Pilocarpine nitrate
- CAS No.
- 148-72-1
- Chemical Name:
- Pilocarpine nitrate
- Synonyms
- Nitrat;Pilocarpine nitrate for system suitability CRS;Pilagan;pilofrin;Pilocarpinnitrat;Einecs 205-723-7;Pilocarpin Nitrate;Pilocarpini nitras;PILOCARPINE NITRATE;p.v.carpineliquifilm
- CBNumber:
- CB4237796
- Molecular Formula:
- C11H17N3O5
- Molecular Weight:
- 271.27
- MDL Number:
- MFCD00078497
- MOL File:
- 148-72-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Pilocarpine nitrate for system suitability European Pharmacopoeia (EP) Reference Standard | Y0000106 | 20 mg | $167 |
| Pilocarpine nitrate European Pharmacopoeia (EP) Reference Standard | P1700000 | 50 mg | $127 |
| Pilocarpine nitrate meets USP testing specifications | P0597 | 5g | $500 |
| Pilocarpine nitrate meets USP testing specifications | P0597 | 25g | $1730 |
| Pilocarpine nitrate British Pharmacopoeia (BP) Reference Standard | BP503 | 200MG | $223 |
| More product size | |||
| Melting point | 173,5-174°C |
|---|---|
| alpha | D +77 to +83° (c = 10) |
| refractive index | 81 ° (C=2, H2O) |
| storage temp. | 2-8°C |
| solubility | H2O: 0.1 g/mL, clear, very faintly yellow |
| form | powder |
| color | white |
| optical activity | [α]25/D +83°, c = 10 in H2O(lit.) |
| Water Solubility | H2O: 100mg/mL |
| Merck | 14,7424 |
| BRN | 4171406 |
| Major Application | pharmaceutical (small molecule) |
| InChI | 1S/C11H16N2O2.HNO3/c1-3-10-8(6-15-11(10)14)4-9-5-12-7-13(9)2;2-1(3)4/h5,7-8,10H,3-4,6H2,1-2H3;(H,2,3,4)/t8-,10-;/m0./s1 |
| InChIKey | PRZXEPJJHQYOGF-GNAZCLTHSA-N |
| SMILES | O[N+]([O-])=O.CC[C@H]1[C@H](COC1=O)Cc2cncn2C |
| CAS DataBase Reference | 148-72-1(CAS DataBase Reference) |
| FDA UNII | M20T465H6J |
| EPA Substance Registry System | Pilocarpine nitrate (148-72-1) |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() ![]() GHS03,GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H272-H302-H330 |
| Precautionary statements | P210-P220-P260-P264-P301+P312-P304+P340+P310 |
| PPE | Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges |
| Hazard Codes | Xn,T+ |
| Risk Statements | 22-26/28 |
| Safety Statements | 1-25-45 |
| RIDADR | 3087 |
| WGK Germany | 3 |
| RTECS | TK1455000 |
| F | 3-10 |
| TSCA | TSCA listed |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| HS Code | 2939800000 |
| Storage Class | 5.1B - Oxidizing hazardous materials |
| Hazard Classifications | Acute Tox. 2 Inhalation Acute Tox. 4 Oral Ox. Sol. 2 |
| Toxicity | LD50 oral in rat: 911mg/kg |
Pilocarpine nitrate price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | Y0000106 | Pilocarpine nitrate for system suitability European Pharmacopoeia (EP) Reference Standard | 148-72-1 | 20 mg | $167 | 2026-03-19 | Buy |
| Sigma-Aldrich | P1700000 | Pilocarpine nitrate European Pharmacopoeia (EP) Reference Standard | 148-72-1 | 50 mg | $127 | 2026-03-19 | Buy |
| Sigma-Aldrich | P0597 | Pilocarpine nitrate meets USP testing specifications | 148-72-1 | 5g | $500 | 2026-03-19 | Buy |
| Sigma-Aldrich | P0597 | Pilocarpine nitrate meets USP testing specifications | 148-72-1 | 25g | $1730 | 2026-03-19 | Buy |
| Sigma-Aldrich | BP503 | Pilocarpine nitrate British Pharmacopoeia (BP) Reference Standard | 148-72-1 | 200MG | $223 | 2026-03-19 | Buy |
Pilocarpine nitrate Chemical Properties,Uses,Production
Chemical Properties
White or almost white, crystalline powder or colourless crystals, sensitive to light.
Uses
antiglaucoma agent, miotic
Uses
Antiglaucoma drug;Cholinergic
Uses
Pilocarpine nitrate salt has been used to measure bronchoconstriction and M2 and M3 muscarinic receptor function in vivo. It has also been used to induce electrographic and behavioral seizures and to study the different patterns of neuronal activation and neurodegeneration in Proechimys rats and Wistar rats.
brand name
Pilagan (Allergan).
General Description
Pilocarpine mononitrate occursas shining white crystals that are not hygroscopic butare light sensitive. It is soluble in water (1:4) and alcohol(1:75) but insoluble in chloroform and ether. Aqueoussolutions are slightly acid to litmus and may be sterilizedin the autoclave. The alkaloid is incompatible with alkalies,iodides, silver nitrate, and reagents that precipitatealkaloids.
Biochem/physiol Actions
Pilocarpine is a cholinergic muscarinic agonist, useful in inducing epilepsy in animal models. It is specially used to study the pathogenesis of epileptogenesis and pharmacoresistant epilepsy. Pilocarpine application is more popular among the rat and mice models.
Pilocarpine nitrate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20124 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21591 | 55 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32467 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 18895 | 58 |
| AFINE CHEMICALS LIMITED | +86-0571-85134551 | sales@afinechem.com | China | 15080 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52705 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39040 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +86-571-86217390; +8618058761490 | info@gihichemicals.com | China | 49968 | 58 |
View Lastest Price from Pilocarpine nitrate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-04-22 | Pilocarpine nitrate
148-72-1
|
US $92.00 / mg | 98.00% | 10g | TargetMol Chemicals Inc. | ||
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2026-04-22 | Pilocarpine nitrate
148-72-1
|
US $92.00 / mg | 98.00% | 10g | TargetMol Chemicals Inc. | ||
![]() |
2025-11-18 | Pilocarpine nitrate USP/EP/BP
148-72-1
|
US $1.10 / g | 1g | 99.9% | 100 Tons min | Dideu Industries Group Limited |
-

- Pilocarpine nitrate
148-72-1
- US $92.00 / mg
- 98.00%
- TargetMol Chemicals Inc.
-

- Pilocarpine nitrate
148-72-1
- US $92.00 / mg
- 98.00%
- TargetMol Chemicals Inc.
-

- Pilocarpine nitrate USP/EP/BP
148-72-1
- US $1.10 / g
- 99.9%
- Dideu Industries Group Limited






