1,3-Dimethyladamantane
- CAS No.
- 702-79-4
- Chemical Name:
- 1,3-Dimethyladamantane
- Synonyms
- Dimethyladamantane;1,3-DIMETHYL ADAMANTINE;MeMantine Related CoMpound A;Memantine USP RC A;1,3-Dimethyladamanta;1, 3-dimethylfungane;3-Dimethyl Adamantane;Adamantane Impurity A;Memantine intermediate;1,5-Dimethyladamantane
- CBNumber:
- CB4335302
- Molecular Formula:
- C12H20
- Molecular Weight:
- 164.29
- MDL Number:
- MFCD00074755
- MOL File:
- 702-79-4.mol
| Melting point | -30 °C |
|---|---|
| Boiling point | 201.5 °C |
| Density | 0.886 g/mL at 25 °C (lit.) |
| refractive index |
n |
| Flash point | 127 °F |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | clear liquid |
| color | Colorless to Almost colorless |
| Specific Gravity | 0.886 |
| Stability | Stable. Incompatible with strong oxidizing agents. Flammable. |
| InChI | InChI=1S/C12H20/c1-11-4-9-3-10(5-11)7-12(2,6-9)8-11/h9-10H,3-8H2,1-2H3 |
| InChIKey | CWNOIUTVJRWADX-UHFFFAOYSA-N |
| SMILES | C12(C)CC3CC(CC(C)(C3)C1)C2 |
| CAS DataBase Reference | 702-79-4(CAS DataBase Reference) |
| FDA UNII | 96G4OD5Z59 |
| NIST Chemistry Reference | Adamantane, 1,3-dimethyl-(702-79-4) |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
1,3-Dimethyladamantane price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHR2449 | Memantine Related Compound A Pharmaceutical Secondary Standard; Certified Reference Material | 702-79-4 | 100MG | $683.05 | 2025-07-31 | Buy |
| Sigma-Aldrich | 187836 | 1,3-Dimethyladamantane ≥99% | 702-79-4 | 5g | $148.2 | 2025-07-31 | Buy |
| Sigma-Aldrich | 1380513 | Memantine Related Compound A United States Pharmacopeia (USP) Reference Standard | 702-79-4 | 50mg | $1300 | 2025-07-31 | Buy |
| TCI Chemical | D1081 | 1,3-Dimethyladamantane >99.0%(GC) | 702-79-4 | 5mL | $54 | 2025-07-31 | Buy |
| TCI Chemical | D1081 | 1,3-Dimethyladamantane >99.0%(GC) | 702-79-4 | 25mL | $159 | 2025-07-31 | Buy |
1,3-Dimethyladamantane Chemical Properties,Uses,Production
Chemical Properties
clear colourless liquid
Uses
1,3-Dimethyladamantane is a dimethylated adamantane derivative. Memantine impurity A. Memantine Related Compound A (1,3-Dimethyladamantane).
Application
1,3-Dimethyladamantane was used in the synthesis of 1,3-dibromo-5,7-dimethyladamantane.
Definition
ChEBI: 1,3-dimethyladamantane is a polycyclic alkane and a member of adamantanes. It derives from a hydride of an adamantane.
General Description
1,3-Dimethyladamantane undergoes C-H insertion reaction with phenylchlorocarbene. It reacts with with molecular oxygen in the presence of N-hydroxyphthalimide combined with cobalt salts to yield 3,5-dimethyladamantan-1-ol and 5,7-dimethyladamantane-1,3-diol.
Synthesis
941-37-7
702-79-4
GENERAL METHODS: A thiocarbonate solution was prepared by dissolving 5 g (107 mg, 0.200 mmol) of 1-bromo-3,5-dimethyladamantane in CPME (0.5 mL). Subsequently, a solution of n-Bu3SnH (75.7 mg, 0.260 mmol) and AIBN (6.6 mg, 0.040 mmol) in CPME (1.5 mL) was slowly added dropwise by syringe pump to the above thiocarbonate solution, and the reaction lasted for 30 min at 90 °C. After completion of the reaction, the mixture was continued to be stirred at the same temperature for 30 min, followed by concentration. The residue was purified by 10% w/w K2CO3-silica gel fast column chromatography using gradient elution (hexane → hexane/EtOAc = 100/1 → 50/1 → 20/1) to afford 6 g of cis-consistently cyclized product (53.6 mg, 0.140 mmol, 70% yield) and a mixture of cis- and trans-consistently diastereoisomers (22.0 mg. 0.0572 mmol, 29% yield, cis-trans ratio of 2.8:1). For spectral analysis, these isomers were separated by repeated column chromatography.
References
[1] Tetrahedron, 2013, vol. 69, # 10, p. 2251 - 2259
[2] Organic Letters, 2008, vol. 10, # 4, p. 533 - 536
[3] Journal of Organic Chemistry, 1983, vol. 48, # 16, p. 2762 - 2765
1,3-Dimethyladamantane Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jinan Qinmu Fine Chemical Co.,Ltd. | +8618660799346 | sales@qinmuchem.com | China | 1008 | 58 |
| Nanjing Shunxiang Pharmaceutical Technology Co.,Ltd. | +86-86-02586819868 +8613913839793 | sales@jinchemical.com | China | 23 | 58 |
| Hebei Mujin Biotechnology Co.,Ltd | +8613288715578 | sales@hbmojin.com | China | 12464 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5251 | 58 |
| Hebei Fengjia New Material Co., Ltd | +86-0311-87836622 +86-18712993135 | sales01@tairunfaz.com | China | 8051 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| Shandong Huisheng Import & Export Co., Ltd. | +86-13176845580 | da@zhongda-biotech.com | China | 232 | 58 |
| Anhui Zhongda Biotechnology Co., Ltd | +8619956560829 | justine@zhongda-biotech.com | China | 286 | 58 |
| Anhui Zhongda Biotechnology Co., Ltd | +8615689548120 | linda@zhongda-biotech.com | China | 193 | 58 |
| Anhui Ruihan Technology Co., Ltd | +8617756083858 | daisy@anhuiruihan.com | China | 973 | 58 |
View Lastest Price from 1,3-Dimethyladamantane manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-08-30 | 1,3-Dimethyladamantane
702-79-4
|
0.99 | RongNa Biotechnology Co.,Ltd | ||||
 |
2025-08-29 | 1,3-Dimethyladamantane
702-79-4
|
US $0.00-0.00 / kg | 1kg | 99% | 1000 | Hebei Junhua Import and Export Co., LTD | |
 |
2025-08-28 | 1,3-Dimethyladamantane
702-79-4
|
US $5.00-0.50 / KG | 1KG | 99% hplc | 500TONS | Wuhan JiyunZen Tech Co., Ltd. |
-
- 1,3-Dimethyladamantane
702-79-4
- 0.99
- RongNa Biotechnology Co.,Ltd
-
- 1,3-Dimethyladamantane
702-79-4
- US $0.00-0.00 / kg
- 99%
- Hebei Junhua Import and Export Co., LTD
-
- 1,3-Dimethyladamantane
702-79-4
- US $5.00-0.50 / KG
- 99% hplc
- Wuhan JiyunZen Tech Co., Ltd.
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