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tioxazafen

CAS No.
330459-31-9
Chemical Name:
tioxazafen
Synonyms
tioxazafen;Tioxazafen Solution;Tioxazafen, 10 mM in DMSO;3-phenyl-5-(2-thienyl)-1,2,4-oxadiazole;1,2,4-Oxadiazole, 3-phenyl-5-(2-thienyl)-;3-phenyl-5-thiophen-2-yl-1,2,4-oxadiazole;3-phenyl-5-(thiophene-2-yl)-1,2,4-diazole;soy,corn,broad-spectrum,Parasite,seed,Nematicide,Tioxazafen,Inhibitor,disubstituted,cotton,oxadiazole,inhibit
CBNumber:
CB43352564
Molecular Formula:
C12H8N2OS
Molecular Weight:
228.27
MDL Number:
MFCD00760257
MOL File:
330459-31-9.mol
MSDS File:
SDS
Last updated:2026-07-31 15:25:14
Product description Number Pack Size Price
Tioxazafen FNA45931 5mg $921.75
Tioxazafen FNA45931 10mg $1474.8
Tioxazafen FNA45931 25mg $2404.5
Tioxazafen FNA45931 50mg $3847.5
Tioxazafen CS-0120932 5mg $97
More product size

tioxazafen Properties

Boiling point 390.8±34.0 °C(Predicted)
Density 1.277±0.06 g/cm3(Predicted)
vapor pressure 0-0Pa at 15-35℃
pka -1.79±0.20(Predicted)
form Solid
color Off-white to light yellow
LogP 4.13 at pH6.71-7.87
FDA UNII 45442MUI4L
EPA Substance Registry System Tioxazafen (330459-31-9)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)Environment (GHS09)
GHS07,GHS09
Signal word  Warning
Hazard statements  H315-H410
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P273-P391-P501
REACH Registrations Inactive

tioxazafen price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth FNA45931 Tioxazafen 330459-31-9 5mg $921.75 2026-06-04 Buy
Biosynth FNA45931 Tioxazafen 330459-31-9 10mg $1474.8 2026-06-04 Buy
Biosynth FNA45931 Tioxazafen 330459-31-9 25mg $2404.5 2026-06-04 Buy
Biosynth FNA45931 Tioxazafen 330459-31-9 50mg $3847.5 2026-06-04 Buy
ChemScene CS-0120932 Tioxazafen 330459-31-9 5mg $97 2026-06-04 Buy
Product number Packaging Price Buy
FNA45931 5mg $921.75 Buy
FNA45931 10mg $1474.8 Buy
FNA45931 25mg $2404.5 Buy
FNA45931 50mg $3847.5 Buy
CS-0120932 5mg $97 Buy

tioxazafen Chemical Properties,Uses,Production

Uses

Tioxazafen is a disubstituted oxadiazole and a broad-spectrum seed treatment nematicide. Tioxazafen is designed to provide consistent broad-spectrum control of nematodes in corn, soy, and cotton[1].

Definition

ChEBI: Tioxazafen is a 1,2,4-oxadizole in which the hydrogens at positions 3 and 5 have been replaced by phenyl and thiophen-2-yl groups, respectively. It is used as a broad spectrum nematicidal seed treatment. It has a role as a nematicide and an agrochemical. It is a member of thiophenes and a 1,2,4-oxadiazole.

Production Methods

Commercial production begins with benzonitrile and thiophene based intermediates, which are converted into amidoximes and thiophene carboximidamides. These precursors undergo cyclisation reactions to form the 1,2,4 oxadiazole ring system, followed by coupling of the phenyl and thiophene groups to yield the disubstituted oxadiazole structure. The crude product is then purified by recrystallisation or solvent extraction to remove residual reactants and by products, producing a stable technical material.

Mechanism of action

Broad-spectrum. It acts through interaction with a nematode-specific insertion of the L3 subunit of the mitochondrial ribosome, leading to disruption of ribosomal translation in nematodes.

References

[1] Urszula Slomczynska, et al. Tioxazafen: A New Broad-Spectrum Seed Treatment Nematicide. Discovery and Synthesis of Crop Protection Products. 2015, Chapter 10: pp 129-147.

Pesticide Type

Nematicide

5271-67-0
613-92-3
330459-31-9
Synthesis of tioxazafen from 2-Thiophenecarbonyl chloride and BENZAMIDOXIME HYDROCHLORIDE
Global( 41)Suppliers
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Hangzhou FandaChem Co.,Ltd.
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XIAMEN AMITY INDUSTRY AND TRADE CO., LTD.
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ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
+86-15225627621 +86-13213167925 jiuyitime@fdachem.com China 16505 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131885 58
Tianjin Zhongtian Xinchuang Technology Co., Ltd. 13312191509 1932163312@qq.com China 235 58

Related articles

View Lastest Price from tioxazafen manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Tioxazafen pictures 2026-07-15 Tioxazafen
330459-31-9
$43.00-137.00 99.71% 10g TargetMol Chemicals Inc.
Tioxazafen pictures 2026-07-15 Tioxazafen
330459-31-9
$43.00-137.00 99.71% 10g TargetMol Chemicals Inc.
  • Tioxazafen pictures
  • Tioxazafen
    330459-31-9
  • $43.00-137.00
  • 99.71%
  • TargetMol Chemicals Inc.
  • Tioxazafen pictures
  • Tioxazafen
    330459-31-9
  • $43.00-137.00
  • 99.71%
  • TargetMol Chemicals Inc.

tioxazafen Spectrum

330459-31-9(tioxazafen)Related Search:

tioxazafen 3-phenyl-5-thiophen-2-yl-1,2,4-oxadiazole Tioxazafen Solution 1,2,4-Oxadiazole, 3-phenyl-5-(2-thienyl)- soy,corn,broad-spectrum,Parasite,seed,Nematicide,Tioxazafen,Inhibitor,disubstituted,cotton,oxadiazole,inhibit 3-phenyl-5-(2-thienyl)-1,2,4-oxadiazole Tioxazafen, 10 mM in DMSO 3-phenyl-5-(thiophene-2-yl)-1,2,4-diazole 330459-31-9