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3-(2-Guanidino-thiazol-4-yl-methylthio)-propionitrile

3-(2-Guanidino-thiazol-4-yl-methylthio)-propionitrile structure

CAS No.: 76823-93-3

Chemical Name:: 3-(2-Guanidino-thiazol-4-yl-methylthio)-propionitrile

Synonyms: TPN-BASE;Famotidine Impurity 12;Famotidine intermediate;Famotidine Cyanoethyl Impurity;CYANOETHYLTHIOMETHYL-2-THIAZOLYL GUANIDINE;4-[(2-CYANOETHYL)THIO]-2-THIAZOLYL]GUANIDINE;2-[4-(2-CYANOETHYLTHIO)METHYL]THIAZOLYL GUANIDINE;3-(2-Guanidino-4-thiazolylmethulthio)propinitrile;3-(2-GUANIDINOTHIAZOL-4-YLMETHYLTHIO)PROPIONITRILE;3-(2-GUANIDINOTHIAZOL-4-YLMETHYLTHIO)PROPIOUITRILE

CBNumber:: CB4251891

Molecular Formula:: C8H11N5S2

Molecular Weight:: 241.34

MDL Number:: MFCD07369306

MOL File:: 76823-93-3.mol

MSDS File:: SDS

Last updated:2026-06-19 07:28:27

Product description	Number	Pack Size	Price
2-[4-(2-Cyanoethylthio)methyl]thiazolyl guanidine 97%	546879	25g	$435
2-[4-(2-Cyanoethylthio)methyl]thiazolyl guanidine	FC21486	1g	$162.25
2-[4-(2-Cyanoethylthio)methyl]thiazolyl guanidine	FC21486	2g	$259.6
2-[4-(2-Cyanoethylthio)methyl]thiazolyl guanidine	FC21486	5g	$389.4
2-[4-(2-Cyanoethylthio)methyl]thiazolyl guanidine	FC21486	10g	$649
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3-(2-Guanidino-thiazol-4-yl-methylthio)-propionitrile Properties

Melting point	128-132 °C(lit.)
Boiling point	459.7±55.0 °C(Predicted)
Density	1.49±0.1 g/cm3(Predicted)
storage temp.	-20°C Freezer
solubility	DMSO (Slightly), Methanol (Slightly)
pka	8.51±0.70(Predicted)
form	Solid
color	White to Beige
InChI	1S/C8H11N5S2/c9-2-1-3-14-4-6-5-15-8(12-6)13-7(10)11/h5H,1,3-4H2,(H4,10,11,12,13)
InChIKey	FSKYYRZENXOYAP-UHFFFAOYSA-N
SMILES	N\C(N)=N\c1nc(CSCCC#N)cs1
CAS DataBase Reference	76823-93-3(CAS DataBase Reference)
EWG's Food Scores	1-2
FDA UNII	Q26WGP9NWR
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H317
Precautionary statements	P280-P301+P312+P330-P302+P352
PPE	dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Hazard Codes	Xn
Risk Statements	22-43
Safety Statements	22-24-37
WGK Germany	1
Storage Class	11 - Combustible Solids
Hazard Classifications	Acute Tox. 4 Oral Skin Sens. 1
REACH Registrations	Inactive

3-(2-Guanidino-thiazol-4-yl-methylthio)-propionitrile price More Price(26)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	546879	2-[4-(2-Cyanoethylthio)methyl]thiazolyl guanidine 97%	76823-93-3	25g	$435	2026-04-30	Buy
Biosynth	FC21486	2-[4-(2-Cyanoethylthio)methyl]thiazolyl guanidine	76823-93-3	1g	$162.25	2026-06-04	Buy
Biosynth	FC21486	2-[4-(2-Cyanoethylthio)methyl]thiazolyl guanidine	76823-93-3	2g	$259.6	2026-06-04	Buy
Biosynth	FC21486	2-[4-(2-Cyanoethylthio)methyl]thiazolyl guanidine	76823-93-3	5g	$389.4	2026-06-04	Buy
Biosynth	FC21486	2-[4-(2-Cyanoethylthio)methyl]thiazolyl guanidine	76823-93-3	10g	$649	2026-06-04	Buy

Product number	Packaging	Price	Buy
546879	25g	$435	Buy
FC21486	1g	$162.25	Buy
FC21486	2g	$259.6	Buy
FC21486	5g	$389.4	Buy
FC21486	10g	$649	Buy

3-(2-Guanidino-thiazol-4-yl-methylthio)-propionitrile Chemical Properties,Uses,Production

Chemical Properties

Off-White Solid

Uses

Famotidine intermediate.

3-(2-Guanidino-thiazol-4-yl-methylthio)-propionitrile Preparation Products And Raw materials

Raw materials

Amidinothiourea 1,3-Dichloroacetone

Preparation Products

3-(((2-GUANIDINO-4-THIAZOLYL)METHYL)THIO)PROPANIMIDC ACID METHYL ESTER FaMotidine AMide IMpurity

