4-Chloro-5,6-dimethoxypyrimidine
- CAS No.
- 5193-88-4
- Chemical Name:
- 4-Chloro-5,6-dimethoxypyrimidine
- Synonyms
- Pyrimidine, 4-chloro-5,6-dimethoxy-
- CBNumber:
- CB43039595
- Molecular Formula:
- C6H7ClN2O2
- Molecular Weight:
- 174.59
- MDL Number:
- MFCD24153943
- MOL File:
- 5193-88-4.mol
| Product description | Number | Pack Size | Price |
| 4-Chloro-5,6-dimethoxypyrimidine | 2692DA | 5g | $802 |
| 4-Chloro-5,6-dimethoxypyrimidine 97% | A136138 | 100mg | $29 |
| 4-Chloro-5,6-dimethoxypyrimidine 97% | A136138 | 250mg | $43 |
| 4-Chloro-5,6-dimethoxypyrimidine 97% | A136138 | 1g | $108 |
| 4-Chloro-5,6-dimethoxypyrimidine 97% | CM253367 | 1g | $153 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H320-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
4-Chloro-5,6-dimethoxypyrimidine price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| AK Scientific | 2692DA | 4-Chloro-5,6-dimethoxypyrimidine | 5193-88-4 | 5g | $802 | 2021-12-16 | Buy |
| Ambeed | A136138 | 4-Chloro-5,6-dimethoxypyrimidine 97% | 5193-88-4 | 100mg | $29 | 2021-12-16 | Buy |
| Ambeed | A136138 | 4-Chloro-5,6-dimethoxypyrimidine 97% | 5193-88-4 | 250mg | $43 | 2021-12-16 | Buy |
| Ambeed | A136138 | 4-Chloro-5,6-dimethoxypyrimidine 97% | 5193-88-4 | 1g | $108 | 2021-12-16 | Buy |
| Chemenu | CM253367 | 4-Chloro-5,6-dimethoxypyrimidine 97% | 5193-88-4 | 1g | $153 | 2021-12-16 | Buy |
4-Chloro-5,6-dimethoxypyrimidine Chemical Properties,Uses,Production
Synthesis
124-41-4
5018-38-2
5193-88-4
Preparation of compound 4-chloro-5,6-dimethoxypyrimidine: 4,6-dichloro-5-methoxypyrimidine (300 mg, 1.68 mmol) was dissolved in methanol (10 mL), followed by cooling of the reaction mixture to 0 °C. Under stirring, sodium methanolate (99 mg, 1.85 mmol) was slowly added, and after addition, the reaction mixture was allowed to gradually warm up to room temperature. The reaction mixture was stirred continuously for 19 hours at room temperature. After completion of the reaction, methanol was removed by distillation under reduced pressure. The resulting residue was diluted with ethyl acetate and washed sequentially with saturated aqueous sodium bicarbonate solution, aqueous ammonium chloride solution and brine. The organic layer was dried over anhydrous sodium sulfate and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography with 0 to 10% ethyl acetate/hexane as eluent to give 4-chloro-5,6-dimethoxypyrimidine as a white solid (168 mg, 57% yield). Physical Properties: Melting point 53-55°C. NMR data: 1H NMR (400 MHz, CDCl3) δ 8.27 (s, 1H), 4.03 (s, 3H), 3.88 (s, 3H); 13C NMR (100 MHz, CDCl3) δ 163.6, 151.6, 151.3, 138.2, 60.7, 54.8.
References
[1] Patent: WO2014/43252, 2014, A2. Location in patent: Page/Page column 62
4-Chloro-5,6-dimethoxypyrimidine Preparation Products And Raw materials
Raw materials
Preparation Products
4-Chloro-5,6-dimethoxypyrimidine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30227 | 58 |
| KARMEL TECHNOLOGY (HK) CO.,LIMITED | +8618795957998 | karmelhk@126.com | CHINA | 2886 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39927 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| BeiJing Hwrk Chemicals Limted | 0757-86329057 18934348241 | sales4.gd@hwrkchemical.com | China | 14063 | 55 |
| Hunan HuaTeng Pharmaceutical Co., Ltd., | 400-8592883 | sales@huatengsci.com | China | 5873 | 58 |
| Shanghai Xingui Biotechnology Co., Ltd. | 15121041756 | xingui2022@126.com | China | 9984 | 58 |
| Yancheng KangdiSen Pharmaceutical Co., Ltd. | 13812573443 | tongbenwan22@163.com | China | 1977 | 55 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 86249 | 60 |
