(2-Methylbenzo[d]oxazol-6-yl)Methanol
![(2-Methylbenzo[d]oxazol-6-yl)Methanol Structure](CAS/20180713/GIF/136663-40-6.gif)
- CAS No.
- 136663-40-6
- Chemical Name:
- (2-Methylbenzo[d]oxazol-6-yl)Methanol
- Synonyms
- 2-Methylbenzoxazole-6-methanol;2-methyl-6-benzoxazolemethanol;6-Benzoxazolemethanol, 2-methyl-;(2-Methylbenzo[d]oxazol-6-yl)Methanol;(2-methyl-1,3-benzoxazol-6-yl)methanol;(2-methyl-1,3-benzoxazol-6-yl)methanol - [M82543]
- CBNumber:
- CB42551797
- Molecular Formula:
- C9H9NO2
- Molecular Weight:
- 163.17
- MDL Number:
- MFCD22019828
- MOL File:
- 136663-40-6.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| (2-Methylbenzo[d]oxazol-6-yl)methanol | 291884 | 250.00mg | $66 |
| (2-Methylbenzo[d]oxazol-6-yl)methanol | 291884 | 1.00g | $146 |
| (2-Methylbenzo[d]oxazol-6-yl)methanol | 291884 | 5.00g | $708 |
| (2-methyl-1,3-benzoxazol-6-yl)methanol 95% | M82543 | 100mg | $37 |
| (2-methyl-1,3-benzoxazol-6-yl)methanol 95% | M82543 | 250mg | $70 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P305+P351+P338-P337+P313-P261-P271-P304+P340-P312-P403+P233-P405-P501 |
(2-Methylbenzo[d]oxazol-6-yl)Methanol price More Price(47)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 291884 | (2-Methylbenzo[d]oxazol-6-yl)methanol | 136663-40-6 | 250.00mg | $66 | 2026-05-19 | Buy |
| Matrix Scientific | 291884 | (2-Methylbenzo[d]oxazol-6-yl)methanol | 136663-40-6 | 1.00g | $146 | 2026-05-19 | Buy |
| Matrix Scientific | 291884 | (2-Methylbenzo[d]oxazol-6-yl)methanol | 136663-40-6 | 5.00g | $708 | 2026-05-19 | Buy |
| Synthonix | M82543 | (2-methyl-1,3-benzoxazol-6-yl)methanol 95% | 136663-40-6 | 100mg | $37 | 2026-05-06 | Buy |
| Synthonix | M82543 | (2-methyl-1,3-benzoxazol-6-yl)methanol 95% | 136663-40-6 | 250mg | $70 | 2026-05-06 | Buy |
(2-Methylbenzo[d]oxazol-6-yl)Methanol Chemical Properties,Uses,Production
Uses
2-Methyl-6-benzoxazolemethanol is used in the preparation of thiazolones which are useful for inhibiting the activity and function of PI3 kinases.
Synthesis
136663-23-5
![(2-Methylbenzo[d]oxazol-6-yl)Methanol](/CAS/20180713/GIF/136663-40-6.gif)
136663-40-6
General procedure for the synthesis of (2-methylbenzo[d]oxazol-6-yl)methanol from methyl 2-methylbenzo[d]oxazole-6-carboxylate: to a solution of methyl 2-methylbenzo[d]oxazole-6-carboxylate (25 g, 0.13 mol) in tetrahydrofuran (THF, 500 mL) was slowly added lithium aluminum hydride (LiAlH4, 4.81 g, at -20 °C. 130 mL, 1 M THF solution, 0.13 mol, 1 equiv). The reaction mixture was gradually warmed to room temperature and stirred overnight. Upon completion of the reaction, the reaction was quenched by the careful addition of water (5 mL), followed by the addition of 1M sodium hydroxide (NaOH) solution (5 mL), then water (15 mL), and continued stirring for 15 minutes at room temperature. The reaction mixture was filtered and the filtrate was concentrated under reduced pressure and purified by column chromatography (eluent ratio of 1:3 ethyl acetate:dichloromethane) to afford 12.5 g of the target product (2-methylbenzo[d]oxazol-6-yl)methanol in 58% yield. The product was confirmed by 1H-NMR (CDCl3): δ 2.64 (s, 3H), 4.82 (s, 2H), 7.29 (d, 1H, J=8Hz), 7.53 (s, 1H), 7.62 (d, 1H, J=8Hz). lC-MS (m/z) = 164.2 ([M+H]+).
References
[1] Patent: WO2005/82901, 2005, A1. Location in patent: Page/Page column 33; 61
[2] Patent: WO2007/103755, 2007, A2. Location in patent: Page/Page column 51; 83
(2-Methylbenzo[d]oxazol-6-yl)Methanol Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29812 | 58 |
| Wuxi Rejoys chemical Technology Co., Ltd. | 0510-86103381 | sales@rejoyschem.com | CHINA | 976 | 58 |
| Blocksynth Pharmaceutical Technology Co.,Ltd | 0086-19817745290; 19817745290 | bd@blocksynth.com | China | 5973 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20120 | 58 |
| SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | cooperation@kean-chem.com | China | 40066 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39927 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131956 | 58 |
| ROSEWA HOLDING GROUP CO.,LIMITED | +86-023-62871537 | sales@rosewachem.com | China | 2812 | 58 |
| ShangHai AmK Pharmaceutical Technology Co., Ltd. | 微信 17321281695 18019252918 | sale@amkchem.com | China | 14982 | 55 |
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![(2-Methylbenzo[d]oxazol-6-yl)Methanol pictures](https://img.chemicalbook.com/ProductImageEN/2018-8/Small/cbdd3ada-bc7a-4401-9c6e-84c6ccc855f0.png) |
2019-07-06 | (2-Methylbenzo[d]oxazol-6-yl)Methanol
136663-40-6
|
$1.00 | 1KG | 96% | 500kg | Career Henan Chemical Co |
-
- (2-Methylbenzo[d]oxazol-6-yl)Methanol
136663-40-6
- $1.00
- 96%
- Career Henan Chemical Co
