3-(4-pyridinyl)-1,2,4-Triazolo[3,4-b][1,3,4]thiadiazole 3-(Pyridin-4-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
- CAS No.
- 133847-06-0
- Chemical Name:
- 3-(4-pyridinyl)-1,2,4-Triazolo[3,4-b][1,3,4]thiadiazole 3-(Pyridin-4-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
- Synonyms
- YU142670;YU142670 >=98% (HPLC);1,2,4-Triazolo[3,4-b][1,3,4]thiadiazole, 3-(4-pyridinyl)-;3-(4-pyridinyl)-1,2,4-Triazolo[3,4-b][1,3,4]thiadiazole 3-(Pyridin-4-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
- CBNumber:
- CB43365159
- Molecular Formula:
- C8H5N5S
- Molecular Weight:
- 203.22
- MDL Number:
- MOL File:
- 133847-06-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
3-(4-pyridinyl)-1,2,4-Triazolo[3,4-b][1,3,4]thiadiazole 3-(Pyridin-4-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole Properties
| storage temp. | 2-8°C |
|---|---|
| solubility | DMSO: 2mg/mL, clear (warmed) |
| form | powder |
| color | white to light brown |
| InChIKey | HRBYAJQMVADJHW-UHFFFAOYSA-N |
| SMILES | C12=NN=C(C3=CC=NC=C3)N1N=CS2 |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
3-(4-pyridinyl)-1,2,4-Triazolo[3,4-b][1,3,4]thiadiazole 3-(Pyridin-4-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | IFA84706 | YU142670 | 133847-06-0 | 25mg | $801.75 | 2026-06-04 | Buy |
| Biosynth | IFA84706 | YU142670 | 133847-06-0 | 50mg | $1283.5 | 2026-06-04 | Buy |
| Biosynth | IFA84706 | YU142670 | 133847-06-0 | 100mg | $1785 | 2026-06-04 | Buy |
| ChemScene | CS-0077654 | YU142670 99.40% | 133847-06-0 | 1mg | $65 | 2026-06-04 | Buy |
| ChemScene | CS-0077654 | YU142670 99.40% | 133847-06-0 | 5mg | $135 | 2026-06-04 | Buy |
3-(4-pyridinyl)-1,2,4-Triazolo[3,4-b][1,3,4]thiadiazole 3-(Pyridin-4-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole Chemical Properties,Uses,Production
Description
YU142670 is a novel selective inhibitor against OCRL1/INPP5F and OCRL2/INPP5B by targeting OCRL catalytic domain.
Uses
YU142670 is an inhibitor of OCRL/INPP5B with IC50 values of 0.71 μM and 1.78 μM respectively[1].
References
[1] Mills SJ, et al. Crystal Structures of Type-II Inositol Polyphosphate 5-Phosphatase INPP5B with Synthetic Inositol Polyphosphate Surrogates Reveal New Mechanistic Insights for the Inositol 5-Phosphatase Family. Biochemistry. 2016 Mar 8;55(9):1384-97. DOI:10.1021/acs.biochem.5b00838
3-(4-pyridinyl)-1,2,4-Triazolo[3,4-b][1,3,4]thiadiazole 3-(Pyridin-4-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole Preparation Products And Raw materials
Raw materials
Preparation Products
3-(4-pyridinyl)-1,2,4-Triazolo[3,4-b][1,3,4]thiadiazole 3-(Pyridin-4-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Guangzhou Isun Pharmaceutical Co., Ltd | 020-39119399 18927568969 | isunpharm@qq.com | China | 4773 | 55 |
| Shanghai SunSyn Pharmaceutical Co., Ltd. | 021-18621020637 18621020637 | sales@sunsynpharma.com | China | 297 | 55 |
| Guangzhou Younan Technology Co., Ltd | 020-82000279 18988941452 | YN_research@163.com | China | 2984 | 58 |
| Energy Chemical | 400-0056266 | marketing1@energy-chemical.com | China | 44927 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd | 025-5885952 15955137747 | sales@aikonchem.com | China | 8012 | 58 |
| TargetMol Chemicals Inc. | 13564774135 | marketing@targetmol.com | United States | 19950 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38999 | 58 |





