2,4,6-Trichlorobenzaldehyde
- CAS No.
- 24473-00-5
- Chemical Name:
- 2,4,6-Trichlorobenzaldehyde
- Synonyms
- 2,4,6-Trichlorobenzaldehyde;Benzaldehyde, 2,4,6-trichloro-
- CBNumber:
- CB42516361
- Molecular Formula:
- C7H3Cl3O
- Molecular Weight:
- 209.46
- MDL Number:
- MFCD12024961
- MOL File:
- 24473-00-5.mol
| Product description | Number | Pack Size | Price |
| 2,4,6-Trichlorobenzaldehyde | T774738 | 100mg | $45 |
| 2,4,6-Trichlorobenzaldehyde | 118354 | 1g | $200 |
| 2,4,6-Trichlorobenzaldehyde | Z4481 | 5g | $220 |
| 2,4,6-Trichlorobenzaldehyde | 2615-5-21 | 1g | $292 |
| 2,4,6-TRICHLOROBENZALDEHYDE 95.00% | HCH0362622 | 5MG | $496.85 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P301+P312-P302+P352-P304+P340-P305+P351+P338 |
| HS Code | 2913000090 |
2,4,6-Trichlorobenzaldehyde price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | T774738 | 2,4,6-Trichlorobenzaldehyde | 24473-00-5 | 100mg | $45 | 2021-12-16 | Buy |
| Matrix Scientific | 118354 | 2,4,6-Trichlorobenzaldehyde | 24473-00-5 | 1g | $200 | 2021-12-16 | Buy |
| AK Scientific | Z4481 | 2,4,6-Trichlorobenzaldehyde | 24473-00-5 | 5g | $220 | 2021-12-16 | Buy |
| SynQuest Laboratories | 2615-5-21 | 2,4,6-Trichlorobenzaldehyde | 24473-00-5 | 1g | $292 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HCH0362622 | 2,4,6-TRICHLOROBENZALDEHYDE 95.00% | 24473-00-5 | 5MG | $496.85 | 2021-12-16 | Buy |
2,4,6-Trichlorobenzaldehyde Chemical Properties,Uses,Production
Uses
2,4,6-Trichlorobenzaldehyde is used in the synthesis of Pydiflumetofen (P999040).
Synthesis
108-70-3
68-12-2
24473-00-5
2.8.2 Synthesis of 2,4,6-trichlorobenzaldehyde (6b): 1,3,5-trichlorobenzene (1.81 g, 10 mmol) was dissolved in anhydrous tetrahydrofuran (36 mL) under dry conditions and stirred at -78°C. The solution was then dissolved in anhydrous tetrahydrofuran (36 mL). N-butyllithium (1.6 M hexane solution, 6.3 mL, 10 mmol) was slowly added dropwise to the above solution over a period of 0.5 h. The solution gradually changed to a light yellow color. After the dropwise addition was completed, stirring was continued at -78 °C for 0.5 hours. Subsequently, anhydrous N,N-dimethylformamide (1.32 mL, 17 mmol) was slowly added dropwise to the reaction mixture and stirring was continued at -80 °C to obtain a light yellow solution. The reaction system was warmed up to -78 °C and kept for 1.5 hours. Upon completion of the reaction, the reaction was quenched with 3N hydrochloric acid solution (36 mL) while keeping the reaction vial at -78 °C and gradually warmed to room temperature to obtain a colorless solution. The reaction mixture was extracted with ethyl acetate (20 mL x 3) and the organic layers were combined and washed sequentially with saturated aqueous sodium bicarbonate solution and brine. The organic layer was dried over anhydrous magnesium sulfate and concentrated under reduced pressure to give the white needle-like solid product 6b (1.99 g, 96% yield). The structure of the product was determined by nuclear magnetic resonance hydrogen spectroscopy (1H NMR, 500 MHz, CDCl3) δ 10.43 (s, 1H), 7.42 (s, 2H); nuclear magnetic resonance carbon spectroscopy (13C NMR, 125 MHz, CDCl3) δ 187.7, 139.4, 137.8, 130.0, 128.8; and high resolution mass spectroscopy (HRMS. ESI) m/z: C7H4Cl3O [M+H]+ calculated value 208.92, measured value 208.9 for confirmation.
References
[1] Bioorganic and Medicinal Chemistry, 2017, vol. 25, # 12, p. 2995 - 3005
[2] Angewandte Chemie - International Edition, 2018, vol. 57, # 11, p. 2869 - 2873
[3] Angew. Chem., 2018, vol. 130, # 11, p. 2919 - 2923,5
[4] Patent: CN108191739, 2018, A. Location in patent: Paragraph 0025; 0026; 0027
[5] Patent: WO2013/30138, 2013, A1. Location in patent: Page/Page column 250; 251
2,4,6-Trichlorobenzaldehyde Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Fluoropharm Co., Ltd. | +86-0571-85586753 +86-13336034509 | sales@fluoropharm.com | China | 1445 | 60 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30229 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Baoji Guokang Healthchem Co., Ltd. | +86-0917-3909592 +86-13892490616 | gksales1@gk-bio.com | China | 9212 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9911 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
| Changzhou Anxuan Chemical Co., Ltd | +86-0519-89882563 +86-18961279162 | andy@anxuanchem.com | China | 4327 | 58 |
| Aromsyn Co., Ltd. | +86-0571-85585865 +8613336024896 | CB@aromsyn.com | China | 19183 | 58 |
View Lastest Price from 2,4,6-Trichlorobenzaldehyde manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2021-07-13 | 2,4,6-Trichlorobenzaldehyde
24473-00-5
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
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- 2,4,6-Trichlorobenzaldehyde
24473-00-5
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
