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ChemicalBook >> CAS DataBase List >>2-cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carboxylate

2-cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carboxylate

2-cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carboxylate Structure
2-cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carboxylate structure
CAS No.
1050477-43-4
Chemical Name:
2-cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carboxylate
Synonyms
Finelidone Impurity 52;Fenelunitinib intermediate;2-cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-terahydro－1,6－naphthyridine-3-carboxylate;2-cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-l,6-naphthyridine-3-carboxylate;2-cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carboxylate;2-Cyanoethyl 4-(4-cyano-2-methoxyphenyl)-1,4,5,6-tetrahydro-2,8-dimethyl-5-oxo-1,6-naphthyridine-3-carboxylate;1,6-Naphthyridine-3-carboxylic acid, 4-(4-cyano-2-methoxyphenyl)-1,4,5,6-tetrahydro-2,8-dimethyl-5-oxo-, 2-cyanoethyl ester;1,6-Naphthyridine-3-carboxylic acid, 4-(4-cyano-2-methoxyphenyl)-1,4,5,6-tetrahydro-2,8-dimethyl-5-oxo-, 2-cyanoethyl ester (ACI);2-cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carboxylate (Finerenone)
CBNumber:
CB43165232
Molecular Formula:
C22H20N4O4
Molecular Weight:
404.42
MDL Number:
MOL File:
1050477-43-4.mol
MSDS File:
SDS
Last updated:2026-05-12 09:16:02
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2-cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carboxylate Properties

vapor pressure 0.006Pa at 25℃
Water Solubility 6.2mg/L at 20℃
InChI InChI=1S/C22H20N4O4/c1-12-11-25-21(27)19-18(15-6-5-14(10-24)9-16(15)29-3)17(13(2)26-20(12)19)22(28)30-8-4-7-23/h5-6,9,11,18,26H,4,8H2,1-3H3,(H,25,27)
InChIKey YUBVPYQJGHKIIA-UHFFFAOYSA-N
SMILES N1C2=C(C(=O)NC=C2C)C(C2=CC=C(C#N)C=C2OC)C(C(OCCC#N)=O)=C1C
LogP 0.97

SAFETY

Risk and Safety Statements

REACH Registrations Active

2-cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carboxylate price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
aablocks AA01PCNG 2-Cyanoethyl 4-(4-cyano-2-methoxyphenyl)-1,4,5,6-tetrahydro-2,8-dimethyl-5-oxo-1,6-naphthyridine-3-carboxylate 95% 1050477-43-4 100mg $194 2026-05-31 Buy
aablocks AA01PCNG 2-Cyanoethyl 4-(4-cyano-2-methoxyphenyl)-1,4,5,6-tetrahydro-2,8-dimethyl-5-oxo-1,6-naphthyridine-3-carboxylate 95% 1050477-43-4 250mg $271 2026-05-31 Buy
Abosyn 10-4383 2-Cyanoethyl 4-(4-cyano-2-methoxyphenyl)-1,4,5,6-tetrahydro-2,8-dimethyl-5-oxo-1,6-naphthyridine-3-carboxylate ≧95%(Puritymayvarybetweenbatches) 1050477-43-4 200g $2714 2026-05-21 Buy
Product number Packaging Price Buy
AA01PCNG 100mg $194 Buy
AA01PCNG 250mg $271 Buy
10-4383 200g $2714 Buy

2-cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carboxylate Chemical Properties, Uses, Production

Uses

2-Cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carboxylate is a pharmaceutical intermediary ingredient used in the preparation of Finerenone. Finerenone is a non-steroidal, selective salicorticosteroid receptor (MR) antagonist that is used to reduce the risk of serious renal and cardiac problems (e.g., decreased kidney function, end-stage renal disease, cardiovascular death, heart attack, and hospitalisation for heart failure) in patients with chronic kidney disease associated with type 2 diabetes mellitus.

