrate;Pilocarpini nitras;PILOCARPINE NITRATE;p.v.carpineliquifilm
CBNumber:
CB4237796
Molecular Formula:
C11H17N3O5
Molecular Weight:
271.27
MDL Number:
MFCD00078497
MOL File:
148-72-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-22 18:57:36
Product description Number Pack Size Price
Pilocarpine nitrate for system suitability European Pharmacopoeia (EP) Reference Standard Y0000106 20 mg $167
Pilocarpine nitrate European Pharmacopoeia (EP) Reference Standard P1700000 50 mg $127
Pilocarpine nitrate meets USP testing specifications P0597 5g $500
Pilocarpine nitrate meets USP testing specifications P0597 25g $1730
Pilocarpine nitrate British Pharmacopoeia (BP) Reference Standard BP503 200MG $223
More product size

Pilocarpine nitrate Properties

Melting point 173,5-174°C
alpha D +77 to +83° (c = 10)
refractive index 81 ° (C=2, H2O)
storage temp. 2-8°C
solubility H2O: 0.1 g/mL, clear, very faintly yellow
form powder
color white
optical activity [α]25/D +83°, c = 10 in H2O(lit.)
Water Solubility H2O: 100mg/mL
Merck 14,7424
BRN 4171406
Major Application pharmaceutical (small molecule)
InChI 1S/C11H16N2O2.HNO3/c1-3-10-8(6-15-11(10)14)4-9-5-12-7-13(9)2;2-1(3)4/h5,7-8,10H,3-4,6H2,1-2H3;(H,2,3,4)/t8-,10-;/m0./s1
InChIKey PRZXEPJJHQYOGF-GNAZCLTHSA-N
SMILES O[N+]([O-])=O.CC[C@H]1[C@H](COC1=O)Cc2cncn2C
CAS DataBase Reference 148-72-1(CAS DataBase Reference)
FDA UNII M20T465H6J
EPA Substance Registry System Pilocarpine nitrate (148-72-1)
UNSPSC Code 12352200
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS03,GHS06
Signal word  Danger
Hazard statements  H272-H302-H330
Precautionary statements  P210-P220-P260-P264-P301+P312-P304+P340+P310
PPE Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Hazard Codes  Xn,T+
Risk Statements  22-26/28
Safety Statements  1-25-45
RIDADR  3087
WGK Germany  3
RTECS  TK1455000
3-10
TSCA  TSCA listed
HazardClass  6.1(b)
PackingGroup  III
HS Code  2939800000
Storage Class 5.1B - Oxidizing hazardous materials
Hazard Classifications Acute Tox. 2 Inhalation
Acute Tox. 4 Oral
Ox. Sol. 2
Toxicity LD50 oral in rat: 911mg/kg

Pilocarpine nitrate price More Price(20)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich Y0000106 Pilocarpine nitrate for system suitability European Pharmacopoeia (EP) Reference Standard 148-72-1 20 mg $167 2026-03-19 Buy
Sigma-Aldrich P1700000 Pilocarpine nitrate European Pharmacopoeia (EP) Reference Standard 148-72-1 50 mg $127 2026-03-19 Buy
Sigma-Aldrich P0597 Pilocarpine nitrate meets USP testing specifications 148-72-1 5g $500 2026-03-19 Buy
Sigma-Aldrich P0597 Pilocarpine nitrate meets USP testing specifications 148-72-1 25g $1730 2026-03-19 Buy
Sigma-Aldrich BP503 Pilocarpine nitrate British Pharmacopoeia (BP) Reference Standard 148-72-1 200MG $223 2026-03-19 Buy
Product number Packaging Price Buy
Y0000106 20 mg $167 Buy
P1700000 50 mg $127 Buy
P0597 5g $500 Buy
P0597 25g $1730 Buy
BP503 200MG $223 Buy

Pilocarpine nitrate Chemical Properties,Uses,Production

Chemical Properties

White or almost white, crystalline powder or colourless crystals, sensitive to light.

Uses

antiglaucoma agent, miotic

Uses

Antiglaucoma drug;Cholinergic

Uses

Pilocarpine nitrate salt has been used to measure bronchoconstriction and M2 and M3 muscarinic receptor function in vivo. It has also been used to induce electrographic and behavioral seizures and to study the different patterns of neuronal activation and neurodegeneration in Proechimys rats and Wistar rats.

brand name

Pilagan (Allergan).

General Description

Pilocarpine mononitrate occursas shining white crystals that are not hygroscopic butare light sensitive. It is soluble in water (1:4) and alcohol(1:75) but insoluble in chloroform and ether. Aqueoussolutions are slightly acid to litmus and may be sterilizedin the autoclave. The alkaloid is incompatible with alkalies,iodides, silver nitrate, and reagents that precipitatealkaloids.

