ChemicalBook >> CAS DataBase List >>3-Bromo-5-fluoro-4-pyridinecarboxylic acid

3-Bromo-5-fluoro-4-pyridinecarboxylic acid

CAS No.
955372-86-8
Chemical Name:
3-Bromo-5-fluoro-4-pyridinecarboxylic acid
Synonyms
3-BroMo-5-fluoroisonicotinic acid;3-Bromo-5-fluoro-4-pyridinecarboxylic acid;4-Pyridinecarboxylic acid, 3-broMo-5-fluoro-
CBNumber:
CB42503963
Molecular Formula:
C6H3BrFNO2
Molecular Weight:
220
MDL Number:
MFCD13181633
MOL File:
955372-86-8.mol
MSDS File:
SDS
Last updated:2026-05-28 02:09:38
Product description Number Pack Size Price
3-Bromo-5-fluoro-pyridine-4-carboxylic acid 96% PC520692 100mg $21
3-Bromo-5-fluoro-pyridine-4-carboxylic acid 96% PC520692 250mg $24
3-Bromo-5-fluoro-pyridine-4-carboxylic acid 96% PC520692 1g $29
3-Bromo-5-fluoro-pyridine-4-carboxylic acid 96% PC520692 5g $139
3-Bromo-5-fluoro-pyridine-4-carboxylic acid 96% PC520692 25g $621

3-Bromo-5-fluoro-4-pyridinecarboxylic acid Properties

Boiling point 367.4±42.0 °C(Predicted)
Density 1.903±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka 1.09±0.10(Predicted)
Appearance Light yellow to brown Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P280-P301+P312-P305+P351+P338
HS Code  2933399990

3-Bromo-5-fluoro-4-pyridinecarboxylic acid price More Price(77)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific PC520692 3-Bromo-5-fluoro-pyridine-4-carboxylic acid 96% 955372-86-8 100mg $21 2026-06-04 Buy
Apolloscientific PC520692 3-Bromo-5-fluoro-pyridine-4-carboxylic acid 96% 955372-86-8 250mg $24 2026-06-04 Buy
Apolloscientific PC520692 3-Bromo-5-fluoro-pyridine-4-carboxylic acid 96% 955372-86-8 1g $29 2026-06-04 Buy
Apolloscientific PC520692 3-Bromo-5-fluoro-pyridine-4-carboxylic acid 96% 955372-86-8 5g $139 2026-06-04 Buy
Apolloscientific PC520692 3-Bromo-5-fluoro-pyridine-4-carboxylic acid 96% 955372-86-8 25g $621 2026-06-04 Buy
Product number Packaging Price Buy
PC520692 100mg $21 Buy
PC520692 250mg $24 Buy
PC520692 1g $29 Buy
PC520692 5g $139 Buy
PC520692 25g $621 Buy

3-Bromo-5-fluoro-4-pyridinecarboxylic acid Chemical Properties,Uses,Production

Synthesis

Carbon dioxide

124-38-9

3-Bromo-5-fluoro-4-pyridinecarboxylic acid

955372-86-8

General procedure for the synthesis of 3-bromo-5-fluoroisonicotinic acid from carbon dioxide: Intermediate 6: 3-bromo-5-fluoroisonicotinic acid; n-butyllithium (12.5 mL, 2.5 M solution of THF, 31.3 mmol) was slowly added to a solution of diisopropylamine (4.4 mL, 31.3 mmol) in THF (200 mL) at 0 °C and stirred for 15 min, then cooled to -78 °C. 3-Bromo-5-fluoropyridine (5.0 g, 28.4 mmol) solid was added and the resulting solution was stirred at -78 °C for 10 min. A gaseous carbon dioxide bulb was passed through a cannula into the solution for 30 min and the resulting solution was stirred for 2 h. The solution was warmed from -78 °C to room temperature. The reaction solution was concentrated by rotary evaporation, diluted with 2 M NaOH and washed with EtOAc. The aqueous solution was acidified with 1M HCl and extracted with EtOAc. The organic extract was washed with brine, dried over MgSO4, filtered and concentrated to give the target product 3-bromo-5-fluoroisonicotinic acid (4.75 g, 76% yield) as a solid.

References

[1] Patent: WO2007/123936, 2007, A1. Location in patent: Page/Page column 32; 67-68

3-Bromo-5-fluoro-4-pyridinecarboxylic acid Preparation Products And Raw materials

3-Bromo-5-fluoro-4-pyridinecarboxylic acid Suppliers

Global( 90)Suppliers
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Alchem Pharmtech,Inc.
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career henan chemical co
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Zhejiang J&C Biological Technology Co.,Limited
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Henan Alfa Chemical Co., Ltd
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Hangzhou MolCore BioPharmatech Co.,Ltd.
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Aceschem Inc.
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Aladdin Scientific
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Suzhou ARTK Medchem Co., Ltd.
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Cochemical Co. Ltd.
+86-029-86115547 +86-17791676824 sales@cochemical.com China 3952 58
Shanghai Likang New Materials Co., Limited
+86-16631818819 +86-17736933208 3684455296@qq.com China 9300 58

View Lastest Price from 3-Bromo-5-fluoro-4-pyridinecarboxylic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-Bromo-5-fluoro-4-pyridinecarboxylic acid pictures 2019-12-20 3-Bromo-5-fluoro-4-pyridinecarboxylic acid
955372-86-8
$1.00 1KG 99% Career Henan Chemical Co

3-Bromo-5-fluoro-4-pyridinecarboxylic acid Spectrum

3-Bromo-5-fluoro-4-pyridinecarboxylic acid 3-BroMo-5-fluoroisonicotinic acid 4-Pyridinecarboxylic acid, 3-broMo-5-fluoro- 955372-86-8