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1-(1-Boc-4-piperidyl)-3-methylpyrazole-4-boronic Acid Pinacol Ester

1-(1-Boc-4-piperidyl)-3-methylpyrazole-4-boronic Acid Pinacol Ester structure

CAS No.: 1092563-68-2

Chemical Name:: 1-(1-Boc-4-piperidyl)-3-methylpyrazole-4-boronic Acid Pinacol Ester

Synonyms: 1-(1-Boc-4-piperidyl)-3-methylpyrazole-4-boronic Acid Pinacol Ester;tert-Butyl 4-(3-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)piperid;tert-butyl 4-[3-methyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine-1-carboxylate;tert-Butyl 4-(3-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate;tert-butyl 4-[3-methyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine-1-carboxylate - [B16511];tert-butyl 4-(3-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1l4,2l2-pyrazol-1-yl)piperidine-1-carboxylate;1-Piperidinecarboxylic acid, 4-[3-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]-, 1,1-dimethylethyl ester

CBNumber:: CB42738682

Molecular Formula:: C20H34BN3O4

Molecular Weight:: 391.31

MDL Number:: MFCD22570866

MOL File:: 1092563-68-2.mol

MSDS File:: SDS

Last updated:2026-05-28 05:27:39

Request For Quotation

1-(1-Boc-4-piperidyl)-3-methylpyrazole-4-boronic Acid Pinacol Ester Properties

Boiling point	503.3±50.0 °C(Predicted)
Density	1.13±0.1 g/cm3(Predicted)
storage temp.	Inert atmosphere,Store in freezer, under -20°C
pka	3.60±0.19(Predicted)
Appearance	white solid

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H332-H335
Precautionary statements	P261-P280-P305+P351+P338

1-(1-Boc-4-piperidyl)-3-methylpyrazole-4-boronic Acid Pinacol Ester price More Price(24)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Matrix Scientific	161488	tert-Butyl 4-(3-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate	1092563-68-2	1.00g	$1446	2026-05-18	Buy
Synthonix	B16511	tert-butyl 4-[3-methyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine-1-carboxylate 97.0%	1092563-68-2	100mg	$490	2026-05-06	Buy
Synthonix	B16511	tert-butyl 4-[3-methyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine-1-carboxylate 97.0%	1092563-68-2	250mg	$750	2026-05-06	Buy
Synthonix	B16511	tert-butyl 4-[3-methyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine-1-carboxylate 97.0%	1092563-68-2	500mg	$1230	2026-05-06	Buy
Synthonix	B16511	tert-butyl 4-[3-methyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine-1-carboxylate 97.0%	1092563-68-2	1g	$1820	2026-05-06	Buy

Product number	Packaging	Price	Buy
161488	1.00g	$1446	Buy
B16511	100mg	$490	Buy
B16511	250mg	$750	Buy
B16511	500mg	$1230	Buy
B16511	1g	$1820	Buy

1-(1-Boc-4-piperidyl)-3-methylpyrazole-4-boronic Acid Pinacol Ester Chemical Properties, Uses, Production

Synthesis

1-Piperidinecarboxylic acid, 4-(4-bromo-5-methyl-1H-pyrazol-1-yl)-, 1,1-dimethylethyl ester

