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ChemicalBook >> CAS DataBase List >>2,2-Dimethyl-1,3-dioxolane-4-methanol

2,2-Dimethyl-1,3-dioxolane-4-methanol

2,2-Dimethyl-1,3-dioxolane-4-methanol Structure
2,2-Dimethyl-1,3-dioxolane-4-methanol structure
CAS No.
100-79-8
Chemical Name:
2,2-Dimethyl-1,3-dioxolane-4-methanol
Synonyms
Glycerol acetonide;ISOPROPYLIDENEGLYCEROL;2,2-DIMETHYL-1,3-DIOXOLANE-4-METHANOL;isopropylidene;glycerolacetonide;AUGEO;1,2-ISOPROPYLIDENEGLYCEROL;GIE;ideneg;idenegL
CBNumber:
CB4305646
Molecular Formula:
C6H12O3
Molecular Weight:
132.16
MDL Number:
MFCD00063238
MOL File:
100-79-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:58:44
Product description Number Pack Size Price
DL-1,2-Isopropylideneglycerol ≥97.0% 122696 100g $45.6
DL-1,2-Isopropylideneglycerol ≥97.0% 122696 3kg $378
2,2-Dimethyl-1,3-dioxolane-4-methanol >98.0%(GC) D0710 25g $43
2,2-Dimethyl-1,3-dioxolane-4-methanol >98.0%(GC) D0710 100g $95
DL-1,2-Isopropylideneglycerol ≥97.0% 122696 500g $93.4
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2,2-Dimethyl-1,3-dioxolane-4-methanol Properties

Melting point -27℃
Boiling point 189-191 °C
Density 1.066 g/mL at 20 °C(lit.)
vapor pressure 34Pa at 20℃
refractive index n20/D 1.434
Flash point 176 °F
storage temp. Sealed in dry,2-8°C
solubility 172g/l soluble
pka 14.20±0.10(Predicted)
form Liquid
color Clear colorless
PH 4.0-7.5 (H2O)
optical activity 4.1°(C=1.00 g/100mL, ETOH, 20°C, 589nm)
Water Solubility miscible
Merck 14,5213
BRN 104465
Cosmetics Ingredients Functions HAIR CONDITIONING
InChI 1S/C6H12O3/c1-6(2)8-4-5(3-7)9-6/h5,7H,3-4H2,1-2H3
InChIKey RNVYQYLELCKWAN-UHFFFAOYSA-N
SMILES CC1(C)OCC(CO)O1
LogP 0.3 at 20℃
CAS DataBase Reference 100-79-8(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 3XK098O8ZW
NIST Chemistry Reference 1,3-Dioxolane-4-methanol, 2,2-dimethyl-(100-79-8)
EPA Substance Registry System 1,3-Dioxolane-4-methanol, 2,2-dimethyl- (100-79-8)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H319
Precautionary statements  P264-P280-P305+P351+P338-P337+P313
PPE Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  23-24/25-36-26
WGK Germany  2
RTECS  JI0400000
F  10
TSCA  TSCA listed
HS Code  29329970
Storage Class 10 - Combustible liquids
Hazard Classifications Eye Irrit. 2
Repr. 2
Toxicity LD50 in rats (g/kg): 7 orally; 3 i.p. (Perez)
NFPA 704
2
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2,2-Dimethyl-1,3-dioxolane-4-methanol price More Price(39)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 122696 DL-1,2-Isopropylideneglycerol ≥97.0% 100-79-8 100g $45.6 2026-03-19 Buy
Sigma-Aldrich 122696 DL-1,2-Isopropylideneglycerol ≥97.0% 100-79-8 3kg $378 2026-03-19 Buy
TCI Chemical D0710 2,2-Dimethyl-1,3-dioxolane-4-methanol >98.0%(GC) 100-79-8 25g $43 2026-03-19 Buy
TCI Chemical D0710 2,2-Dimethyl-1,3-dioxolane-4-methanol >98.0%(GC) 100-79-8 100g $95 2026-03-19 Buy
Sigma-Aldrich 122696 DL-1,2-Isopropylideneglycerol ≥97.0% 100-79-8 500g $93.4 2026-03-19 Buy
Product number Packaging Price Buy
122696 100g $45.6 Buy
122696 3kg $378 Buy
D0710 25g $43 Buy
D0710 100g $95 Buy
122696 500g $93.4 Buy

2,2-Dimethyl-1,3-dioxolane-4-methanol Chemical Properties,Uses,Production

Chemical Properties

clear colourless liquid

Uses

A MEK inhibitor

Uses

Solketal is useful for synthesis of mono-, di- and triglycerides. It is used as the starting reagent for synthesis of tulipaline derivatives. It acts as a fuel additive in gasoline. It is an inhibitor of Methyl ethyl ketone .

