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4-(1-Acetylpiperazin-4-yl)phenol

4-(1-Acetylpiperazin-4-yl)phenol structure

CAS No.: 67914-60-7

Chemical Name:: 4-(1-Acetylpiperazin-4-yl)phenol

Synonyms: 1-ACETYL-4-(4-HYDROXYPHENYL)PIPERAZINE;AHPP;keto06;TIMTEC-BB SBB003353;Ketoconazole Impurity;LABOTEST-BB LT00440741;Ketoconazole Impurity 13;Branchedchainofketoconazole;4-(4-Acetylpiperazino)phenol;1-Acetyl-4-(4-hydroxyphenyl)pi

CBNumber:: CB4329307

Molecular Formula:: C12H16N2O2

Molecular Weight:: 220.27

MDL Number:: MFCD00044905

MOL File:: 67914-60-7.mol

MSDS File:: SDS

Last updated:2026-01-13 11:19:40

Product description	Number	Pack Size	Price
1-Acetyl-4-(4-hydroxyphenyl)piperazine 98%	511943	25g	$31.5
1-Acetyl-4-(4-hydroxyphenyl)piperazine >98.0%(GC)(T)	A1845	25g	$22
1-Acetyl-4-(4-hydroxyphenyl)piperazine >98.0%(GC)(T)	A1845	250g	$122
1-Acetyl-4-(4-hydroxyphenyl)piperazine	A179045	1g	$55
1-Acetyl-4-(4-hydroxyphenyl)piperazine,99%(Assaybytitration,HPLC) 99%(Assaybytitration,HPLC)	36939	100G	$56
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4-(1-Acetylpiperazin-4-yl)phenol Properties

Melting point	180-185 °C (lit.)
Boiling point	361.21°C (rough estimate)
Density	1.1115 (rough estimate)
vapor pressure	0Pa at 20℃
refractive index	1.6000 (estimate)
storage temp.	-20°C Freezer
solubility	DMSO (Slightly), Methanol (Slightly)
pka	12.18±0.30(Predicted)
form	Powder
color	White to slightly pink or beige
Water Solubility	4.3 g/L (20 ºC)
BRN	795777
InChI	1S/C12H16N2O2/c1-10(15)13-6-8-14(9-7-13)11-2-4-12(16)5-3-11/h2-5,16H,6-9H2,1H3
InChIKey	AGVNLFCRZULMKK-UHFFFAOYSA-N
SMILES	CC(=O)N1CCN(CC1)c2ccc(O)cc2
LogP	0.3
CAS DataBase Reference	67914-60-7(CAS DataBase Reference)
FDA UNII	YH9GD5K5NY
UNSPSC Code	12352100

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P302+P352-P305+P351+P338

target organs

Respiratory system

PPE

dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes

Xi,Xn

Risk Statements

36/37/38-22

Safety Statements

26-36-36/37/39-22

WGK Germany

HS Code

29214910

Storage Class

11 - Combustible Solids

Hazard Classifications

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

NFPA 704

	1
2		0

4-(1-Acetylpiperazin-4-yl)phenol price More Price(28)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	511943	1-Acetyl-4-(4-hydroxyphenyl)piperazine 98%	67914-60-7	25g	$31.5	2023-06-20	Buy
TCI Chemical	A1845	1-Acetyl-4-(4-hydroxyphenyl)piperazine >98.0%(GC)(T)	67914-60-7	25g	$22	2025-07-31	Buy
TCI Chemical	A1845	1-Acetyl-4-(4-hydroxyphenyl)piperazine >98.0%(GC)(T)	67914-60-7	250g	$122	2025-07-31	Buy
TRC	A179045	1-Acetyl-4-(4-hydroxyphenyl)piperazine	67914-60-7	1g	$55	2021-12-16	Buy
Chem-Impex	36939	1-Acetyl-4-(4-hydroxyphenyl)piperazine,99%(Assaybytitration,HPLC) 99%(Assaybytitration,HPLC)	67914-60-7	100G	$56	2021-12-16	Buy

