ChemicalBook >> CAS DataBase List >>MK-4827 (R-enantioMer)

MK-4827 (R-enantioMer)

CAS No.
1038915-58-0
Chemical Name:
MK-4827 (R-enantioMer)
Synonyms
(R)-Niraparib;ent-Niraparib;ent-Nirapanib;Niraparib Impurity;Niraparib Impurity 13;Niraparib Impurity 51;MK-4827 (R-enantioMer);Niraparib R-enantiomer;R isomer of MK-4827, Niraparib;Niraparib R-enantiomer p-tosylate
CBNumber:
CB42716288
Molecular Formula:
C19H20N4O
Molecular Weight:
320.39
MDL Number:
MOL File:
1038915-58-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 05:20:04
Product description Number Pack Size Price
ent-Niraparib NRB91558 10mg $575.7
ent-Niraparib NRB91558 25mg $1079.5
ent-Niraparib NRB91558 50mg $1727
ent-Niraparib NRB91558 100mg $2764
Niraparib (R-enantiomer) 99.29% CS-3085 5mg $76
More product size

MK-4827 (R-enantioMer) Properties

Boiling point 463.6±45.0 °C(Predicted)
Density 1.34±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : ≥ 32 mg/mL (99.88 mM)
pka 15.36±0.30(Predicted)
form Solid
color Light yellow to yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)Health Hazard (GHS08)
GHS07,GHS08
Signal word  Danger
Hazard statements  H302-H340
Precautionary statements  P260-P264-P270-P280-P281-P330-P301+P312-P405-P501

MK-4827 (R-enantioMer) price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth NRB91558 ent-Niraparib 1038915-58-0 10mg $575.7 2026-06-04 Buy
Biosynth NRB91558 ent-Niraparib 1038915-58-0 25mg $1079.5 2026-06-04 Buy
Biosynth NRB91558 ent-Niraparib 1038915-58-0 50mg $1727 2026-06-04 Buy
Biosynth NRB91558 ent-Niraparib 1038915-58-0 100mg $2764 2026-06-04 Buy
ChemScene CS-3085 Niraparib (R-enantiomer) 99.29% 1038915-58-0 5mg $76 2026-06-04 Buy
Product number Packaging Price Buy
NRB91558 10mg $575.7 Buy
NRB91558 25mg $1079.5 Buy
NRB91558 50mg $1727 Buy
NRB91558 100mg $2764 Buy
CS-3085 5mg $76 Buy

MK-4827 (R-enantioMer) Chemical Properties,Uses,Production

Uses

ent-Niraparib is an isomer of Niraparib (N481400), a novel oral poly(ADP-ribose)polymerase (PARP) inhibitor efficacious in BRCA-1 and -2 mutant tumors.

Definition

ChEBI: 2-{4-[(3R)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide is a 2-[4-(piperidin-3-yl)phenyl]-2H-indazole-7-carboxamide that has R-configuration. It is a potent PARP1 inhibitor with IC50 of 2.4 nM. It has a role as an EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor and an antineoplastic agent.

IC 50

PARP-1: 2.4 nM (IC50)

MK-4827 (R-enantioMer) Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 48)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 33024 60
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32466 58
Career Henan Chemica Co
+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30225 58
BOC Sciences
16314854226; +16314854226 inquiry@bocsci.com United States 19853 58
InvivoChem
+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc.
+1-781-999-5354; support@targetmol.com United States 39039 58
HANGZHOU LEAP CHEM CO., LTD.
+86-571-87711850 market18@leapchem.com China 43333 58
Aladdin Scientific
tp@aladdinsci.com United States 52923 58
ShenZhen H&D Pharmaceutical Technology Co., LTD
+8618627948422 sale@hdimpurity.com China 3681 58
Moxin Chemicals
+86-17320513646 +8617320513646 anna@molcoo.com China 10000 58

View Lastest Price from MK-4827 (R-enantioMer) manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Niraparib (R-enantiomer) pictures 2026-05-11 Niraparib (R-enantiomer)
1038915-58-0
$56.00-118.00 99.83% 10g TargetMol Chemicals Inc.
Niraparib (R-enantiomer) pictures 2026-05-11 Niraparib (R-enantiomer)
1038915-58-0
$56.00-118.00 99.83% 10g TargetMol Chemicals Inc.
 (R)-Niraparib pictures 2026-03-12 (R)-Niraparib
1038915-58-0
10mg 0.98 10g ShenZhen H&D Pharmaceutical Technology Co., LTD
  •  (R)-Niraparib pictures
  • (R)-Niraparib
    1038915-58-0
  • 0.98
  • ShenZhen H&D Pharmaceutical Technology Co., LTD

MK-4827 (R-enantioMer) Spectrum

MK-4827 (R-enantioMer) Niraparib Impurity R isomer of MK-4827, Niraparib (R)-2-(4-(PIPERIDIN-3-YL)PHENYL)-2H-INDAZOLE-7-CARBOXAMIDE Niraparib R-enantiomer 2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide ent-Niraparib 2H-Indazole-7-carboxamide, 2-[4-(3R)-3-piperidinylphenyl]- poly ADP ribose polymerase,Inhibitor,Niraparib (R enantiomer),PARP,Niraparib (Renantiomer),Niraparib (R-enantiomer),inhibit (R)-Niraparib Niraparib Impurity 13 ent-Nirapanib Niraparib Impurity 51 Niraparib R-enantiomer p-tosylate Niraparib (R-enantiomer), 10 mM in DMSO 1038915-58-0