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AP-III-a4

AP-III-a4 Structure
AP-III-a4 structure
CAS No.
1177827-73-4
Chemical Name:
AP-III-a4
Synonyms
CS-1077;ENOBLOCK;AP-III-a4;ENOblock (AP-III-a4);ENOBLOCK HYDROCHLORIDE;AP-III-a4(ENOblock), >98%;Inhibitor,AP-III-a-4,Phosphopyruvate hydratase,Apoptosis,inhibit,antidiabetic,anticancer,HCT116,Enolase,Huh7,zebrafish,APIIIa4,HEK,AP III a4;N-[2-[2-(2-Aminoethoxy)ethoxy]ethyl]-4-[[4-[(cyclohexylmethyl)amino]-6-[[(4-fluorophenyl)methyl]amino]-1,3,5-triazin-2-yl]amino]benzeneacetamide;Benzeneacetamide, N-[2-[2-(2-aminoethoxy)ethoxy]ethyl]-4-[[4-[(cyclohexylmethyl)amino]-6-[[(4-fluorophenyl)methyl]amino]-1,3,5-triazin-2-yl]amino]-;AP-III-A4 Benzeneacetamide, N-[2-[2-(2-aminoethoxy)ethoxy]ethyl]-4-[[4-[(cyclohexylmethyl)amino]-6-[[(4-fluorophenyl)methyl]amino]-1,3,5-triazin-2-yl]amino]-
CBNumber:
CB42685920
Molecular Formula:
C31H43FN8O3
Molecular Weight:
594.72
MDL Number:
MFCD28009373
MOL File:
1177827-73-4.mol
Last updated:2025-10-29 15:43:00
Product description Number Pack Size Price
AP-III-a4 ≥95% 19933 1mg $71
AP-III-a4 ≥95% 19933 5mg $313
AP-III-a4 ≥95% 19933 10mg $590
AP-III-a4 ≥95% 19933 25mg $855
AP-III-a4 B3588 5mg $344
More product size
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AP-III-a4 Properties

Density 1.250±0.06 g/cm3(Predicted)
storage temp. 2-8°C(protect from light)
solubility Soluble in DMSO
form Powder
pka 15.25±0.46(Predicted)
color Off-white to light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P271-P280-P301+P312-P330-P302+P352-P321-P304+P340-P305+P351+P338-P332+P313-P362+P364-P337+P313-P403+P233-P405-P501
NFPA 704
0
2 0

AP-III-a4 price More Price(21)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 19933 AP-III-a4 ≥95% 1177827-73-4 1mg $71 2024-03-01 Buy
Cayman Chemical 19933 AP-III-a4 ≥95% 1177827-73-4 5mg $313 2024-03-01 Buy
Cayman Chemical 19933 AP-III-a4 ≥95% 1177827-73-4 10mg $590 2024-03-01 Buy
Cayman Chemical 19933 AP-III-a4 ≥95% 1177827-73-4 25mg $855 2021-12-16 Buy
ApexBio Technology B3588 AP-III-a4 1177827-73-4 5mg $344 2021-12-16 Buy
Product number Packaging Price Buy
19933 1mg $71 Buy
19933 5mg $313 Buy
19933 10mg $590 Buy
19933 25mg $855 Buy
B3588 5mg $344 Buy

AP-III-a4 Chemical Properties,Uses,Production

Uses

AP-III-a4 (ENOblock) is a nonsubstrate analogue enolase inhibitor with an IC50 of 0.576 uM. AP-III-a4 can be used for the research of cancer and diabetic[1].

in vivo

AP-III-a4 (ENOblock) (10 μM; 96 h) inhibits cancer cell metastasis and suppresses the gluconeogenesis regulator PEPCK in zebrafish[1].

Animal Model:The zebrafish cancer cell HCT116 xenograft model[1]
Dosage:10 μM
Administration:96 h
Result:Reduced cancer cell dissemination. Inhibited PEPCK expression and induced glucose uptake. Inhibited adipogenesis and foam cell formation.

References

[1] Da-Woon Jung, et al. A Unique Small Molecule Inhibitor of Enolase Clarifies Its Role in Fundamental Biological Processes.ACS Chem. Biol., 2013, 8 (6), pp 1271–1282 DOI:10.1021/cb300687k

AP-III-a4 Preparation Products And Raw materials

Raw materials

Preparation Products

AP-III-a4 Suppliers

Global( 82)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29799 58
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32435 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc. 		+1-781-999-5354; support@targetmol.com United States 39035 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		13417589054 trendseenbio@gmail.com China 11681 58
Aladdin Scientific 		tp@aladdinsci.com United States 57505 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131957 58
Shanghai Boyle Chemical Co., Ltd. sales@boylechem.com China 2922 55
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 12952 65
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
TargetMol Chemicals Inc. 		58
InvivoChem 		58
TargetMol Chemicals Inc. 		58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		58
Aladdin Scientific 		58
Amadis Chemical Company Limited 		58
Shanghai Boyle Chemical Co., Ltd. 55
BOC Sciences 65

View Lastest Price from AP-III-a4 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
AP-III-a4 pictures 2025-10-26 AP-III-a4
1177827-73-4
 US $47.00-216.00 / mg 98.24% 10g TargetMol Chemicals Inc.
AP-III-a4 pictures 2020-01-10 AP-III-a4
1177827-73-4
 US $5.50 / g 1g 98%min 10g,100g,1kg Career Henan Chemical Co
  • AP-III-a4 pictures
  • AP-III-a4
    1177827-73-4
  • US $47.00-216.00 / mg
  • 98.24%
  • TargetMol Chemicals Inc.
  • AP-III-a4 pictures
  • AP-III-a4
    1177827-73-4
  • US $5.50 / g
  • 98%min
  • Career Henan Chemical Co

AP-III-a4 Spectrum

AP-III-a4(1177827-73-4)1HNMR
AP-III-a4 ENOblock (AP-III-a4) AP-III-A4 Benzeneacetamide, N-[2-[2-(2-aminoethoxy)ethoxy]ethyl]-4-[[4-[(cyclohexylmethyl)amino]-6-[[(4-fluorophenyl)methyl]amino]-1,3,5-triazin-2-yl]amino]- N-[2-[2-(2-Aminoethoxy)ethoxy]ethyl]-4-[[4-[(cyclohexylmethyl)amino]-6-[[(4-fluorophenyl)methyl]amino]-1,3,5-triazin-2-yl]amino]benzeneacetamide AP-III-a4(ENOblock), >98% ENOBLOCK CS-1077 ENOBLOCK HYDROCHLORIDE Benzeneacetamide, N-[2-[2-(2-aminoethoxy)ethoxy]ethyl]-4-[[4-[(cyclohexylmethyl)amino]-6-[[(4-fluorophenyl)methyl]amino]-1,3,5-triazin-2-yl]amino]- Inhibitor,AP-III-a-4,Phosphopyruvate hydratase,Apoptosis,inhibit,antidiabetic,anticancer,HCT116,Enolase,Huh7,zebrafish,APIIIa4,HEK,AP III a4 1177827-73-4 C31H43FN8O3