ChemicalBook >> CAS DataBase List >>N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid 1,5-dimethyl ester

N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid 1,5-dimethyl ester

N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid 1,5-dimethyl ester structure

CAS No.: 155405-81-5

Chemical Name:: N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid 1,5-dimethyl ester

Synonyms: Pemetrexed methyl ester;PeMetrexed DiMethyl Ester;Pemetrexed Impurity 21(Pemetrexed Dimethyl Ester);(E)-4-(4-((2-amino-6-oxo-1,6-dihydropyrimidin-4-yl)imino)butyl)benzoic acid;4-[2-(2-Amino-4-oxo-4,7-Dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-yl)ethyl]benzoic acid diethyl ester sulfonate;imethyl(2R)-2-[[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioate;dimethyl (2R)-2-[[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioate;N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid dimethyl ester;1,5-dimethyl (2S)-2-{[4-(2-{2-amino-4-oxo-1H,7H-pyrrolo[2,3-d]pyrimidin-5-yl}ethyl)phenyl]formamido}pentanedioate;N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid 1,5-dimethyl ester

CBNumber:: CB42510112

Molecular Formula:: C22H25N5O6

Molecular Weight:: 455.46

MDL Number:

MOL File:: 155405-81-5.mol

Last updated:2026-05-28 02:12:27

Product description	Number	Pack Size	Price
Pemetrexed Methyl Ester	019177	2.5mg	$446
Pemetrexed methyl ester	FP26785	5g	$1687.4
Pemetrexed methyl ester	FP26785	10g	$2336.4
1,5-Dimethyl (2S)-2-{[4-(2-{2-Amino-4-Oxo-1H,7H-Pyrrolo[2,3-D]Pyrimidin-5-Yl}Ethyl)Phenyl]Formamido}Pentanedioate 95%	AA00AE1A	100mg	$113
1,5-Dimethyl (2S)-2-{[4-(2-{2-Amino-4-Oxo-1H,7H-Pyrrolo[2,3-D]Pyrimidin-5-Yl}Ethyl)Phenyl]Formamido}Pentanedioate 95%	AA00AE1A	250mg	$213
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N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid 1,5-dimethyl ester Properties

Melting point	>85°C (Subl.)
Density	1.43±0.1 g/cm3(Predicted)
storage temp.	Refrigerator
solubility	Dimethylformamide, DMSO, Methanol
pka	13.01±0.46(Predicted)
form	Solid
color	Green
Major Application	pharmaceutical small molecule
UNSPSC Code	12352200
NACRES	NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS08,GHS07
Signal word	Danger
Hazard statements	H315-H341-H360FD-H372
Precautionary statements	P202-P260-P264-P280-P302+P352-P308+P313
target organs	Blood,Immune system,Testes
WGK Germany	WGK 3
Storage Class	6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects
Hazard Classifications	Muta. 2 Repr. 1A Skin Irrit. 2 STOT RE 1

N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid 1,5-dimethyl ester price More Price(10)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Usbiological	019177	Pemetrexed Methyl Ester	155405-81-5	2.5mg	$446	2026-06-03	Buy
Biosynth	FP26785	Pemetrexed methyl ester	155405-81-5	5g	$1687.4	2026-06-04	Buy
Biosynth	FP26785	Pemetrexed methyl ester	155405-81-5	10g	$2336.4	2026-06-04	Buy
aablocks	AA00AE1A	1,5-Dimethyl (2S)-2-{[4-(2-{2-Amino-4-Oxo-1H,7H-Pyrrolo[2,3-D]Pyrimidin-5-Yl}Ethyl)Phenyl]Formamido}Pentanedioate 95%	155405-81-5	100mg	$113	2026-05-28	Buy
aablocks	AA00AE1A	1,5-Dimethyl (2S)-2-{[4-(2-{2-Amino-4-Oxo-1H,7H-Pyrrolo[2,3-D]Pyrimidin-5-Yl}Ethyl)Phenyl]Formamido}Pentanedioate 95%	155405-81-5	250mg	$213	2026-05-28	Buy

Product number	Packaging	Price	Buy
019177	2.5mg	$446	Buy
FP26785	5g	$1687.4	Buy
FP26785	10g	$2336.4	Buy
AA00AE1A	100mg	$113	Buy
AA00AE1A	250mg	$213	Buy

N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid 1,5-dimethyl ester Chemical Properties,Uses,Production

Chemical Properties

Brown Solid

Uses

Protected Pemetrexed.

