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Methyl 6-broMo-2-Methoxynicotinate

CAS No.
1009735-24-3
Chemical Name:
Methyl 6-broMo-2-Methoxynicotinate
Synonyms
Methyl 6-broMo-2-Methoxynicotinate;6-bromo-2-methoxynicotinic acid methyl ester;methyl 6-bromo-2-methoxy-pyridine-3-carboxylate;3-Pyridinecarboxylic acid, 6-bromo-2-methoxy-, methyl ester
CBNumber:
CB42732963
Molecular Formula:
C8H8BrNO3
Molecular Weight:
246.06
MDL Number:
MOL File:
1009735-24-3.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:43
Product description Number Pack Size Price
Methyl 6-bromo-2-methoxynicotinate 311183 250.00mg $73
Methyl 6-bromo-2-methoxynicotinate 311183 1.00g $145
Methyl 6-bromo-2-methoxynicotinate 311183 5.00g $428
Methyl 6-bromo-2-methoxynicotinate 95+% M48989 100mg $50
Methyl 6-bromo-2-methoxynicotinate 95+% M48989 250mg $70

Methyl 6-broMo-2-Methoxynicotinate Properties

Boiling point 296.5±35.0 °C(Predicted)
Density 1.530±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka -3.08±0.10(Predicted)
Appearance White to light yellow Solid

Methyl 6-broMo-2-Methoxynicotinate price More Price(21)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 311183 Methyl 6-bromo-2-methoxynicotinate 1009735-24-3 250.00mg $73 2026-05-19 Buy
Matrix Scientific 311183 Methyl 6-bromo-2-methoxynicotinate 1009735-24-3 1.00g $145 2026-05-19 Buy
Matrix Scientific 311183 Methyl 6-bromo-2-methoxynicotinate 1009735-24-3 5.00g $428 2026-05-19 Buy
Synthonix M48989 Methyl 6-bromo-2-methoxynicotinate 95+% 1009735-24-3 100mg $50 2026-05-06 Buy
Synthonix M48989 Methyl 6-bromo-2-methoxynicotinate 95+% 1009735-24-3 250mg $70 2026-05-06 Buy
Product number Packaging Price Buy
311183 250.00mg $73 Buy
311183 1.00g $145 Buy
311183 5.00g $428 Buy
M48989 100mg $50 Buy
M48989 250mg $70 Buy

Methyl 6-broMo-2-Methoxynicotinate Chemical Properties,Uses,Production

Synthesis

6-BROMO-2-METHOXYNICOTINIC ACID

1060806-62-3

Iodomethane

74-88-4

Methyl 6-broMo-2-Methoxynicotinate

1009735-24-3

Step 2: Synthesis of methyl 6-bromo-2-methoxynicotinate; To N,N-dimethylformamide (10 mL), potassium carbonate (1.34 g, 9.48 mmol), 6-bromo-2-methoxynicotinic acid (1.10 g, 4.74 mmol), and iodomethane (0.895 g, 6.31 mmol) were added sequentially. The reaction mixture was stirred at room temperature for 16 hours. After completion of the reaction, the reaction mixture was diluted with water and ethyl acetate and the organic and aqueous layers were separated. The aqueous layer was extracted twice with ethyl acetate. All organic layers were combined, washed with saturated brine, dried over anhydrous magnesium sulfate, filtered and concentrated. The concentrate was purified by silica gel column chromatography using 5%-10% ethyl acetate/heptane gradient elution to afford methyl 6-bromo-2-methoxynicotinate as a colorless oil (0.459 g, 40% yield).1H NMR (500 MHz, DMSO-d6) δppm3.81 (3H, s), 3.93 (3H, s), 7.36 (1H, d, J = 7.8 Hz), 8.06 (1H, d, J = 7.8 Hz).

References

[1] Patent: WO2010/116282, 2010, A1. Location in patent: Page/Page column 60
[2] Journal of Medicinal Chemistry, 2014, vol. 57, # 10, p. 4273 - 4288

Methyl 6-broMo-2-Methoxynicotinate Preparation Products And Raw materials

Methyl 6-broMo-2-Methoxynicotinate Suppliers

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Methyl 6-broMo-2-Methoxynicotinate Spectrum

Methyl 6-broMo-2-Methoxynicotinate 3-Pyridinecarboxylic acid, 6-bromo-2-methoxy-, methyl ester 6-bromo-2-methoxynicotinic acid methyl ester methyl 6-bromo-2-methoxy-pyridine-3-carboxylate 1009735-24-3