ChemicalBook >> CAS DataBase List >>1-Bromo-4-iodobenzene

1-Bromo-4-iodobenzene

1-Bromo-4-iodobenzene structure

CAS No.: 589-87-7

Chemical Name:: 1-Bromo-4-iodobenzene

Synonyms: P-BROMOIODOBENZENE;4-BROMOIODOBENZENE;4-BroMoiodoben;p-Bromiodobenzene;4-IODOBROMOBENZENE;p-Iodobromobenzene;4- Bromiodobenzene;1-Brom-4-iodbenzol;1-BROMO-IODOBENZENE;4-Bromophenyl iodide

CBNumber:: CB4266086

Molecular Formula:: C6H4BrI

Molecular Weight:: 282.9

MDL Number:: MFCD00001051

MOL File:: 589-87-7.mol

MSDS File:: SDS

Last updated:2026-04-10 10:27:15

Product description	Number	Pack Size	Price
1-Bromo-4-iodobenzene 98%	238090	5g	$33.1
1-Bromo-4-iodobenzene 98%	238090	25g	$156
1-Bromo-4-iodobenzene	B0604	25G	$64
1-Bromo-4-iodobenzene	B0604	250G	$383
1-Bromo-4-iodobenzene	B683675	5g	$55
More product size

Request For Quotation

1-Bromo-4-iodobenzene Properties

Melting point	89-91 °C(lit.)
Boiling point	120-122 °C14 mm Hg(lit.)
Density	2.2236 (rough estimate)
refractive index	1.6618 (estimate)
Flash point	120-122°C/14mm
storage temp.	Store below +30°C.
solubility	0.008g/l
form	Crystalline Powder, Crystals or Needles
color	White to brown
Water Solubility	Insoluble in water.
Sensitive	Light Sensitive
BRN	1904545
Henry's Law Constant	1.5×10^-2 mol/(m³Pa) at 25℃, Ebert et al. (2023)
InChI	1S/C6H4BrI/c7-5-1-3-6(8)4-2-5/h1-4H
InChIKey	UCCUXODGPMAHRL-UHFFFAOYSA-N
SMILES	Brc1ccc(I)cc1
CAS DataBase Reference	589-87-7(CAS DataBase Reference)
FDA UNII	R9LDG2XS7C
NIST Chemistry Reference	Benzene, 1-bromo-4-iodo-(589-87-7)
EPA Substance Registry System	Benzene, 1-bromo-4-iodo- (589-87-7)
UNSPSC Code	12352101
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319

Precautionary statements

P302+P352-P305+P351+P338

PPE

dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36-37/39

WGK Germany

Hazard Note

Harmful/Light Sensitive

TSCA

TSCA listed

HazardClass

IRRITANT, LIGHT SENSITIVE, IRRITANT-HARMFUL

HS Code

29036990

Storage Class

11 - Combustible Solids

Hazard Classifications

Eye Irrit. 2
Skin Irrit. 2

NFPA 704

	1
2		0

1-Bromo-4-iodobenzene price More Price(37)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	238090	1-Bromo-4-iodobenzene 98%	589-87-7	5g	$33.1	2026-03-19	Buy
Sigma-Aldrich	238090	1-Bromo-4-iodobenzene 98%	589-87-7	25g	$156	2026-03-19	Buy
TCI Chemical	B0604	1-Bromo-4-iodobenzene	589-87-7	25G	$64	2026-03-19	Buy
TCI Chemical	B0604	1-Bromo-4-iodobenzene	589-87-7	250G	$383	2026-03-19	Buy
TRC	B683675	1-Bromo-4-iodobenzene	589-87-7	5g	$55	2021-12-16	Buy

Product number	Packaging	Price	Buy
238090	5g	$33.1	Buy
238090	25g	$156	Buy
B0604	25G	$64	Buy
B0604	250G	$383	Buy
B683675	5g	$55	Buy

1-Bromo-4-iodobenzene Chemical Properties,Uses,Production

Synthesis methods

Industrial parabromoaniline is as raw material, by diazotization, iodo-synthesis of bromo iodobenzene. Preferred synthesis conditions: firstly 0.02mol parabromoaniline is dissolved in a mass fraction of 20% sulfuric acid medium, then reacts with 0.021molNaNO2 to generate bromophenyl diazonium sulfate at-10℃, and then chloroform and 0.021molKI is added into solution to process iodination reaction, after simple treatment bromo-iodobenzene crude product (which the bromo-iodobenzene HPLC purity 98.4%) is obtained, total yield after purification is 80%, increases by 15% than before improved. The product processes structural characterization by IR and 1HNMR. The improved method can greatly improve the purity of the crude product, this avoids the trouble of going through the column, this method is safe and easy to operate, easy to control the process, cost is lower, it is more suitable for the preparation of 1-Bromo-4-iodobenzene.
Unit: Heilongjiang University of Chemistry and Materials Science
Author: Guo Jing Bai Xuefeng Lvhong Fei

Uses

1. 1-Bromo-4-iodobenzene is used for organic synthesis.
2. Used as substrate for copper-free Sonogashira coupling reaction in aqueous acetone.
3. For the synthesis of β,β-dibromostyrene.

