7(R)-Maresin 1
- CAS No.
- 1268720-28-0
- Chemical Name:
- 7(R)-Maresin 1
- Synonyms
- Maresin 1;7(R)-Maresin 1;Lactic acid impurity 102;HLHYXXBCQOUTGK-FHCQLJOMSA-N;7(R)-Maresin 1 Exclusive;Maresin 1(solution in ethanol);4,8,10,12,16,19-Docosahexaenoic acid, 7,14-dihydroxy-, (4Z,7R,8E,10E,12Z,14S,16Z,19Z)-
- CBNumber:
- CB42590080
- Molecular Formula:
- C22H32O4
- Molecular Weight:
- 360.49
- MDL Number:
- MOL File:
- 1268720-28-0.mol
- MSDS File:
- SDS
| Boiling point | 559.4±50.0 °C(Predicted) |
|---|---|
| Density | 1.048±0.06 g/cm3(Predicted) |
| storage temp. | Store at -80°C, protect from light |
| solubility | DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 0.05 mg/ml |
| form | Liquid |
| pka | 4.58±0.10(Predicted) |
| color | Colorless to light yellow |
| FDA UNII | M82H7JW4HK |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| NFPA 704 |
|
7(R)-Maresin 1 price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 10878 | Maresin 1 ≥95% | 1268720-28-0 | 10μg | $87 | 2026-04-30 | Buy |
| Cayman Chemical | 10878 | Maresin 1 ≥95% | 1268720-28-0 | 25μg | $207 | 2026-04-30 | Buy |
| Cayman Chemical | 10878 | Maresin 1 ≥95% | 1268720-28-0 | 50μg | $392 | 2026-04-30 | Buy |
| Cayman Chemical | 10878 | Maresin 1 ≥95% | 1268720-28-0 | 100μg | $696 | 2026-04-30 | Buy |
| Biosynth | TAC72028 | Maresin 1 | 1268720-28-0 | 10ug | $324.5 | 2026-06-05 | Buy |
7(R)-Maresin 1 Chemical Properties, Uses, Production
Uses
Maresin 1-d5 is the deuterium labeled Maresin 1. Maresin 1, produced by human Mφs from endogenous docosahexaenoic acid (DHA) and a specialized proresolving mediator, stimulates intracellular [Ca2+] and secretion. Maresin 1 possesses anti-inflammatory activity[1][2][3].
Definition
ChEBI: (7R,14S)-dihydroxy-(4Z,8E,10E,12Z,16Z,19Z)-docosahexaenoic acid is a dihydroxydocosahexaenoic acid that is (4Z,8E,10E,12Z,16Z,19Z)-docosahexaenoic acid in which the two hydroxy substituents are located at the 7R- and 14S-positions. It has a role as an anti-inflammatory agent, a human xenobiotic metabolite, a hepatoprotective agent and a specialised pro-resolving mediator. It is a dihydroxydocosahexaenoic acid and a secondary allylic alcohol. It is functionally related to an all-cis-docosa-4,7,10,13,16,19-hexaenoic acid.
References
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. DOI:10.1177/1060028018797110
[2] Markus V Olsen, et al. Maresin 1, a Specialized Proresolving Mediator, Stimulates Intracellular [Ca 2+ ] and Secretion in Conjunctival Goblet Cells. J Cell Physiol. 2020 Jun 8. DOI:10.1002/jcp.29846
[3] Macrophage Proresolving Mediator Maresin 1 Stimulates Tissue Regeneration and Controls Pain DOI:10.1096/fj.11-201442
[4] Rodrigo Marcon, et al. Maresin 1, a Proresolving Lipid Mediator Derived From omega-3 Polyunsaturated Fatty Acids, Exerts Protective Actions in Murine Models of Colitis. J Immunol. 2013 Oct 15;191(8):4288-98. DOI:10.4049/jimmunol.1202743
7(R)-Maresin 1 Preparation Products And Raw materials
Raw materials
Preparation Products
7(R)-Maresin 1 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| LETOPHARM LIMITED | +86-21-5821 5861 | sales@letopharm.com | China | 2374 | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 400-920-5774 | sales@glpbio.cn | China | 6705 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| Shanghai Jiegu Biotechnology Co., Ltd. | 021-51698675 | sales@jiejiegroup.com | China | 8195 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8137 | 58 |
| Shanghai Universal Biotech Co.,Ltd | 15921930842 15921930842 | yh-wang@univ-bio.com | China | 25030 | 58 |
| amyjet | 4006800868;027-59626688 18771149750 | sales@amyjet.com | China | 2909 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 5985 | 58 |