Biochem/physiol Actions

Pilocarpine is a cholinergic muscarinic agonist, useful in inducing epilepsy in animal models. It is specially used to study the pathogenesis of epileptogenesis and pharmacoresistant epilepsy. Pilocarpine application is more popular among the rat and mice models.

Pilocarpine nitrate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 146)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652 info@fdachem.com China 20124 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21591 55
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49977 58
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32467 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6312 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250 1026@dideu.com China 18895 58
AFINE CHEMICALS LIMITED
+86-0571-85134551 sales@afinechem.com China 15080 58
Dayang Chem (Hangzhou) Co.,Ltd.
+86-0571-88938639 +8617705817739 info@dycnchem.com China 52705 58
TargetMol Chemicals Inc.
+1-781-999-5354; support@targetmol.com United States 39040 58
GIHI CHEMICALS CO.,LIMITED
+86-571-86217390; +8618058761490 info@gihichemicals.com China 49968 58

View Lastest Price from Pilocarpine nitrate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Pilocarpine nitrate pictures 2026-04-22 Pilocarpine nitrate
148-72-1
US $92.00 / mg 98.00% 10g TargetMol Chemicals Inc.
Pilocarpine nitrate pictures 2026-04-22 Pilocarpine nitrate
148-72-1
US $92.00 / mg 98.00% 10g TargetMol Chemicals Inc.
Pilocarpine nitrate USP/EP/BP pictures 2025-11-18 Pilocarpine nitrate USP/EP/BP
148-72-1
US $1.10 / g 1g 99.9% 100 Tons min Dideu Industries Group Limited
3-ETHYLDIHYDRO-4-[(1-METHYL-1H-IMIDAZOL-5-YL)-METHYL]-2-(3H)-FURANONE NITRATE 2(3H)-Furanone, 3-ethyldihydro-4-(1-methyl-1H-imidazol-5-yl)methyl-, (3S,4R)-, mononitrate PILOCARPINENITRATE,CRYSTAL,USP Pilagan Pilocarpinnitrat (3S)-3-Ethyl-4-[(3-methylimidazol-4-yl)methyl]oxolan-2-one nitrate (3S,4R)-3-Ethyldihydro-4-((1-methyl-1H-imidazol-5-yl)methyl)-2(3H)-furanone mononitrate Pilocarpini nitras (3S,4R)-3-ethyl-4-((1-Methyl-1H-iMidazol-5-yl)Methyl)dihydrofuran-2(3H)-one nitrate 2(3H)-Furanone, 3-ethyldihydro-4-((1-methyl-1H-imidazol-5-yl)methyl)-, (3S,4R)-, nitrate (1:1) 2(3H)-Furanone, 3-ethyldihydro-4-((1-methyl-1H-imidazol-5-yl)methyl)-, (3S-cis)-, mononitrate Einecs 205-723-7 Pilocarpine Nitrate (200 mg) Pilocarpin Nitrate PILOCARPINE NITRATE, PH EUR Nitrat Pilocarpine Nitrate Impurity Ⅰ:(3R,4R)-3-ethyl-4-((1-Methyl-1H-iMidazol-5-yl)Methyl)dihydrofuran-2(3H)-one nitrate PILOCARPINE NITRATE PILOCARPINE NITRATE SALT 3-ethyldihydro-4-[(1-methyl-1h-imidazol-5-yl)methyl]-2(3h)-furanon(3s-cis) p.v.carpineliquifilm pilocarpine,mononitrate Pilocarpinenitrateusp pilocarpinesubnitrate pilofrin Pilocarpine nitrate for system suitability CRS Pilocarpine nitrate CRS Pilocarpine nitrate USP/EP/BP Pilocarpine NitrateQ: What is Pilocarpine Nitrate Q: What is the CAS Number of Pilocarpine Nitrate Q: What is the storage condition of Pilocarpine Nitrate Q: What are the applications of Pilocarpine Nitrate Pilocarpine Nitrate (1539009) Pilocarpinenitratesal Pilocarpine,Inhibitor,inhibit,mAChR,Muscarinic acetylcholine receptor,Pilocarpine nitrate (2R,3R)-2-ethyl-3-(hydroxymethyl)-4-(1-methyl-1H-imidazol-5-yl)butanoic acid (isopilocarpic acid) Ametryn Impurity 21(Simetryne) Pilocarpine nitrate, 10 mM in DMSO Pilocarpine Nitrate Impurity Ⅰ:(3R,4R)-3-ethyl-4-((1-Methyl-1H-iMidazol-5-yl)Methyl)dihydrofuran-2(3H)-one nitrate 148-72-1 C11H16N2O2HNO3 Alkaloids (Others) Alkaloids Inhibitors AgonistsDrugs of Abuse Chemical Structure Cholinergics Neurotransmitters Others Alkaloids Alkaloids (Others) Biochemistry API