(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol
- CAS No.
- 106083-71-0
- Chemical Name:
- (+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol
- Synonyms
- GW 353162;GW-353162A;BW-306U;Bupropion Morpholinol IMpurity;SS-hydroxybupropion hydrochloride;Bupropion Morpholinol (2S,3S)-Isomer;(2S,3S)-Hydroxybupropion hydrochloride;Bupropion Morpholinol IMpurity (HCl Salt);(2S,3S)-Hydroxybupropion hydrochloride >=98% (HPLC);(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol;(2S,3S)-2-(3-Chlorophenyl)-3,5,5-trimethyl-2-morpholinol hydrochloride
- CBNumber:
- CB42502638
- Molecular Formula:
- C13H19Cl2NO2
- Molecular Weight:
- 292.2
- MDL Number:
- MFCD10565921
- MOL File:
- 106083-71-0.mol
- MSDS File:
- SDS
Product description | Number | Pack Size | Price |
(2S,3S)-Hydroxybupropion hydrochloride ≥98% (HPLC) | H3167 | 5mg | $146.3 |
(2S,3S)-Hydroxybupropion hydrochloride ≥98% (HPLC) | H3167 | 25mg | $609 |
GW-353162A 95.00% | API0004715 | 25MG | $1029.63 |
Radafaxine(hydrochloride) 99.88% | CS-3815 | 10mg | $192 |
Radafaxine(hydrochloride) 99.88% | CS-3815 | 5mg | $102 |
More product size |
storage temp. | -20°C |
---|---|
solubility | DMSO: ≥12mg/mL |
form | powder |
color | white to tan |
FDA UNII | SYD411HZ3S |
UNSPSC Code | 12352200 |
NACRES | NA.77 |
(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol price More Price(9)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | H3167 | (2S,3S)-Hydroxybupropion hydrochloride ≥98% (HPLC) | 106083-71-0 | 5mg | $146.3 | 2025-07-31 | Buy |
Sigma-Aldrich | H3167 | (2S,3S)-Hydroxybupropion hydrochloride ≥98% (HPLC) | 106083-71-0 | 25mg | $609 | 2025-07-31 | Buy |
American Custom Chemicals Corporation | API0004715 | GW-353162A 95.00% | 106083-71-0 | 25MG | $1029.63 | 2021-12-16 | Buy |
ChemScene | CS-3815 | Radafaxine(hydrochloride) 99.88% | 106083-71-0 | 10mg | $192 | 2021-12-16 | Buy |
ChemScene | CS-3815 | Radafaxine(hydrochloride) 99.88% | 106083-71-0 | 5mg | $102 | 2021-12-16 | Buy |
(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol Chemical Properties,Uses,Production
Uses
Antidepressant; antianxiety.
General Description
(2S,3S)-hydroxybupropion is a major metabolite of bupropion.
Biochem/physiol Actions
(2S,3S)-hydroxybupropion is a dopamine transporter (DAT) and norepinephrine transporter (NET) transporters inhibitor and nicotinic acetylcholine receptor (nAChR) family modulator. Hydroxybupropions were reported to contribute to antidepressant and perhaps smoking cessation activities. Both (2S,3S) and (2R,3R) metabolites reverse affective and somatic withdrawal signs in nicotine-dependent mice, but (2S,3S)-hydroxybupropion is more potent. (2S,3S)-hydroxybupropion significantly decreases the development of nicotine reward in mice.
(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14332 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32434 | 58 |
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
China National Standard Pharmaceutical Corporation Limited | +8615391658522 | overseasales@yongstandards.com | China | 11922 | 58 |
Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
Syntechem Co.,Ltd | info@syntechem.com | China | 12984 | 57 | |
Haoyuan Chemexpress Co., Ltd. | 021-58950125 | info@chemexpress.com | China | 7552 | 61 |
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