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ChemicalBook >> CAS DataBase List >>4-chloro-6-methoxyquinolin-7-ol

4-chloro-6-methoxyquinolin-7-ol

4-chloro-6-methoxyquinolin-7-ol Structure
4-chloro-6-methoxyquinolin-7-ol structure
CAS No.
205448-31-3
Chemical Name:
4-chloro-6-methoxyquinolin-7-ol
Synonyms
4-Chloro-6-Methoxy-7-quinolinol;Bedaquiline Impurity 133;4-chloro-6-methoxyquinolin-8-ol;4-chloro-6-methoxyquinolin-7-ol;7-Quinolinol, 4-chloro-6-methoxy-;4-chloro-6-methoxy-1H-quinolin-7-one;4-Chloro-7-hydroxy-6-Methoxyquinolin;4-Chloro-7-hydroxy-6-methoxyquinoline;4-Chloro-6-methoxy-7-hydroxyquinoline
CBNumber:
CB42526056
Molecular Formula:
C10H8ClNO2
Molecular Weight:
209.63
MDL Number:
MFCD13191788
MOL File:
205448-31-3.mol
MSDS File:
SDS
Last updated:2026-05-28 02:24:46
Product description Number Pack Size Price
4-Chloro-6-methoxyquinolin-7-ol Asreported 268991 2g $470
4-Chloro-6-methoxyquinolin-7-ol Asreported 268991 5g $691
4-Chloro-6-methoxyquinolin-7-ol Asreported 268991 10g $984
4-Chloro-6-methoxyquinolin-7-ol Asreported 268991 25g $1649
4-Chloro-6-methoxyquinolin-7-ol Asreported 268991 50g $2726
More product size
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4-chloro-6-methoxyquinolin-7-ol Properties

Boiling point 353℃
Density 1.386
Flash point 168℃
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka 8.41±0.40(Predicted)
form solid
color White to light brown
InChI InChI=1S/C10H8ClNO2/c1-14-10-4-6-7(11)2-3-12-8(6)5-9(10)13/h2-5,13H,1H3
InChIKey NKWZPFHSWLSOON-UHFFFAOYSA-N
SMILES N1C2C(=CC(OC)=C(O)C=2)C(Cl)=CC=1

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H319-H335-H302+H312+H332-H315
Precautionary statements  P261-P271-P280
HS Code  2933499090

4-chloro-6-methoxyquinolin-7-ol price More Price(76)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 268991 4-Chloro-6-methoxyquinolin-7-ol Asreported 205448-31-3 2g $470 2026-06-03 Buy
Usbiological 268991 4-Chloro-6-methoxyquinolin-7-ol Asreported 205448-31-3 5g $691 2026-06-03 Buy
Usbiological 268991 4-Chloro-6-methoxyquinolin-7-ol Asreported 205448-31-3 10g $984 2026-06-03 Buy
Usbiological 268991 4-Chloro-6-methoxyquinolin-7-ol Asreported 205448-31-3 25g $1649 2026-06-03 Buy
Usbiological 268991 4-Chloro-6-methoxyquinolin-7-ol Asreported 205448-31-3 50g $2726 2026-06-03 Buy
Product number Packaging Price Buy
268991 2g $470 Buy
268991 5g $691 Buy
268991 10g $984 Buy
268991 25g $1649 Buy
268991 50g $2726 Buy

4-chloro-6-methoxyquinolin-7-ol Chemical Properties,Uses,Production

Chemical Properties

Brown solid

Synthesis

7-Benzyloxy-4-chloro-6-methoxy-quinoline

286371-49-1

4-chloro-6-methoxyquinolin-7-ol

205448-31-3

General procedure for the synthesis of 7-hydroxy-4-chloro-6-methoxyquinoline from 7-(benzyloxy)-4-chloro-6-methoxyquinoline: the compound 7-(benzyloxy)-4-chloro-6-methoxyquinoline (16 g, 53.37 mmol) was dissolved in trifluoroacetic acid (100 mL), and methanesulfonic acid (6.1 mL, 93.94 mmol) was added in one go. The reaction mixture was stirred under reflux conditions for 3 hours and subsequently cooled to room temperature. The solvent was removed by evaporation and the pH of the residue was adjusted to 7 with 2.5 N sodium hydroxide solution.The resulting solid was crushed into small pieces and the mixture was stirred vigorously for 2 hr. The solid was collected by filtration and dried under high vacuum to give 7-hydroxy-4-chloro-6-methoxyquinoline (11.3 g, yield = 100%) as a light brown solid.

