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Ethyl 4-(benzyloxy)-3-hydroxybenzoate

CAS No.
177429-27-5
Chemical Name:
Ethyl 4-(benzyloxy)-3-hydroxybenzoate
Synonyms
Ethyl 4-(benzyloxy)-3-hydroxybenzoate;Ethyl 3-hydroxy-4-(phenylmethoxy)benzoate;Benzoic acid, 3-hydroxy-4-(phenylmethoxy)-, ethyl ester
CBNumber:
CB43066124
Molecular Formula:
C16H16O4
Molecular Weight:
272.3
MDL Number:
MOL File:
177429-27-5.mol
MSDS File:
SDS
Last updated:2026-05-28 02:50:44

Ethyl 4-(benzyloxy)-3-hydroxybenzoate Properties

storage temp. 2-8°C
Appearance White to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

Ethyl 4-(benzyloxy)-3-hydroxybenzoate price More Price(19)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 292085 Ethyl 4-(benzyloxy)-3-hydroxybenzoate 177429-27-5 100.00mg $36 2026-05-19 Buy
Matrix Scientific 292085 Ethyl 4-(benzyloxy)-3-hydroxybenzoate 177429-27-5 250.00mg $42 2026-05-19 Buy
Matrix Scientific 292085 Ethyl 4-(benzyloxy)-3-hydroxybenzoate 177429-27-5 1.00g $120 2026-05-19 Buy
aablocks AA00258A Ethyl 4-(benzyloxy)-3-hydroxybenzoate 97% 177429-27-5 100mg $16 2026-05-28 Buy
aablocks AA00258A Ethyl 4-(benzyloxy)-3-hydroxybenzoate 97% 177429-27-5 250mg $20 2026-05-28 Buy
Product number Packaging Price Buy
292085 100.00mg $36 Buy
292085 250.00mg $42 Buy
292085 1.00g $120 Buy
AA00258A 100mg $16 Buy
AA00258A 250mg $20 Buy

Ethyl 4-(benzyloxy)-3-hydroxybenzoate Chemical Properties, Uses, Production

Synthesis

Ethyl 3,4-dihydroxybenzoate

3943-89-3

Benzyl chloride

100-44-7

Ethyl 4-(benzyloxy)-3-hydroxybenzoate

177429-27-5

Step 9a: Synthesis of ethyl 4-(benzyloxy)-3-hydroxybenzoate (compound 502) A mixture of ethyl 3,4-dihydroxybenzoate (9.1 g, 50 mmol), benzyl chloride (6.3 g, 50 mmol), potassium iodide (1.66 g, 10 mmol) and potassium carbonate (13.8 g, 100 mmol) in acetonitrile (250 mL) was reacted by stirring at 40 °C overnight. Upon completion of the reaction, the mixture was cooled to room temperature and filtered. The filtrate was concentrated under reduced pressure and the residue was purified by silica gel column chromatography with petroleum ether/ethyl acetate (10:1, v/v) as eluent to give the title compound 502 as a white solid (4.4 g, 33% yield). LCMS (m/z): 273 [M+1]+. 1H NMR (DMSO-d6): δ 9.49 (s, 1H), 7.35 (m, 7H), 7.08 (d, J = 7.8 Hz, 1H), 5.16 (s, 2H), 4.21 (m, 2H), 1.26 (t, J = 7.5 Hz, 3H).

References

[1] Patent: US2009/76044, 2009, A1. Location in patent: Page/Page column 30

1195945-43-7
177429-27-5
Synthesis of Ethyl 4-(benzyloxy)-3-hydroxybenzoate from Benzoic acid, 3-(acetyloxy)-4-(phenylmethoxy)-, ethyl ester

Ethyl 4-(benzyloxy)-3-hydroxybenzoate Preparation Products And Raw materials

Ethyl 4-(benzyloxy)-3-hydroxybenzoate Suppliers

Global Suppliers ( 14)
Supplier Tel Email Country ProdList Advantage
Shanghai Raise Chemical Technology Co.,Ltd 15026594951 rs@raise-chem.com China 4904 55
Mashilabs (Shanghai) Co.,Ltd. 19916721580 mafarm@126.com China 4534 58
BePharm Ltd 400-685-9117 market@bepharm.com China 15081 60
Energy Chemical 400-0056266 marketing1@energy-chemical.com China 44927 58
Bide Pharmatech Ltd. 400-6005915 sales@picasso-e.com China 39662 58
Suzhou Meishi Biotechnology Co., Ltd. 1173954148q meishipharma@126.com China 20027 58
Shanghai Haohong Scientific Co., Ltd. 400-8210725 4008210725 malulu@leyan.com China 39319 58
Beijing Solarbio Science & Tecnology Co., Ltd. 010-50973130 17801761073 Gsiyu@solarbio.com China 50460 58
Zhuhai Aobokai Biomedical Technology Co., Ltd. 400-0628126 sales-team@aobchem.com.cn China 49939 58
Pharmalego 18321033991 marketing@pharmalego.com China 4109 58

Ethyl 4-(benzyloxy)-3-hydroxybenzoate Spectrum

Ethyl 4-(benzyloxy)-3-hydroxybenzoate Benzoic acid, 3-hydroxy-4-(phenylmethoxy)-, ethyl ester Ethyl 3-hydroxy-4-(phenylmethoxy)benzoate 177429-27-5