2,6-Dichloronicotinonitrile
- CAS No.
- 40381-90-6
- Chemical Name:
- 2,6-Dichloronicotinonitrile
- Synonyms
- 2,6-Dichloronicotino;oropyridine-3-carbonitriL;2,6-DICHLORONICOTINONITRILE;2,6-Dichloro-3-Cyanopyridine;2,6-dichloro-3-cyannopyridine;2,6- twochloro -3-cyanopyridine;2,6-Dichloronicotinonitrile 97%;2,6-Dichloro-3-cyanopyridine >2,6-Dichloro-pyridin-3-carbonitrile;2,6-Dichloropyridine-3-acetonitrile
- CBNumber:
- CB4240189
- Molecular Formula:
- C6H2Cl2N2
- Molecular Weight:
- 173
- MDL Number:
- MFCD03411341
- MOL File:
- 40381-90-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 2,6-Dichloropyridine-3-carbonitrile 97% | 703079 | 1g | $76 |
| 2,6-Dichloropyridine-3-carbonitrile 97% | 684872 | 1g | $95.5 |
| 2,6-Dichloro-3-cyanopyridine >98.0%(GC) | D4650 | 200mg | $22 |
| 2,6-Dichloro-3-cyanopyridine >98.0%(GC) | D4650 | 1g | $62 |
| 2,6-Dichloro-3-cyanopyridine ≥98%(GC) | 44761 | 250MG | $36.96 |
| More product size | |||
| Melting point | 121-124 °C |
|---|---|
| Boiling point | 286.0±35.0 °C(Predicted) |
| Density | 1.49±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| pka | -5.33±0.10(Predicted) |
| form | powder to crystal |
| color | White to Light yellow |
| Sensitive | Moisture Sensitive |
| InChI | InChI=1S/C6H2Cl2N2/c7-5-2-1-4(3-9)6(8)10-5/h1-2H |
| InChIKey | LFCADBSUDWERJT-UHFFFAOYSA-N |
| SMILES | C1(Cl)=NC(Cl)=CC=C1C#N |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H315-H318-H335 | |||||||||
| Precautionary statements | P280-P301+P310+P330-P302+P352-P305+P351+P338+P310 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges | |||||||||
| Hazard Codes | T | |||||||||
| Risk Statements | 25-41-37/38 | |||||||||
| Safety Statements | 26-39-45 | |||||||||
| RIDADR | UN 2811 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | Ⅲ | |||||||||
| HS Code | 29333990 | |||||||||
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
|||||||||
| Hazard Classifications | Acute Tox. 3 Oral Eye Dam. 1 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
2,6-Dichloronicotinonitrile price More Price(46)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 703079 | 2,6-Dichloropyridine-3-carbonitrile 97% | 40381-90-6 | 1g | $76 | 2023-06-20 | Buy |
| Sigma-Aldrich | 684872 | 2,6-Dichloropyridine-3-carbonitrile 97% | 40381-90-6 | 1g | $95.5 | 2022-05-15 | Buy |
| TCI Chemical | D4650 | 2,6-Dichloro-3-cyanopyridine >98.0%(GC) | 40381-90-6 | 200mg | $22 | 2026-04-30 | Buy |
| TCI Chemical | D4650 | 2,6-Dichloro-3-cyanopyridine >98.0%(GC) | 40381-90-6 | 1g | $62 | 2026-04-30 | Buy |
| Chem-Impex | 44761 | 2,6-Dichloro-3-cyanopyridine ≥98%(GC) | 40381-90-6 | 250MG | $36.96 | 2026-05-19 | Buy |
2,6-Dichloronicotinonitrile Chemical Properties,Uses,Production
Chemical Properties
Brown yellow powder
Uses
2,6-Dichloro-3-cyanopyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Synthesis Reference(s)
The Journal of Organic Chemistry, 44, p. 2693, 1979 DOI: 10.1021/jo01329a020
Synthesis
76175-82-1
40381-90-6
General procedure for the synthesis of 2,6-dichloronicotinonitrile from N-(2,6-dichloropyridin-3-yl)acetamide: To a solution of dichloromethane (100 mL) containing 2,6-dichloro-3-acetamidopyridine (6.3 g, 55% purity) and pyridine (4.93 mL, 61 mmol) was slowly added trifluoroacetic anhydride (4.23 mL, 30 mmol). The reaction mixture was stirred overnight at room temperature and subsequently concentrated under reduced pressure. The crude product was purified by fast chromatography using 85% hexane and 15% ethyl acetate as eluents to give a light yellow product (1.77 g, 90% yield).HPLC analysis showed a retention time of 10.26 min (90% purity) and mass spectrometry analysis showed the molecular ion peak [M+H]+ = 172.9, and the theoretical molecular weight for the molecular formula C6H2Cl2N2 was 171.9 g/mol.
References
[1] Patent: US2002/156087, 2002, A1
2,6-Dichloronicotinonitrile Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10404 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Shenzhen Excellent Biotech Co., Ltd. | 13480692018 | ramyan@ex-biotech.com | CHINA | 954 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49955 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29794 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9636 | 58 |
View Lastest Price from 2,6-Dichloronicotinonitrile manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-11-18 | 2,6-Dichloronicotinonitrile
40381-90-6
|
US $1.10 / g | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited |
-
- 2,6-Dichloronicotinonitrile
40381-90-6
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
