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ChemicalBook >> CAS DataBase List >>5,6-Dihydro-4H-pyrrolo[1,2-b]pyrazole

5,6-Dihydro-4H-pyrrolo[1,2-b]pyrazole

5,6-Dihydro-4H-pyrrolo[1,2-b]pyrazole Structure
5,6-Dihydro-4H-pyrrolo[1,2-b]pyrazole structure
CAS No.
107862-65-7
Chemical Name:
5,6-Dihydro-4H-pyrrolo[1,2-b]pyrazole
Synonyms
4H,5H,6H-pyrrolo[1,2-b]pyrazole;5,6-Dihydro-4H-pyrrolo[1,2-b]pyrazole;4H-Pyrrolo[1,2-b]pyrazole, 5,6-dihydro-
CBNumber:
CB42499064
Molecular Formula:
C6H8N2
Molecular Weight:
108.14
MDL Number:
MFCD18072560
MOL File:
107862-65-7.mol
Last updated:2026-05-28 02:04:58
Request For Quotation

5,6-Dihydro-4H-pyrrolo[1,2-b]pyrazole Properties

Boiling point 206℃
Density 1.23
Flash point 78℃
pka 2.85±0.20(Predicted)
InChI InChI=1S/C6H8N2/c1-2-6-3-4-7-8(6)5-1/h3-4H,1-2,5H2
InChIKey LQKUERRPRLVSLZ-UHFFFAOYSA-N
SMILES N1=CC=C2CCCN12

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2933199090

5,6-Dihydro-4H-pyrrolo[1,2-b]pyrazole price More Price(37)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 162004 5,6-Dihydro-4H-pyrrolo[1,2-b]pyrazole Asreported 107862-65-7 50mg $531 2026-06-03 Buy
Synthonix D16430 5,6-Dihydro-4H-pyrrolo[1,2-b]pyrazole 97% 107862-65-7 100mg $200 2026-05-06 Buy
Synthonix D16430 5,6-Dihydro-4H-pyrrolo[1,2-b]pyrazole 97% 107862-65-7 250mg $330 2026-05-06 Buy
Synthonix D16430 5,6-Dihydro-4H-pyrrolo[1,2-b]pyrazole 97% 107862-65-7 500mg $560 2026-05-06 Buy
Synthonix D16430 5,6-Dihydro-4H-pyrrolo[1,2-b]pyrazole 97% 107862-65-7 1g $870 2026-05-06 Buy
Product number Packaging Price Buy
162004 50mg $531 Buy
D16430 100mg $200 Buy
D16430 250mg $330 Buy
D16430 500mg $560 Buy
D16430 1g $870 Buy

5,6-Dihydro-4H-pyrrolo[1,2-b]pyrazole Chemical Properties, Uses, Production

Uses

5,6-Dihydro-4H-pyrrolo[1,2-b]pyrazole is used in the preparation of withasomnine molecules, pyrazole alkaloids, for their application towards antiinflammatory compounds and analgesics.

Synthesis

3-(3-chloropropyl)-1H-pyrazole

174790-34-2

5,6-Dihydro-4H-pyrrolo[1,2-b]pyrazole

107862-65-7

3-(3-Chloropropyl)-1H-pyrazole (500 mg, 3.5 mmol) was used as a starting material and dissolved in a mixed solvent of isopropanol/water (5 mL/1 mL) and potassium hydroxide (389 mg, 6.9 mmol) was added. The reaction mixture was stirred at 90 °C for 2 hours. After completion of the reaction, the mixture was cooled to room temperature and extracted with dichloromethane (3 x 20 mL). The organic layers were combined, dried with anhydrous magnesium sulfate, filtered and concentrated under reduced pressure. Purification of the residue by silica gel column chromatography (petroleum ether: ethyl acetate = 6:1 to 2:1) afforded 5,6-dihydro-4H-pyrrolo[1,2-B]pyrazole (150 mg, 39.6% yield) as a brown oil.LC-MS (ESI) detection: 109 [M + 1].

References

[1] Patent: WO2017/35353, 2017, A1. Location in patent: Paragraph 0953
[2] Tetrahedron Letters, 1996, vol. 37, # 7, p. 1095 - 1096
[3] Patent: WO2013/52394, 2013, A1. Location in patent: Paragraph 00248
[4] Tetrahedron, 2013, vol. 69, # 34, p. 7139 - 7146
[5] Patent: WO2013/192125, 2013, A1. Location in patent: Page/Page column 135

5,6-Dihydro-4H-pyrrolo[1,2-b]pyrazole Preparation Products And Raw materials

Raw materials

3-(3-chloropropyl)-1H-pyrazole Potassium hydroxide Isopropyl alcohol

Preparation Products

5,6-Dihydro-4H-pyrrolo[1,2-b]pyrazole Suppliers

Global Suppliers ( 51)
Supplier Tel Email Country ProdList Advantage
Shanghai TuZhi Chemical Co., Ltd. 19542790274 2119559397@qq.com China 751 50
Shanghai Boyle Chemical Co., Ltd. sales@boylechem.com China 2915 55
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Atop-Pharma (Shanghai) Technology Co., Ltd. +86 (21) 5196-9732 China 996 57
CEG Chemical Science&Technology Co., Ltd. Mobile:13665161512 China 1784 58
Shanghai Hong-chuang Pharma Tech Co., Ltd. 18151128828 hc-sales@foxmail.com China 2635 55
Tongling HengYou Biotechnology Co., Ltd. 021-50426030 13856289449;13124863828 2630597085@qq.com China 1885 55
Changzhou Hopschain Chemical Co.,Ltd. 85528066 13775048983 sales@hopschem.com China 31548 55
parabiochem 025-83453382-8005 sale@parabiochem.com China 9577 55
Supplier Advantage
Shanghai TuZhi Chemical Co., Ltd. 50
Shanghai Boyle Chemical Co., Ltd. 55
J & K SCIENTIFIC LTD. 76
Shanghai Hanhong Scientific Co.,Ltd. 64
Atop-Pharma (Shanghai) Technology Co., Ltd. 57
CEG Chemical Science&Technology Co., Ltd. 58
Shanghai Hong-chuang Pharma Tech Co., Ltd. 55
Tongling HengYou Biotechnology Co., Ltd. 55
Changzhou Hopschain Chemical Co.,Ltd. 55
parabiochem 55

View Latest Price from 5,6-Dihydro-4H-pyrrolo[1,2-b]pyrazole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5,6-Dihydro-4H-pyrrolo[1,2-b]pyrazole pictures 2020-01-13 5,6-Dihydro-4H-pyrrolo[1,2-b]pyrazole
107862-65-7
 $9.80 1g ≥99% 100kg Career Henan Chemical Co

5,6-Dihydro-4H-pyrrolo[1,2-b]pyrazole Spectrum

5,6-Dihydro-4H-pyrrolo[1,2-b]pyrazole(107862-65-7)1HNMR

107862-65-7 (5,6-Dihydro-4H-pyrrolo[1,2-b]pyrazole) Related Search:

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5,6-Dihydro-4H-pyrrolo[1,2-b]pyrazole 4H-Pyrrolo[1,2-b]pyrazole, 5,6-dihydro- 4H,5H,6H-pyrrolo[1,2-b]pyrazole 107862-65-7