Product number	Packaging	Price	Buy
511943	25g	$31.5	Buy
A1845	25g	$22	Buy
A1845	250g	$122	Buy
A179045	1g	$55	Buy
36939	100G	$56	Buy

4-(1-Acetylpiperazin-4-yl)phenol Chemical Properties,Uses,Production

Chemical Properties

Off-White Solid

Uses

1-Acetyl-4-(4-hydroxyphenyl)piperazine may be used in the preparation of 1-acetyl-4-(4-octadecyloxyphenyl)piperazine. It may also be used in the multi-step synthesis of ketoconazole, its 1,2,4-triazole and thiazole analogs.

General Description

1-Acetyl-4-(4-hydroxyphenyl)piperazine (AHPP), a piperazine derivative, is a structural analog of acetaminophen. Its multi-step preparation using bis-(2-chloroethyl)amine hydrochloride and p-aminophenol as starting materials has been reported.2

Flammability and Explosibility

Not classified

4-(1-Acetylpiperazin-4-yl)phenol Preparation Products And Raw materials

Raw materials

1-Acetyl-4-(4-nitrophenyl)piperazine 4-Chloronitrobenzene PIPERAZINE HEXAHYDRATE 1-(4-Nitrophenyl)piperazine

Preparation Products

Itraconazole

4-(1-Acetylpiperazin-4-yl)phenol Suppliers

Global( 417)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Jinhuan Chemical CO.,LTD.	+86-21-52210535 +8613162045318	sales@jinhchem.com	China	331	58
Hefei Lbao Physical & Chemical Science Co.,Ltd	+1-5184799099	lbaochemicals@gmail.com	China	674	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21599	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29833	58
Xiamen AmoyChem Co., Ltd	+86-86-5926051114 +8615060885618	sales@amoychem.com	China	6369	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49977	58
Shaanxi Dideu Medichem Co. Ltd	+86-29-81148696 +86-17392712697	1022@dideu.com	China	3995	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30229	58

Supplier	Advantage
Shanghai Jinhuan Chemical CO.,LTD.	58
Hefei Lbao Physical & Chemical Science Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Xiamen AmoyChem Co., Ltd	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
Shaanxi Dideu Medichem Co. Ltd	58
Career Henan Chemica Co	58

View Lastest Price from 4-(1-Acetylpiperazin-4-yl)phenol manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-01-24	1-(4-(4-Hydroxyphenyl)piperazin-1-yl)ethanone 67914-60-7	US $0.00 / kg	1kg	98%	Customise	Hefei Lbao Physical & Chemical Science Co.,Ltd
2025-12-24	4-(1-Acetylpiperazin-4-yl)phenol 67914-60-7	US $0.10 / KG	1KG	99.0%	1000 tons	Shaanxi Dideu Medichem Co. Ltd
2025-04-04	4-(1-Acetylpiperazin-4-yl)phenol 67914-60-7	US $0.00-0.00 / kg	1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.

1-(4-(4-Hydroxyphenyl)piperazin-1-yl)ethanone
67914-60-7
US $0.00 / kg
98%
Hefei Lbao Physical & Chemical Science Co.,Ltd

4-(1-Acetylpiperazin-4-yl)phenol
67914-60-7
US $0.10 / KG
99.0%
Shaanxi Dideu Medichem Co. Ltd

4-(1-Acetylpiperazin-4-yl)phenol
67914-60-7
US $0.00-0.00 / kg
98%
Henan Aochuang Chemical Co.,Ltd.