N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid 1,5-dimethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid 1,5-dimethyl ester Suppliers

Global( 59)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1803	55
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14332	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58
SIMAGCHEM CORP	+86-5922680277 +86-13806087780	sale@simagchem.com	China	17346	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30224	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	28675	58
Suzhou ARTK Medchem Co., Ltd.	+8618118463618	sales1@artkmedchem.com	China	39021	58
DAYANG CHEM (HANGZHOU) CO.,LTD	+86-88938639 +86-17705817739	info@dycnchem.com	China	53803	58
Mainchem Co., Ltd.	--	sarah@mainchem.com	China	6545	58
J & K SCIENTIFIC LTD.	18210857532; 18210857532	jkinfo@jkchemical.com	China	96815	76

Supplier	Advantage
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Standardpharm Co. Ltd.	58
CONIER CHEM AND PHARMA LIMITED	58
SIMAGCHEM CORP	58
Career Henan Chemica Co	58
Dideu Industries Group Limited	58
Suzhou ARTK Medchem Co., Ltd.	58
DAYANG CHEM (HANGZHOU) CO.,LTD	58
Mainchem Co., Ltd.	58
J & K SCIENTIFIC LTD.	76

155405-81-5(N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid 1,5-dimethyl ester)Related Search:

Pemetrexed Impurity 19 LY 338979 DiMethyl Ester Benzoic acid, 4-(1-methyl-3-oxopropyl)-, methyl ester (9CI) PeMetrexed IMpurity D N-[4-[3-(2,6-DiaMino-1,4-dihydro-4-oxo-5-pyriMidinyl)-3-oxopropyl]benzoyl]-L-glutaMic Acid

3-Butyn-1-ol N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid 1,5-diethyl ester Methyl 4-(4-oxobutyl)benzoate P219490 PeMetrexed EP IMpurity A

Methyl 4-(4-hydroxybut-1-ynyl)benzoate 3-Buten-1-ol Pemetrexed Impurity 18 4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic acid methyl ester 4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pymol[2,3-d]pyrimodin-5-yl)ethyl]benzoic acid

4-[2’-(7’’-Deazaguanine)ethyl]benzoic Acid N-Hydroxysuccinimide Ester Pemetrexed Disodium 2,4-Diamino-6-hydroxypyrimidine

1of4

4-[2-(2-AMino-4-oxo-4,7-Dihydro-3H-pyrrolo[2,3-d]pyriMidine-5-yl)ethyl]-L-GlutaMicAcidDiethylEsterP-TluensulfonicAcidsalt Pemetrexed methyl ester N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid 1,5-dimethyl ester PeMetrexed DiMethyl Ester N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid dimethyl ester Pemetrexed Impurity 21(Pemetrexed Dimethyl Ester) dimethyl (2R)-2-[[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioate (E)-4-(4-((2-amino-6-oxo-1,6-dihydropyrimidin-4-yl)imino)butyl)benzoic acid L-Glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-, 1,5-dimethyl ester 1,5-dimethyl (2S)-2-{[4-(2-{2-amino-4-oxo-1H,7H-pyrrolo[2,3-d]pyrimidin-5-yl}ethyl)phenyl]formamido}pentanedioate imethyl(2R)-2-[[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioate 4-[2-(2-Amino-4-oxo-4,7-Dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-yl)ethyl]benzoic acid diethyl ester sulfonate N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid 1,5-dimethyl ester USP/EP/BP 155405-81-5 Intermediates & Fine Chemicals Pharmaceuticals