3-(2-Guanidino-thiazol-4-yl-methylthio)-propionitrile Suppliers

Global( 112)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29640	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21585	55
Xiamen AmoyChem Co., Ltd	+86-86-5926051114 +8615060885618	sales@amoychem.com	China	6366	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14332	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58
SIMAGCHEM CORP	+86-5922680277 +86-13806087780	sale@simagchem.com	China	17346	58
Qiuxian Baitai New Material Co., LTD	+8618330912755	sale2@hbyalin.com	China	1658	58
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	eric@witopchemical.com	China	23541	58
AFINE CHEMICALS LIMITED	+86-571-85134551	info@afinechem.com	China	15080	58
Hefei Hirisun Pharmatech Co., Ltd	+8615056975894	shawn@hirisunpharm.com	CHINA	9911	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
Xiamen AmoyChem Co., Ltd	58
Standardpharm Co. Ltd.	58
CONIER CHEM AND PHARMA LIMITED	58
SIMAGCHEM CORP	58
Qiuxian Baitai New Material Co., LTD	58
ANHUI WITOP BIOTECH CO., LTD	58
AFINE CHEMICALS LIMITED	58
Hefei Hirisun Pharmatech Co., Ltd	58

View Lastest Price from 3-(2-Guanidino-thiazol-4-yl-methylthio)-propionitrile manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-06-30	Famotidine Impurity 16 76823-93-3		1kg	98%	1000kg	Shaanxi Dideu New Materials Co. Ltd
	2021-11-15	3-(2-Guanidino-thiazol-4-yl-methylthio)-propionitrile 76823-93-3	$98.00	100g	99%	500ton/Month	Qiuxian Baitai New Material Co., LTD

Famotidine Impurity 16
76823-93-3
98%
Shaanxi Dideu New Materials Co. Ltd

3-(2-Guanidino-thiazol-4-yl-methylthio)-propionitrile
76823-93-3
$98.00
99%
Qiuxian Baitai New Material Co., LTD

3-(2-Guanidino-thiazol-4-yl-methylthio)-propionitrile Spectrum

3-(2-Guanidino-thiazol-4-yl-methylthio)-propionitrile(76823-93-3)¹HNMR 3-(2-Guanidino-thiazol-4-yl-methylthio)-propionitrile(76823-93-3)IR

76823-93-3(3-(2-Guanidino-thiazol-4-yl-methylthio)-propionitrile)Related Search:

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Fosthiazate Methylchloroisothiazolinone/methylisothiazolinone mixture (MCIT/MIT) Dicyandiamide N-DesaMinosulfonyl-N-cyano FaMotidine Famotidine EP Impurity A

2-Methyl-4-isothiazolin-3-one FAMOTIDINE RELATED COMPOUND B Sulfamide [3-[[[2-(DiaMinoMethyleneaMino)-4-thiazolyl]Methyl]thio]propionyl]sulfaMide Hydrochloride (FaMotidine IMpurity) 2-(4-(CHLOROMETHYL)THIAZOL-2-YL)GUANIDINE

3-[2-(Diaminomethyleneamino)-1,3-thiazol-4-ylmethylsulphinyl]-N-sulphamoyl propanamide Bis[(2-guanidino-4-thiazolyl)methyl]disulfide (S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride

1of4

TPN-BASE (4-(((2-Cyanoethyl)thio)methyl)-2-thia-zolyl)guanidine [4-[[(2-cyanoethyl)thio]methyl]-2-thiazolyl]-guanidin N-[4-(2-CYANO-ETHYLSULFANYLMETHYL)-THIAZOL-2YL]-GUANIDINE N-[4-[(2-CYANOETHYL)THIO]METHYL]-2THIAZOLYL]GUANIDINE CYANOETHYLTHIOMETHYL-2-THIAZOLYL GUANIDINE 2-[4-(2-CYANOETHYLTHIO)METHYL]THIAZOLYL GUANIDINE 3-(2-GUANIDINOTHIAZOL-4-YLMETHYLTHIO)PROPIONITRILE 2-[4-[(2-cyanoethylthio)methyl]-2-thiazolyl]guanidine 1-{4-[(2-Cyanoethyl)thiomethyl]thiazol-2-yl}guanidine 3-(2-GUANIDINOTHIAZOL-4-YLMETHYLTHIO)PROPIOUITRILE 3-((2-Guanidino-4-thiazolyl)methyl thiopropanenitrile 3-(2-GUANIDINOTHIAZOL-4-YLMETHYLTHIO)PROPIOUITRILE ,GB 4-[(2-CYANOETHYL)THIO]-2-THIAZOLYL]GUANIDINE 4-[(2-CYANOETHYL)THIO]-2-THIAZOLYL]GUANIDINEFAMOTIDINE HCL 3-(2-(diaminomethyleneamino)thiazol-4-ylmethylthio)propionitrile (4-(((2YANOETHYL)THIO)METHYL)-2-THIAZOLYL)GUANIDINE Famotidine Impurity 12 Famotidine intermediate Famotidine Cyanoethyl Impurity Guanidine, N-[4-[[(2-cyanoethyl)thio]methyl]-2-thiazolyl]- 3-(2-Guanidino-4-thiazolylmethulthio)propinitrile 3-(2-(diaminomethyleneamino)thiazol-4-yl)methylthio)propiono... Guanidine,[4-[[(2-cyanoethyl)thio]methyl]-2-thiazolyl]- (9CI) 3-(((2-((Diaminomethyl) amino)-4-thiazolyl)-methyl) thio) propionitrile. (T.P.N. Base, an intermediate of Famotidine) 3-(2-(diaminomethyleneamino)thiazol-4-yl)methylthio)propiononitrile 76823-93-3 C8H11N5S2 C9H13N5S2 Building Blocks Heterocyclic Building Blocks Thiazoles Building Blocks Heterocyclic Building Blocks Thiazoles Heterocycles Intermediates Intermediates & Fine Chemicals Pharmaceuticals Sulfur & Selenium Compounds Building Blocks C8 to C9 Chemical Synthesis Heterocyclic Building Blocks