4-(1-Acetylpiperazin-4-yl)phenol Spectrum

4-(1-Acetylpiperazin-4-yl)phenol(67914-60-7)IR

67914-60-7(4-(1-Acetylpiperazin-4-yl)phenol)Related Search:

Acetylacetone Phenol Red PIPERACETAZINE (250 MG) Piperazine N-ACETYL-L-TYROSINE ETHYL ESTER

Acetyl coenzyme A sodium salt Acetyl chloride 4,4'-Diacetylbiphenyl 4-Cyanophenol Tetraacetylethylenediamine

Phenol Ketoconazole Ketoconazole Impurity 2 KetoconazoleN-Oxide 2-(2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOL-1-YL METHYL)-1,3-DIOXOLANE-4-METHANOL

Ketoconazole Impurity 4 cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl-4-methylbenzenesulphonate rac-trans-Ketoconazole

1of4

TIMTEC-BB SBB003353 N-ACETYL-4-HYDROXYPHENYL PIPERAZINE N-ACETYL-4-(4-HYDROXYPHENYL)PIPERAZINE 1-Acetyl-4-(4-hydroxyphenyl)piperazine, 98+% 1-[4-(4-Hydroxyphenyl)piperazin-1-yl]ethanon Piperazine, 1-acetyl-4-(4-hydroxyphenyl)- 1-Acetyl-4-(4-Hydroxy-Phenyl)PiperazineKetoconazole 4-(4-Acetylpiperazino)phenol 4-(4-acetylpiperazin-1-yl)phenol 1-Acety-(4-hyroxypheny)piperazine 1-(4-hydroxyphenyl)-4-acetylpiperazine 1-[4-(4-Hydroxyphenyl)-1-piperazinyl]ethanone Ketoconazole IMpurity (1-Acetyl-4-(4-hydroxyphenyl)piperazine) Ethanone, 1- [4- (4- hydroxyphenyl) - 1- piperazinyl] - keto06 1-ACETYL-4-(4-HYDROXY PHENYL)PIPERAZINE (BRANCHED CHAIN) (PIPERAZINE RING IN STRUCTURE) 1-Acetyl-4-(HydroxyPhenyl)Piprazine Ketoconazole Impurity 13 (1-Acetyl-4-(4-hydroxyphenyl)piperazine) 1-Acetyl-4-(4-hydroxyphenyl)piperazine (AHPP) Ketoconazole Impurity 4-(4-tert-butylphenyl)-2-(1-methyl-3-indolyl)-4-oxobutanoic acid 1-Acetyl-4-(4-hydroxyphenyl) piperazie Ketoconazole Impurity 13 Branchedchainofketoconazole 1-ACETYL-P-HYDROXYPHENYL PIPERAZINE 1-ACETYL-(4-HYDROXYPHENYL)PIPERAZINE 1-ACETYL-4-(4-HYDROXYLPHENYL)PIPERAZINE 1-ACETYL-4-(4'-HYDROXYPHENYL)PIPERAZINE 1-ACETYL-4-(4-HYDROXYPHENYL)PIPERAZINE 1-[4-(4-HYDROXY-PHENYL)-PIPERAZIN-1-YL]-ETHANONE 1-[4-(4-HYDROXYPHENYL)PIPERAZINO]ETHAN-1-ONE 4-(1-Acetylpiperazin-4-yl)phenol 4-(4-ACETYL-1-PIPERAZINYL)PHENOL AHPP LABOTEST-BB LT00440741 4-(4-Acetyl-1-piperazino)phenol 4-(4-acetylpiperazin-4-yl)phenol 1-Acetyl-4-(4-hydroxyphenyl)pi 1-ACETYL-4-(4-HYDROXPHENYL)PIPERAZINE 1-Acetyl-4-(p-hydroxyphenyl)piperazine 1-Acetyl-4-(4-hydroxyphenyl)piperaz 1-Acetyl-4-(4-hydroxyphenyl)piperazine > 1-ACETYL-4-(4-HYDROXYPHENYL)PIPERAZINE (4AHPP) 4-AHPP : 1-Acetyl-4-(4-Hydroxy Phenyl) Piperazine 1-Acetyl-4-(4-Hydroxyphenyl)Piperzine 1-Acetyt-4-(4-Hydroxyphenyl) Piperazine N-AcetyI-(4-Hydroxy Phenyl) Piperazine n-Acetyl 4-(4-Hydroxy phenyl) Piperizine 67914-60-7 67914-60-4 C12H16O2N2 Piperazines Heterocyclic Building Blocks Building Blocks Piperaizine Miscellaneous Chemical Amines Amines