References

[1] Journal of Medicinal Chemistry, 2008, vol. 51, # 18, p. 5766 - 5779
[2] Patent: US2014/235634, 2014, A1. Location in patent: Paragraph 0356; 0362
[3] Patent: CN106749231, 2017, A. Location in patent: Paragraph 0080; 0081; 0092; 0093

4-chloro-6-methoxyquinolin-7-ol Preparation Products And Raw materials

Raw materials

7-benzyloxy-4-chloro-6-methoxyquinoline hydrochloride 7-Benzyloxy-4-chloro-6-methoxy-quinoline Thioanisole

Preparation Products

4-chloro-6-methoxyquinolin-7-ol Suppliers

Global( 146)Suppliers
Supplier Tel Email Country ProdList Advantage
Nanjing ChemLin Chemical Industry Co., Ltd. 		025-83697070 product@chemlin.com.cn CHINA 3009 60
Shanghai Arbor Chemical Co., Ltd. 		021-60451682 act@arborchemical.com CHINA 904 58
Changzhou Ansciep Chemical Co., Ltd. 		+86 519 86305871 sales@ansciepchem.com CHINA 4241 58
Accela ChemBio Inc. 		+1-858-6993322 info@accelachem.com United States 21193 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49979 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29792 58
Fuxin Pharmaceutical 		+86-021-021-50872116 +8613122107989 contact@fuxinpharm.com China 10000 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		+8613580539051 joe@yuhengpharm.com CHINA 21142 58
Neostar United (Changzhou) Industrial Co., Ltd. 		+86-0519-85551759 +8613506123987 marketing1@neostarunited.com China 8828 58
Supplier Advantage
Nanjing ChemLin Chemical Industry Co., Ltd. 		60
Shanghai Arbor Chemical Co., Ltd. 		58
Changzhou Ansciep Chemical Co., Ltd. 		58
Accela ChemBio Inc. 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
career henan chemical co 		58
Fuxin Pharmaceutical 		58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		58
Neostar United (Changzhou) Industrial Co., Ltd. 		58

View Lastest Price from 4-chloro-6-methoxyquinolin-7-ol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-chloro-6-methoxyquinolin-7-ol pictures 2025-04-04 4-chloro-6-methoxyquinolin-7-ol
205448-31-3
 1KG 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
4-chloro-6-methoxyquinolin-7-ol pictures 2021-07-02 4-chloro-6-methoxyquinolin-7-ol
205448-31-3
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
4-chloro-6-methoxyquinolin-7-ol pictures 2020-01-08 4-chloro-6-methoxyquinolin-7-ol
205448-31-3
 $2.00 1KG 98% 100g , 1kg, 5kg , 50kg Career Henan Chemical Co

4-chloro-6-methoxyquinolin-7-ol Spectrum

4-chloro-6-methoxyquinolin-7-ol(205448-31-3)1HNMR

205448-31-3(4-chloro-6-methoxyquinolin-7-ol)Related Search:

λ-Cyhalothrin 2-Formylfuran-5-boronic acid EUGENOL ACETATE diloxanide
4-chloro-6-methoxyquinolin-7-ol 4-Chloro-7-hydroxy-6-methoxyquinoline 4-Chloro-7-hydroxy-6-Methoxyquinolin 7-Quinolinol, 4-chloro-6-methoxy- 4-Chloro-6-methoxy-7-hydroxyquinoline 4-chloro-6-methoxy-1H-quinolin-7-one 4-chloro-6-methoxyquinolin-8-ol Bedaquiline Impurity 133 4-Chloro-6-Methoxy-7-quinolinol 205448-31-3 5448-31-3