Uses

DL-1,2-Isopropylideneglycerol was used as the starting reagent for synthesis of tulipaline derivatives.

Synthesis Reference(s)

Tetrahedron, 52, p. 9387, 1996 DOI: 10.1016/0040-4020(96)00501-7
The Journal of Organic Chemistry, 53, p. 2859, 1988 DOI: 10.1021/jo00247a043

General Description

DL-1,2-Isopropylideneglycerol undergoes effective isopropylidenation and deprotection reaction catalyzed by phosphotungstic acid.

Safety Profile

A poison by intravenous route. An eye irritant. Mutation data reported. A very dangerous fire hazard when exposed to heat or flame; can react vigorously with oxidizing materials. To fight fire, use alcohol foam, CO2, dry chemical. When heated to decomposition it emits acrid smoke and fumes.

2,2-Dimethyl-1,3-dioxolane-4-methanol Preparation Products And Raw materials

Raw materials

Glycerol HYDROGEN CYANIDE

Preparation Products

2,3-DIHYDROXYPROPYL METHACRYLATE BENZYL GLYCIDYL ETHER 3-ETHOXY-1,2-PROPANEDIOL 2,2-DIMETHYL-1,3-DIOXOLAN-4-YLMETHYL P-TOLUENESULFONATE Dropropizine
1,3-Dioxan-5-ol, 2,2-dimethyl- 4-[(2,3-EPOXYPROPOXY)METHYL]-2,2-DIMETHYL-1,3-DIOXOLANE (R)-4-BENZYLOXYMETHYL-2,2-DIMETHYL-1,3-DIOXOLANE SELACHYL ALCOHOL (2,2-DIMETHYL-[1,3]-DIOXOLAN-4-YL)-METHYLAMINE
3-BROMO-1,2-PROPANEDIOL 4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE 1,3-Dioxolane-4-carboxylicacid,2,2-dimethyl-,methylester(9CI)

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2,2-Dimethyl-1,3-dioxolane-4-methanol Suppliers

Global( 450)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Chuanghai Biotechnology Co., Ltd 		+8615350571055 Sibel@chuanghaibio.com China 8738 58
Wuhan Fortuna Chemical Co., Ltd 		+86-27-59207850 info@fortunachem.com China 5975 58
Hebei Chuanghai Biotechnology Co,.LTD 		+86-86-13131129325 +8613131129325 sales1@chuanghaibio.com China 5235 58
Hebei Chuanghai Biotechnology Co., Ltd 		+8615531151365 mina@chuanghaibio.com China 18126 58
Hebei Jingbo New Material Technology Co., Ltd 		+8619931165850 hbjbtech@163.com China 1000 58
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 20124 58
Hebei Zhuanglai Chemical Trading Co.,Ltd 		+8613343047651 admin@zlchemi.com China 3692 58
Hebei Longbang Technology Co., LTD 		+86-18633929156 admin@hblongbang.com China 972 58
Shandong Deshang Chemical Co., Ltd. 		+86-0531-8875-2665 +8613153039501 info@deshangchem.com China 661 58
HebeiShuoshengImportandExportco.,Ltd 		+86-18532138899 L18532138899@163.com China 939 58
Supplier Advantage
Hebei Chuanghai Biotechnology Co., Ltd 		58
Wuhan Fortuna Chemical Co., Ltd 		58
Hebei Chuanghai Biotechnology Co,.LTD 		58
Hebei Chuanghai Biotechnology Co., Ltd 		58
Hebei Jingbo New Material Technology Co., Ltd 		58
Henan Fengda Chemical Co., Ltd 		58
Hebei Zhuanglai Chemical Trading Co.,Ltd 		58
Hebei Longbang Technology Co., LTD 		58
Shandong Deshang Chemical Co., Ltd. 		58
HebeiShuoshengImportandExportco.,Ltd 		58

View Lastest Price from 2,2-Dimethyl-1,3-dioxolane-4-methanol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,2-Dimethyl-1,3-dioxolane-4-methanol pictures 2026-04-24 2,2-Dimethyl-1,3-dioxolane-4-methanol
100-79-8
 US $0.00-0.00 / KG 1KG 99.84% 1000kg WUHAN FORTUNA CHEMICAL CO., LTD
Solketal pictures 2026-04-24 Solketal
100-79-8
 0.99 RongNa Biotechnology Co.,Ltd
Solketal pictures 2026-03-20 Solketal
100-79-8
 US $1.00 / KG 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
  • Solketal pictures
  • Solketal
    100-79-8
  • 0.99
  • RongNa Biotechnology Co.,Ltd
  • Solketal pictures
  • Solketal
    100-79-8
  • US $1.00 / KG
  • 99%
  • Hebei Chuanghai Biotechnology Co., Ltd