Chemical Properties

white to brown cryst. powder, crystals or needles

Uses

suzuki reaction

Uses

1-Bromo-4-iodobenzene has been employed:

as reagent for in situ desilylation and coupling of silylated alkynes
as starting reagent in the total syntheses of ent-conduramine A and ent-7-deoxypancratistatin (alkaloids)
as substrate in copper-free Sonogashira coupling in aqueous acetone
in synthesis of β,β,dibromostyrenes

General Description

Vapour pressure as a function of temperature for 1-bromo-4-iodobenzene has been studied using a diaphragm manometer and torsion mass-loss effusion.

Synthesis

The p-bromoiodobenzene was synthesized by diazotization and iodination using industrial p-bromoaniline as raw material. The better synthesis conditions: firstly, 0.02 mol of p-bromoaniline was dissolved in 20% sulfuric acid, and reacted with 0.021 mol of NaNO2 to form p-bromobenzene diazonium sulfate at -10 , and then chloroform and 0.021 mol of KI were added to the solution for iodine substitution, and then p-bromoiodobenzene was obtained as a crude product after simple post-processing (in which the purity was 98.4%), and the total yield after purification was 80%, which was better than that of the improved synthesis. 98.4%), and the total yield reached 80% after purification, which was 15% higher than that before improvement. The product was structurally characterized by IR and 1HNMR. The improved method greatly improved the purity of the crude product, avoided the trouble of passing through the column, was easy and safe to operate, easy to control the process, low cost, and more suitable for the preparation of p-bromoiodobenzene.
UnitSchool of Chemistry, Chemical Engineering and Materials, Heilongjiang University
AuthorGuo Jing, Bai Xuefeng, Lv Hongfei

1-Bromo-4-iodobenzene synthesis

Synthesis of 1-Bromo-4-iodobenzene from 4-BROMOBENZENEDIAZONIUM TETRAFLUOROBORATE

1-Bromo-4-iodobenzene Preparation Products And Raw materials

Raw materials

Preparation Products

4-Bromophenoxybenzene (E)-METHYL 3-(4-BROMOPHENYL)ACRYLATE 4-Bromobenzaldehyde 1-(4-Bromophenyl)-naphthlene 4-(NAPHTHALEN-2-YL)PHENYLBORONIC ACID

4-BROMOBENZENESULFONIC ACID MONOHYDRATE 1-Bromo-4-propylbenzene 2-(4-bromophenyl)-1,3,4-oxadiazole (9-(4-BROMOPHENYL))-9H-CARBAZOLE 1 4-BIS(DIPHENYLAMINO)BENZENE

4-BROMODIPHENYLMETHANE METHYL 4'-BROMO[1,1'-BIPHENYL]-4-CARBOXYLATE 1,4-BIS(PHENYLETHYNYL)BENZENE 4-(P-IODOPHENYL)BUTYRIC ACID 9-(1,1-bipheny)-4-yl-3-(4-broMophenyl)carbazole

1of3

1-Bromo-4-iodobenzene Suppliers

Global( 650)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Nanjing Shunxiang Pharmaceutical Technology Co.,Ltd.	+86-025-86819862 +86-13913839793	sales@jinchemical.com	China	29	58
Shandong Dinghao Biological Technology Co. LTD	+86-86-18300239 +8618300239268	sales@sddhpharm.com	China	101	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8738	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-86-13131129325 +8613131129325	sales1@chuanghaibio.com	China	5235	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20124	58
Hebei Zhuanglai Chemical Trading Co Ltd	+86-16264648883	niki@zlchemi.com	China	7245	58
Springchem New Material Technology Co.,Limited	+86-021-62885108 +8613917661608	info@spring-chem.com	China	2068	57
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29640	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	13815	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21591	55

