Simmitecan Hydrochloride
- CAS No.
- 1247847-78-4
- Chemical Name:
- Simmitecan Hydrochloride
- Synonyms
- Simmitecan Hydrochloride
- CBNumber:
- CB43358869
- Molecular Formula:
- C34H39ClN4O6
- Molecular Weight:
- 635.14966
- MDL Number:
- MOL File:
- 1247847-78-4.mol
- MSDS File:
- SDS
| FDA UNII | T4H02O147G |
|---|---|
| NCI Drug Dictionary | simmitecan hydrochloride |
Simmitecan Hydrochloride price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | XZB84778 | Simmitecan | 1247847-78-4 | 250mg | $1077.5 | 2026-06-05 | Buy |
| ChemScene | CS-0027397 | Simmitecan hydrochloride | 1247847-78-4 | 1mg | $789 | 2026-06-04 | Buy |
| ChemScene | CS-0027397 | Simmitecan hydrochloride | 1247847-78-4 | 5mg | $1969 | 2026-06-04 | Buy |
| ChemScene | CS-0027397 | Simmitecan hydrochloride | 1247847-78-4 | 10mg | $2952 | 2026-06-04 | Buy |
| aablocks | AA021MPU | Simmitecan | 1247847-78-4 | 1mg | $728 | 2026-06-01 | Buy |
Simmitecan Hydrochloride Chemical Properties, Uses, Production
Uses
Simmitecan hydrochloride, a 9-substituted lipophilic Camptothecin (HY-16560) derivative, is a potent topoisomerase I inhibitor. Simmitecan hydrochloride is an anticancer agent[1][2].
in vivo
Simmitecan hydrochloride (3.75, 7.5 and 15 mg/kg, i.v. bolus) shows mean elimination half-life t1/2 of approximately 1.4 h in SD rats[2].
References
[1] Rini B, et al. A phase I/II study of lenalidomide in combination with sunitinib in patients with advanced or metastatic renal cell carcinoma. Ann Oncol. 2014 Sep;25(9):1794-1799. DOI:10.1093/annonc/mdu212
[2] Hu ZY, et al. Pharmacokinetic evaluation of the anticancer prodrug simmitecan in different experimental animals. Acta Pharmacol Sin. 2013 Nov;34(11):1437-48. DOI:10.1038/aps.2013.74
Simmitecan Hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Simmitecan Hydrochloride Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Zhen Li Biological Technology Co., Ltd | 021-16621358918; 18516310516;16621358918;13045646768 | zhenlipharma888@163.com | China | 19060 | 58 |
| Shochem(Shanghai)Co.,Ltd | +86-021-51783479 13816874662 | info@shochem.com | China | 300 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Shochem(Shanghai) Co.,Ltd | 86-21-50800795 | info@shochem.com | CHINA | 286 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Shanghai Amole Biotechnology Co., Ltd. | 13370042665 18916960931 | 2596183085@qq.com | China | 17234 | 58 |
View Latest Price from Simmitecan Hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-27 | Simmitecan hydrochloride
1247847-78-4
|
$588.00-2570.00 | 99.53% | 10g | TargetMol Chemicals Inc. |
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- Simmitecan hydrochloride
1247847-78-4
- $588.00-2570.00
- 99.53%
- TargetMol Chemicals Inc.