2,2-Dimethyl-1,3-dioxolane-4-methanol Spectrum

Solketal(100-79-8)MSSolketal(100-79-8)1HNMRSolketal(100-79-8)IR1Solketal(100-79-8)IR2Solketal(100-79-8)Raman

100-79-8(2,2-Dimethyl-1,3-dioxolane-4-methanol)Related Search:

Dimethyl carbonate Dimethyl disulfide Lithium diisopropylamide Dimethyl fumarate N,N-Diisopropylethylamine
Methanol 3-Methyl-2-butanone 1,3-Dioxan-5-ol Dimethyl ether Tris(hydroxymethyl)nitromethane
Chloromethyl isopropyl carbonate Isopropylhydrazine Hydrochloride Allyl glycidyl ether Dacthal ETHANE
Triisopropylsilane Dimethyl sulfoxide Glycerol

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DL-ALPHA,BETA-ISOPROPYLIDENEGLYCEROL LABOTEST-BB LT00233172 ISOPROPYLIDENGLYCEROL ISOPROPYLIDENEGLYCEROL GLYCEROL DIMETHYLKETAL 2,3-O-ISOPROPYLIDENEGLYCEROL (+/-)-2,2-DIMETHYL-1,3-DIOXOLANE-4-METHANOL 2,2-DIMETHYL-1,3-DIOXOLANE-4-METHANOL (+/-)-2,2-DIMETHYL-4-HYDROXYMETHYL-1,3-DIOXOLANE 2,2-DIMETHYL-4-HYDROXYMETHYL-1,3-DIOXOLANE 1,2-O-ISOPROPYLIDENEGLYCEROL 1,2-ISOPROPYLIDENEGLYCEROL 1,2-ISOPROPYLIDENE-RAC-GLYCEROL 1,2-Isopropylideneglycerin 1,2-O,O-Isopropylideneglycerin (+/-)-2,2-Dimethyl-1,3-dioxolane-4-methanol~(+/-)-1,2-O-Isopropylideneglycerol 4-hydroxymethyl-2,2-dimethyl-1,3-dioxolan glycerol 1,2-isopropylidene ether DL-1,2-Isopropylideneglycerol, 98% 2,2-DIMETHYL-1,3-DIOXOLANE-4-METHANOL(SOLKETAL) Glycerol α,β-isopropylidene ether Dimethyl-4-hydroxymethyl-1,3-dioxolane 1,3-Dioxolane-4-methanol, 2,2-dimethyl- (n)-1,2-o-isopropylideneglycerol (n)-2,2-dimethyl-1,3-dioxolane-4-methanol ACETONE GLYCERINE KETAL ACETONE KETAL OF GLYCERINE SOLKETAL SOLKETAL(R) (R,S)-ISOPROPYLIDENE GLYCEROL 2,2-Dimethyl-1,3-dioxolan-4-yl methanol glycerol,1,2-o-isopropylidene Glycerolacetone glycerolacetonide isopropylidene dl-α,β-isopropylideneglycerol DL-1,2-Isopropylideneglycerol 98% 1,2-O-Isopropylideneglycerol for synthesis Augeo SL191 THCB 200 AUGEO 2,2-dimethyl-3-dioxolane-4-methanol 2,2-Dimethyl-4-(hydroxymethyl)-1,3-dioxacyclopentane 2,2-Dimethyl-4-hydroxymethyldioxolane 2,2-Dimethyl-4-oxymethyl-1,3-dioxolane 2,2-Dimethyl-5-hydroxymethyl-1,3-dioxolane 1,2-isopropylidine glycerol 2,3-(Isopropylidenedioxy)propanol 2,3-Isopropylideneglycerol 4-(Hydroxymethyl)-2,2-dimethyl-1,3-dioxolane 4-Hydroxymethyl-2,2-dimethyl-1,3-dioxolane Acetone monoglycerol ketal Acetone, cyclic (hydroxymethyl)ethylene acetal acetone,cyclic(hydroxymethyl)ethyleneacetal acetoneglycerol alpha,beta-Isopropylideneglycerol GIE Glycerinisopropylidene ether