4-hydroxy Nonenal Mercapturic Acid-d3
- CAS No.
- Chemical Name:
- 4-hydroxy Nonenal Mercapturic Acid-d3
- Synonyms
- 4-hydroxy Nonenal Mercapturic Acid-d3
- CBNumber:
- CB42590040
- Molecular Formula:
- C14H22D3NO5S
- Molecular Weight:
- 322.435485334
- MDL Number:
- MOL File:
- Mol file
4-hydroxy Nonenal Mercapturic Acid-d3 price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 9000348 | 4-hydroxy Nonenal Mercapturic Acid-d3 ≥99%deuteratedforms(d1- |
50μg | $121 | 2026-04-30 | Buy | |
| Cayman Chemical | 9000348 | 4-hydroxy Nonenal Mercapturic Acid-d3 ≥99%deuteratedforms(d1- |
100μg | $214 | 2026-04-30 | Buy | |
| Cayman Chemical | 9000348 | 4-hydroxy Nonenal Mercapturic Acid-d3 ≥99%deuteratedforms(d1- |
500μg | $956 | 2026-04-30 | Buy | |
| ChemScene | CS-0716186 | 4-Hydroxy nonenal mercapturic acid-d3 | 1mg | $608 | 2026-06-04 | Buy | |
| TRC | H296812 | 4-HydroxyNonenalMercapturicAcid-d3 | 2.5mg | $475 | 2021-12-16 | Buy |
4-hydroxy Nonenal Mercapturic Acid-d3 Chemical Properties, Uses, Production
Description
4-hydroxy Nonenal mercapturic acid-d3 contains three deuterium atoms at the terminal methyl position. It is intended for use as an internal standard for the quantification of 4-HNE mercapturic acid by GC- or LC-mass spectrometry. Peroxidation of common ω-6 polyunsaturated fatty acids (PUFAs) such as linoleic acid, DGLA, and arachidonic acid can give rise to 4-HNE. 4-HNE is cleared rapidly from the plasma and undergoes enterohepatic circulation as a glutathione conjugate in the rat.1 About two thirds of an administered dose of 4-HNE is excreted within 48 hours in the urine, primarily in the form of mercapturic acid conjugates.2 The C-1 aldehyde of 4-HNE is reduced to an alcohol in about half of these metabolites. The remainder are C-1 aldehydes or have been oxidized to C-1 carboxylic acids. These aldehydes and carboxylic acids can also form γ-lactols and γ-lactones, respectively, producing at least four or five end urinary metabolites of 4-HNE in vivo.WARNING This product is not for human or veterinary use.
References
[1] ALEXIA LAURENT. Analysis in the Rat of 4-Hydroxynonenal Metabolites Excreted in Bile: Evidence of Enterohepatic Circulation of These Byproducts of Lipid Peroxidation[J]. Chemical Research in Toxicology, 1999, 12 10: 887-894. DOI: 10.1021/tx9900425
[2] JACQUES ALARY. Mercapturic Acid Conjugates as Urinary End Metabolites of the Lipid Peroxidation Product 4-Hydroxy-2-nonenal in the Rat[J]. Chemical Research in Toxicology, 1995, 8 1: 34-39. DOI: 10.1021/tx00043a004
4-hydroxy Nonenal Mercapturic Acid-d3 Preparation Products And Raw materials
Raw materials
Preparation Products
4-hydroxy Nonenal Mercapturic Acid-d3 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ChemeGen | 18818260767 | 2625930290@qq.com | China | 6966 | 58 |
| LGC Science (Shanghai) Ltd. | 17717235263 | offer.de@lgcgroup.com | China | 19036 | 58 |
| Shanghai Haohong Scientific Co., Ltd. | 400-8210725 4008210725 | malulu@leyan.com | China | 39319 | 58 |
| Supplier | Advantage |
|---|---|
| ChemeGen | 58 |
| LGC Science (Shanghai) Ltd. | 58 |
| Shanghai Haohong Scientific Co., Ltd. | 58 |