Supplier	Advantage
Nanjing Shunxiang Pharmaceutical Technology Co.,Ltd.	58
Shandong Dinghao Biological Technology Co. LTD	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Hebei Chuanghai Biotechnology Co,.LTD	58
Henan Fengda Chemical Co., Ltd	58
Hebei Zhuanglai Chemical Trading Co Ltd	58
Springchem New Material Technology Co.,Limited	57
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55

View Lastest Price from 1-Bromo-4-iodobenzene manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-04-29	1-Bromo-4-iodobenzene 589-87-7	US $25.00 / KG	1KG	98%+	300MT/year	Speranza Chemical Co., Ltd.
2026-04-23	1-Bromo-4-iodobenzene 589-87-7	US $0.00 / kg	1kg	99%	1	Nanjing Shunxiang Pharmaceutical Technology Co.,Ltd.
2026-03-20	1-Bromo-4-iodobenzene 589-87-7	US $1.00 / KG	1KG	99%	10 mt	Hebei Chuanghai Biotechnology Co., Ltd

1-Bromo-4-iodobenzene
589-87-7
US $25.00 / KG
98%+
Speranza Chemical Co., Ltd.

1-Bromo-4-iodobenzene
589-87-7
US $0.00 / kg
99%
Nanjing Shunxiang Pharmaceutical Technology Co.,Ltd.

1-Bromo-4-iodobenzene
589-87-7
US $1.00 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

1-Bromo-4-iodobenzene Spectrum

1-Bromo-4-iodobenzene(589-87-7)MS 1-Bromo-4-iodobenzene(589-87-7)¹HNMR 1-Bromo-4-iodobenzene(589-87-7)¹³CNMR 1-Bromo-4-iodobenzene(589-87-7)IR1 1-Bromo-4-iodobenzene(589-87-7)IR2 1-Bromo-4-iodobenzene(589-87-7)IR3 1-Bromo-4-iodobenzene(589-87-7)Raman

589-87-7(1-Bromo-4-iodobenzene)Related Search:

4-Bromomethylbenzoic acid 4-Iodoanisole Iodobenzene 1,4-Diiodobenzene 4-Pentylbromobenzene

4-Bromobenzoic acid 4'-Bromoacetophenone 4-Bromobenzotrifluoride 4-Bromofluorobenzene 4-Isopropylaniline

Methyl 4-bromobenzoate Ethyl 4-bromophenylacetate 4-Bromophenylacetic acid 4-Bromobenzaldehyde (Diacetoxyiodo)benzene

1-BROMO-3-IODOBENZENE,1-Bromo-3-iodobenzene (stabilized with Copper chip),3-BROMO-1-IODOBENZENE,1-Bromo-3-iodobenzene,98% 1-Bromo-2-iodobenzene Bromine

1of4

benzene,1-broMo-4-iodo- 1-BroMo-4-iodobenzene, 98% 25GR 1-Brom-4-iodobenzene 4-Bromoiodobenzene 99+% 4-BroMoiodobenzene, 97+% 4-BroMoiodoben The broMine iodobenzene 4-Bromoiodobenzene p-Bromoiodobenzene 4-Bromo-1-iodobenzene for synthesis 4-Bromophenyl iodide 4-Iodo-1-bromobenzene 4-Iodophenyl bromide 1,4-bromoiodobenzene 4-Bromoiodobenzene 98% Vortioxetine Impurity 53 4-IODOBROMOBENZENE 4-BROMO-1-IODOBENZENE 1-BROMO-4-IODOBENZENE 1-bromo-4-iodo-benzen p-Bromophenyl iodide p-Iodobromobenzene P-BROMOIODOBENZENE 1-bromo-4-oiodobenzene 1-Bromo-4-iodobenzene,98% p-Bromoiodobenzene 1-Bromo-4-Iodo Benzene p-Bromiodobenzene 1-BROMO-IODOBENZENE 1-Bromo-4-Iodobenzene>99% 1-Bromo-4-iodobenzene, 97+% 1-Bromo-4-iodobenzene > 4- Bromiodobenzene 1-Bromo-4-iodobenzene ISO 9001：2015 REACH 4-Bromoiodobenzene CAS 4-Bromiodobenzene (4-Bromiodobenzene) 1-Brom-4-iodbenzol 4-BROMOIODOBENZENE 589-87-7 C6H4BrI ARYL HALIDE Organic Building Blocks Halogenated Hydrocarbons Building Blocks Aryl C6 Building Blocks Chemical Synthesis Halogenated Hydrocarbons Organic Building Blocks alkyl Iodine|alkyl bromide Halogenated benzene series Miscellaneous Benzene derivates Bromine Compounds Iodine Compounds Light yellow crystalline powder Aryl Halogenated Hydrocarbons bc0001