Ethyl 1-benzylpiperidine-4-carboxylate
- CAS No.
- 24228-40-8
- Chemical Name:
- Ethyl 1-benzylpiperidine-4-carboxylate
- Synonyms
- AKOS 225-01;BUTTPARK 33\04-91;RSYY（Avanafil)-28;RARECHEM AH CK 0037;SDCCGMLS-0066147.P001;Ethyl 1-Benzylisonipecotate;Ethyl N-benzylisonipecotate;1-benzyl-ethyl Isonipecotate;Ethyl N-benzylisonipecotinate;1-Benzyl-4-piperidinecarboxyli
- CBNumber:
- CB4276544
- Molecular Formula:
- C15H21NO2
- Molecular Weight:
- 247.33
- MDL Number:
- MFCD00040748
- MOL File:
- 24228-40-8.mol
| Product description | Number | Pack Size | Price |
| Ethyl 1-Benzyl-4-piperidinecarboxylate >95.0%(GC)(T) | E0862 | 5g | $57 |
| Ethyl 1-Benzyl-4-piperidinecarboxylate >95.0%(GC)(T) | E0862 | 25g | $203 |
| N-Benzyl-4-carboethoxypiperidine | B233660 | 10g | $90 |
| N-Benzyl-4-carboethoxypiperidine | B233660 | 5g | $50 |
| ethyl1-benzylpiperidine-4-carboxylate | CS-M0322 | 1000g | $496 |
| More product size | |||
| Boiling point | 122°C (0.5 mmHg) |
|---|---|
| Density | 1.037 g/mL at 25 °C |
| refractive index | 1.5120-1.5160 |
| Flash point | >110℃ |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Chloroform (Slightly), Hexanes (Slightly), Methanol (Slightly) |
| form | clear liquid |
| pka | 7.93±0.10(Predicted) |
| color | Colorless to Light red |
| InChI | InChI=1S/C15H21NO2/c1-2-18-15(17)14-8-10-16(11-9-14)12-13-6-4-3-5-7-13/h3-7,14H,2,8-12H2,1H3 |
| InChIKey | ASQCOPJFYLJCGD-UHFFFAOYSA-N |
| SMILES | N1(CC2=CC=CC=C2)CCC(C(OCC)=O)CC1 |
| CAS DataBase Reference | 24228-40-8(CAS DataBase Reference) |
| FDA UNII | KCJ9YTK89G |
Ethyl 1-benzylpiperidine-4-carboxylate price More Price(38)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | E0862 | Ethyl 1-Benzyl-4-piperidinecarboxylate >95.0%(GC)(T) | 24228-40-8 | 5g | $57 | 2023-06-20 | Buy |
| TCI Chemical | E0862 | Ethyl 1-Benzyl-4-piperidinecarboxylate >95.0%(GC)(T) | 24228-40-8 | 25g | $203 | 2021-12-16 | Buy |
| TRC | B233660 | N-Benzyl-4-carboethoxypiperidine | 24228-40-8 | 10g | $90 | 2021-12-16 | Buy |
| TRC | B233660 | N-Benzyl-4-carboethoxypiperidine | 24228-40-8 | 5g | $50 | 2021-12-16 | Buy |
| ChemScene | CS-M0322 | ethyl1-benzylpiperidine-4-carboxylate | 24228-40-8 | 1000g | $496 | 2021-12-16 | Buy |
Ethyl 1-benzylpiperidine-4-carboxylate Chemical Properties,Uses,Production
Synthesis
Ethyl isonipecotate (50 g, 0.31 mol) was dissolved in toluene (150 mL) in a round
bottom flask, charged with potassium carbonate (60 g, 0.43
mol) and stirred for 15 min. Benzyl chloride (42 g, 0.31 mol)
was charged and the reaction mass was refluxed for 4 h at
100 °C. Upon completion of the reaction as marked by TLC
(hexane:ethyl acetate; 2:1), the reaction mass was cooled to
room temperature and quenched with water (100 mL), stirred
and the organic phase was separated. The aqueous phase was
again extracted with toluene (100 mL). Combined organic
phase was washed twice with saturated brine solution (50 mL).
Remove toluene in vacuo to obtain Ethyl N-benzylpiperidine-4-carboxylate
( 6.97 g, 91 %) as a yellow liquid.
Chemical Properties
Colourless Oil
References
[1] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 22, p. 6938 - 6942,5
[2] Journal of medicinal chemistry, 1980, vol. 23, # 8, p. 848 - 851
[3] Patent: WO2010/12611, 2010, A1. Location in patent: Page/Page column 28
[4] Journal of Medicinal Chemistry, 1996, vol. 39, # 3, p. 749 - 756
[5] Organic Preparations and Procedures International, 1994, vol. 26, # 3, p. 421 - 428
Ethyl 1-benzylpiperidine-4-carboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 880 | 50 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21618 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Zjartschem | +86-571 87238903 | jocelynpan@zjarts.com | CHINA | 988 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29850 | 58 |
| Anhui Dexinjia Biopharm Co., Ltd | +86-531-82375818 +86-15064153060 | sales01@jndxj.com | China | 301 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Changzhou Ditong Chemical Co.,Ltd | +86-0519-88299272 | info@edengenechem.com | China | 2176 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
View Lastest Price from Ethyl 1-benzylpiperidine-4-carboxylate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-04 | Ethyl 1-benzylpiperidine-4-carboxylate
24228-40-8
|
US $0.00-0.00 / KG | 1KG | 98% | 1ton | Henan Aochuang Chemical Co.,Ltd. | |
 |
2024-04-02 | Ethyl 1-benzylpiperidine-4-carboxylate
24228-40-8
|
US $10.00-100.00 / kg | 1kg | 99% | 5000 Metric Ton/Month | Wuhan Xinhao Biotechnology Co., Ltd | |
 |
2023-09-11 | Ethyl N-benzyl piperidine-4-carboxylate
24228-40-8
|
US $100.00 / bag | 1bag | 99 | 5000 | Hebei Fengqiang Trading Co., LTD |
-
- Ethyl 1-benzylpiperidine-4-carboxylate
24228-40-8
- US $0.00-0.00 / KG
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- Ethyl 1-benzylpiperidine-4-carboxylate
24228-40-8
- US $10.00-100.00 / kg
- 99%
- Wuhan Xinhao Biotechnology Co., Ltd
-
- Ethyl N-benzyl piperidine-4-carboxylate
24228-40-8
- US $100.00 / bag
- 99
- Hebei Fengqiang Trading Co., LTD
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