Flammability and Explosibility

Not classified

2-cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

2-cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carboxylate Suppliers

Global Suppliers ( 105)
Supplier Tel Email Country ProdList Advantage
Allikang Pharmaceutical Co., LTD 0573-87390950 13806705416 wzj@alicornpharma.com China 58 58
Shanghai Famo Bio-chemical Technology Company Ltd. 021-36680027 15821745250 fengqiang@famobiotech.com China 494 56
Hunan Furui Biopharma Technology Co., Ltd. 15901640172，19275032510 15901640172 sales03@hn-furui.com China 380 55
Jinan XuanDe Chemical Co., Ltd. 0531-88803958 19862127196 zhangxu@shiningpharm.com China 201 58
YouCoChem (Beijing) Chemical Technology Co., Ltd. 18800159827 youcochem@163.com China 163 50
Hangzhou Cheminspire Technology Co., Ltd. 0571-89081561; 10006559855 info@cheminspire.com China 412 58
Shanghai Changyan Chem & Tech Co., Ltd. 021-20242659 18930833303 sales@changyanchem.cn China 4998 55
Cangzhou Enke Pharma-tech Co., Ltd. 0317-5296180 15533709196 enkepharma@126.com China 2495 55
ChengDu TongChuangYuan Pharmaceutical Co.Ltd 028-83379370 13880556291 tcy@tcypharm.com China 8696 58
Hangzhou Chemtrue Bio-Tech Co.,Ltd. 19967494293 sales@chemtrue-bio.com China 303 58
Supplier Advantage
Allikang Pharmaceutical Co., LTD 58
Shanghai Famo Bio-chemical Technology Company Ltd. 56
Hunan Furui Biopharma Technology Co., Ltd. 55
Jinan XuanDe Chemical Co., Ltd. 58
YouCoChem (Beijing) Chemical Technology Co., Ltd. 50
Hangzhou Cheminspire Technology Co., Ltd. 58
Shanghai Changyan Chem & Tech Co., Ltd. 55
Cangzhou Enke Pharma-tech Co., Ltd. 55
ChengDu TongChuangYuan Pharmaceutical Co.Ltd 58
Hangzhou Chemtrue Bio-Tech Co.,Ltd. 58

View Latest Price from 2-cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carboxylate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carboxylate pictures 2026-06-08 2-cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carboxylate
1050477-43-4
 1kg 99% 1 Jinan Ruitong Biotech Co., Ltd.
2-Cyanoethyl 4-(4-cyano-2-methoxyphenyl)-1,4,5,6-tetrahydro-2,8-dimethyl-5-oxo-1,6-naphthyridine-3-carboxylate pictures 2024-11-26 2-Cyanoethyl 4-(4-cyano-2-methoxyphenyl)-1,4,5,6-tetrahydro-2,8-dimethyl-5-oxo-1,6-naphthyridine-3-carboxylate
1050477-43-4
 1kg 98% 1 ton Nanjing Fred Technology Co., Ltd
2-Cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carboxylate pictures 2024-08-07 2-Cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carboxylate
1050477-43-4
 1Kg ≥99.0% 10 Tons Xuchang Hengsheng Pharmaceutical Co., Ltd
2-cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carboxylate 1,6-Naphthyridine-3-carboxylic acid, 4-(4-cyano-2-methoxyphenyl)-1,4,5,6-tetrahydro-2,8-dimethyl-5-oxo-, 2-cyanoethyl ester 2-Cyanoethyl 4-(4-cyano-2-methoxyphenyl)-1,4,5,6-tetrahydro-2,8-dimethyl-5-oxo-1,6-naphthyridine-3-carboxylate 1,6-Naphthyridine-3-carboxylic acid, 4-(4-cyano-2-methoxyphenyl)-1,4,5,6-tetrahydro-2,8-dimethyl-5-oxo-, 2-cyanoethyl ester (ACI) Finelidone Impurity 52 2-cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-terahydro－1,6－naphthyridine-3-carboxylate 2-cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-l,6-naphthyridine-3-carboxylate 2-cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carboxylate (Finerenone) Fenelunitinib intermediate 1050477-43-4 Intermediate