Genistein-4,6,2',3',5',6'-d6

CAS No.
Chemical Name:
Genistein-4,6,2',3',5',6'-d6
Synonyms
Genistein-4,6,2',3',5',6'-d6
CBNumber:
CB42551065
Molecular Formula:
C15H10O5
Molecular Weight:
270.2369
MDL Number:
MOL File:
Mol file

Genistein-4,6,2',3',5',6'-d6 Chemical Properties,Uses,Production

Chemical Properties

Light Yellow Solid

Uses

Labelled Genistein (G350000). Exhibits specific inhibitory activity against tyrosine kinases,including autophosphorylation of epidermal growth factor receptor kinase (IC50 - 2.6uM). Also inhibits other protein kinases through competitive inhibition of ATP. Inhibits tumor cell proliferation and induces tumor cell differentiation. Produces cell-cycle arrest and apoptosis in Jurat T-leukemia cells. However, it prevents anti-CD3 monoclonal antibody-induced thymic apoptosis. Genistein also inhibits topoisomerase II activity in vitro. Genistein has also been shown to inhibit the action of GABA on recombinant GABAA receptors 2. uv(max)ethanol: 262.5 nm (e= 138). moderately sol. in hot alcohol

Genistein-4,6,2',3',5',6'-d6 Preparation Products And Raw materials

Raw materials

Preparation Products

Genistein-4,6,2',3',5',6'-d6 Suppliers

Global( 1)Suppliers
Supplier Tel Email Country ProdList Advantage
Toronto Research Chemicals -- info@trc-canada.com Canada 6038 71
Supplier Advantage
Toronto Research Chemicals 71
Genistein-4,6,2',3',5',6'-d6 C15H4D6O5 Isotope Labelled Compounds Tyrosine Kinase Inhibitors Inhibitors