ACETIC ACID, 2-CYCLOBUTYLIDENE-, ETHYL ESTER
- CAS No.
- 27741-65-7
- Chemical Name:
- ACETIC ACID, 2-CYCLOBUTYLIDENE-, ETHYL ESTER
- Synonyms
- Ethyl cyclobutylideneacetate;Ethyl2-cyclobutylideneacetate;Carbethoxymethylenecyclobutane;Ethyl cyclobutylideneacetate 97%;Cyclobutylidene-acetic acid ethyl ester;2-Cyclobutylideneacetic acid ethyl ester;ethyl 2-cyclobutylideneacetate - [E47017];Acetic acid, cyclobutylidene-, ethyl ester;ACETIC ACID, 2-CYCLOBUTYLIDENE-, ETHYL ESTER
- CBNumber:
- CB42468538
- Molecular Formula:
- C8H12O2
- Molecular Weight:
- 140.18
- MDL Number:
- MFCD11977311
- MOL File:
- 27741-65-7.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Ethyl2-cyclobutylideneacetate | 2660AB | 250mg | $131 |
| Ethyl cyclobutylideneacetate | 2323-1-43 | 250mg | $152 |
| Ethyl cyclobutylideneacetate | 2323-1-43 | 1g | $240 |
| Ethyl cyclobutylideneacetate | 2323-1-43 | 5G | $672 |
| Ethyl cyclobutylideneacetate 97% | 083613 | 1g | $414 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P280-P305+P351+P338 |
| HS Code | 2916199590 |
ACETIC ACID, 2-CYCLOBUTYLIDENE-, ETHYL ESTER price More Price(23)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| AK Scientific | 2660AB | Ethyl2-cyclobutylideneacetate | 27741-65-7 | 250mg | $131 | 2021-12-16 | Buy |
| SynQuest Laboratories | 2323-1-43 | Ethyl cyclobutylideneacetate | 27741-65-7 | 250mg | $152 | 2021-12-16 | Buy |
| SynQuest Laboratories | 2323-1-43 | Ethyl cyclobutylideneacetate | 27741-65-7 | 1g | $240 | 2021-12-16 | Buy |
| SynQuest Laboratories | 2323-1-43 | Ethyl cyclobutylideneacetate | 27741-65-7 | 5G | $672 | 2021-12-16 | Buy |
| Matrix Scientific | 083613 | Ethyl cyclobutylideneacetate 97% | 27741-65-7 | 1g | $414 | 2021-12-16 | Buy |
ACETIC ACID, 2-CYCLOBUTYLIDENE-, ETHYL ESTER Chemical Properties,Uses,Production
Synthesis
867-13-0
1191-95-3
27741-65-7
A 25 mL THF solution of triethyl phosphonoacetate (44.8 g) was added dropwise to a suspension of THF (150 mL) containing NaH (8.0 g, 60% oil dispersion) over 40 min at 0-10 °C. The reaction mixture was kept at 0-10°C with continued stirring for 0.5 hr. Subsequently, a 25 mL THF solution of cyclobutanone (14.0 g) was added dropwise at the same temperature. The reaction mixture was stirred at 0-10 °C for 2 hours. Next, 50 mL of water was slowly added at 20-30 °C. After removing the organic solvent by distillation under reduced pressure, 150 mL of water was added. The aqueous solution was extracted using MTBE (3 x 100mL). The organic phases were combined and washed with 100 mL of water and subsequently dried with anhydrous MgSO4. After filtration, the solvent was evaporated to give the crude product, which was purified by fractional distillation (81-82 °C/19 mbar) to give 22.2 g (79% yield) of ethyl 2-cyclobutylideneacetate as a colorless liquid. The product was characterized by the following data: 1HNMR (500 MHz, CDCl3) δ 5.58 (m, 1H), 4.13 (q, 2H, J = 7.1 Hz), 3.15-3.12 (m, 2H), 2.85-2.82 (m, 2H), 2.12-2.06 (m, 2H), 1.26 (t, 3H, J = 7.1 Hz); 13C NMR (125 MHz, CDCl3) δ 167.60,166.60,112.38,59.53,33.75,32.32,17.66,14.36; MS (m/z) 140.1; ESI-HRMS m/z calculated for C8H12O2 [M+H]+ 141.0910, found 141.0911.
References
[1] Journal of Organic Chemistry, 2016, vol. 81, # 3, p. 1057 - 1074
[2] Journal of the Chemical Society. Perkin Transactions 2, 1999, # 5, p. 937 - 945
[3] Tetrahedron Letters, 2015, vol. 56, # 45, p. 6287 - 6289
[4] Patent: WO2016/37534, 2016, A1. Location in patent: Page/Page column 19
[5] Patent: US2017/27172, 2017, A1. Location in patent: Paragraph 0203
ACETIC ACID, 2-CYCLOBUTYLIDENE-, ETHYL ESTER Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29799 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19987 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8615965530500 | nickzhang@hangyubiotech.com | China | 10996 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 43339 | 58 |
| Wuhan Chiral Man Biotechnology Co., Ltd | +86-027-81610301 +86-18986082610 | luanfengping@flyblueprint.com | China | 196 | 58 |
View Lastest Price from ACETIC ACID, 2-CYCLOBUTYLIDENE-, ETHYL ESTER manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2020-01-13 | ACETIC ACID, 2-CYCLOBUTYLIDENE-, ETHYL ESTER
27741-65-7
|
US $5.00 / KG | 1KG | 98% | 100KG | Career Henan Chemical Co |
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- ACETIC ACID, 2-CYCLOBUTYLIDENE-, ETHYL ESTER
27741-65-7
- US $5.00 / KG
- 98%
- Career Henan Chemical Co