1076223-99-8

tert-Butyl 4-(4-bromo-5-methylpyrazol-1-yl)piperidine-1-carboxylate

1092500-89-4

73183-34-3

1-(1-Boc-4-piperidyl)-3-methylpyrazole-4-boronic Acid Pinacol Ester

1092563-68-2

Tert-butyl 4-(4-bromo-3-methyl-1H-pyrazol-1-yl)piperidine-1-carboxylate (2.7 g), pinacol ester of biphenylboronic acid (4.98 g), 1,1'-bis(diphenylphosphino)ferrocene palladium(II) dichloride-CH2Cl2 adduct (0.634 g), and potassium acetate (2.31 g) were used as raw materials, in DMSO (40 ml) at 80 °C under The reaction was stirred for 4 hours. After completion of the reaction, the reaction mixture was cooled to room temperature, quenched with water (25 ml) and extracted with ethyl acetate (3 x 40 ml). The organic phases were combined, washed sequentially with water (3 x 30 ml) and brine (1 x 20 ml), dried with magnesium sulfate and concentrated. The residue was purified by rapid chromatography on silica gel, using a petroleum ether solution of 10% to 30% ethyl acetate as eluent, to afford the target product tert-butyl 4-(3-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate (0.937 g, 30.5% yield) as a white solid.NMR data (DMSO-d6): δ 1.24 (s, 12H), 1.41 (s, 9H), 1.71 (dd, 1H), 1.76 (dd, 1H), 1.89-1.96 (m, 2H), 2.22 (s, 3H), 2.85 (bs, 2H), 3.95-4.07 (m, 2H), 4.20-4.29 (m, 1H) , 7.82 (s, 1H).

References

[1] Patent: WO2009/24825, 2009, A1. Location in patent: Page/Page column 162

1-(1-Boc-4-piperidyl)-3-methylpyrazole-4-boronic Acid Pinacol Ester Preparation Products And Raw materials

Raw materials

1-Piperidinecarboxylic acid, 4-(4-bromo-5-methyl-1H-pyrazol-1-yl)-, 1,1-dimethylethyl ester tert-Butyl 4-(4-bromo-5-methylpyrazol-1-yl)piperidine-1-carboxylate Bis(pinacolato)diboron Potassium Acetate Dimethyl sulfoxide

Preparation Products

1-(1-Boc-4-piperidyl)-3-methylpyrazole-4-boronic Acid Pinacol Ester Suppliers

Global Suppliers ( 23)

Supplier	Tel	Email	Country	ProdList	Advantage
ShangHai AmK Pharmaceutical Technology Co., Ltd.	微信 18019252918 18019252918	sale@amkchem.com	China	14982	55
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131885	58
Aikon International Limited	025-58859352 19370895928	sales01@aikonchem.com	China	15078	58
Shanghai Vigor Biotechnology Co., Ltd.	021-18017654 18017654809	sales@vigorchem.cn	China	958	58
Accela ChemBio Inc.	+1-858-6993322 +86-18019713315	info@accelachem.com	United States	21189	58
Shanghai Kaiwei Chemical Technology Co., Ltd.	021-58461859 15821823057	service@aiviche.com	China	49299	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21135	58
Nanjing Shizhou Biology Technology Co.,Ltd	025-85560043 13675144456	sean.lv@synzest.com	China	11432	58
Energy Chemical	400-0056266	marketing1@energy-chemical.com	China	44927	58
Shanghai Sunway Pharmaceutical Technology Co.,Ltd.	13611835272 13611835272	mmwang@sunwaypharm.com	China	44090	58

Supplier	Advantage
ShangHai AmK Pharmaceutical Technology Co., Ltd.	55
Amadis Chemical Company Limited	58
Aikon International Limited	58
Shanghai Vigor Biotechnology Co., Ltd.	58
Accela ChemBio Inc.	58
Shanghai Kaiwei Chemical Technology Co., Ltd.	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
Nanjing Shizhou Biology Technology Co.,Ltd	58
Energy Chemical	58
Shanghai Sunway Pharmaceutical Technology Co.,Ltd.	58

1092563-68-2 (1-(1-Boc-4-piperidyl)-3-methylpyrazole-4-boronic Acid Pinacol Ester) Related Search:

tert-Butyl 4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine-1-carboxylate 1-(4-4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)piperi 1-methyl-4-[4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine (1-(1-(tert-Butoxycarbonyl)piperidin-4-yl)-3-methyl-1H-pyrazol-4-yl)boronic acid Piperidine, 4-[3-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]-

1-Piperidinecarboxylic acid, 4-[3,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]-, 1,1-dimethylethyl ester

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1-(1-Boc-4-piperidyl)-3-methylpyrazole-4-boronic Acid Pinacol Ester tert-Butyl 4-(3-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate tert-Butyl 4-(3-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)piperid tert-butyl 4-[3-methyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine-1-carboxylate 1-Piperidinecarboxylic acid, 4-[3-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]-, 1,1-dimethylethyl ester tert-butyl 4-(3-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1l4,2l2-pyrazol-1-yl)piperidine-1-carboxylate tert-butyl 4-[3-methyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine-1-carboxylate - [B16511] 1092563-68-2