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ARQ-531

ARQ-531 structure

CAS No.: 2095393-15-8

Chemical Name:: ARQ-531

Synonyms: Nemtabrutinib;ARQ-531;ARQ 531, 10 mM in DMSO;Nemtabrutinib (ARQ-531);Nemtabrutinib (ARQ 531) ，S8711;Btk,MK1026,ARQ-531,MK 1026,Inhibitor,inhibit,ARQ 531,Bruton tyrosine kinase,MK-1026,ARQ531;(2-chloro-4-phenoxyphenyl)-[4-[[(3R,6S)-6-(hydroxymethyl)oxan-3-yl]amino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]methanone;D-erythro-Hexitol, 1,5-anhydro-2-[[5-(2-chloro-4-phenoxybenzoyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]-2,3,4-trideoxy-;D-erythro-Hexitol, 1,5-anhydro-2-[[5-(2-chloro-4-phenoxybenzoyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]-2,3,4-trideoxy- (ACI);(2-chloro-4-phenoxyphenyl)(4-(((3R,6S)-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-5-yl)methanone

CBNumber:: CB43384749

Molecular Formula:: C25 H23 Cl N4 O4

Molecular Weight:: 0

MDL Number:: MFCD31692379

MOL File:: 2095393-15-8.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 05:47:19

Product description	Number	Pack Size	Price
ARQ 531 ≥98%	30165	1mg	$28
ARQ 531 ≥98%	30165	5mg	$97
ARQ 531 ≥98%	30165	10mg	$165
ARQ 531 ≥98%	30165	25mg	$241
1,5-Anhydro-2-[[5-(2-chloro-4-phenoxybenzoyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]-2,3,4-trideoxy-D-erythro-hexitol 99%	AA01EO5M	1mg	$18

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ARQ-531 Properties

storage temp.	Store at -20°C
solubility	DMSO : ≥ 50 mg/mL (104.40 mM)
form	Solid
color	White to off-white
InChIKey	JSFCZQSJQXFJDS-OYFFHAMFNA-N
SMILES	C(C1=CC=C(OC2=CC=CC=C2)C=C1Cl)(C1C2C(N[C@@H]3CC[C@@H](CO)OC3)=NC=NC=2NC=1)=O \|&1:19,22,r\|
FDA UNII	JTZ51LIXN4

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338

ARQ-531 price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	30165	ARQ 531 ≥98%	2095393-15-8	1mg	$28	2026-04-30	Buy
Cayman Chemical	30165	ARQ 531 ≥98%	2095393-15-8	5mg	$97	2026-04-30	Buy
Cayman Chemical	30165	ARQ 531 ≥98%	2095393-15-8	10mg	$165	2026-04-30	Buy
Cayman Chemical	30165	ARQ 531 ≥98%	2095393-15-8	25mg	$241	2026-04-30	Buy
aablocks	AA01EO5M	1,5-Anhydro-2-[[5-(2-chloro-4-phenoxybenzoyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]-2,3,4-trideoxy-D-erythro-hexitol 99%	2095393-15-8	1mg	$18	2026-05-30	Buy

Product number	Packaging	Price	Buy
30165	1mg	$28	Buy
30165	5mg	$97	Buy
30165	10mg	$165	Buy
30165	25mg	$241	Buy
AA01EO5M	1mg	$18	Buy

ARQ-531 Chemical Properties,Uses,Production

Uses

ARQ 531 is a reversible non-covalent inhibitor of Bruton’s Tyrosine Kinase (BTK),with IC50s of 0.85 nM and 0.39 nM for WT-BTK and C481S-BTK, respectively. It shows strong target inhibition in TMD8 cell line.

ARQ-531 Preparation Products And Raw materials

Raw materials

Preparation Products

ARQ-531 Suppliers

Global( 81)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32466	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471;	sales@sarms4muscle.com	China	10473	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6391	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8467	58
Zibo Hangyu Biotechnology Development Co., Ltd	+86-0533-2185556 +8615965530500	nickzhang@hangyubiotech.com	China	9951	58
HANGZHOU LEAP CHEM CO., LTD.	+86-571-87711850	market18@leapchem.com	China	43333	58
Sichuan Biosynce Pharmatech Co., Ltd.	+8619950309693	diane@biosynce.com	China	4871	58
Aladdin Scientific		tp@aladdinsci.com	United States	57505	58
Suzhou ARTK Medchem Co., Ltd.	+8618118463618	sales1@artkmedchem.com	China	39021	58
Wuhan Jingkang en Biomedical Technology Co., Ltd	+8613720134139	orders@jknbiochem.com	China	5221	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
Zhejiang J&C Biological Technology Co.,Limited	58
InvivoChem	58
Wuhan Topule Biopharmaceutical Co., Ltd	58
Zibo Hangyu Biotechnology Development Co., Ltd	58
HANGZHOU LEAP CHEM CO., LTD.	58
Sichuan Biosynce Pharmatech Co., Ltd.	58
Aladdin Scientific	58
Suzhou ARTK Medchem Co., Ltd.	58
Wuhan Jingkang en Biomedical Technology Co., Ltd	58

ARQ-531 Spectrum

ARQ-531(2095393-15-8)¹HNMR

ARQ-531 (2-chloro-4-phenoxyphenyl)-[4-[[(3R,6S)-6-(hydroxymethyl)oxan-3-yl]amino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]methanone 1,?5-?Anhydro-?2-?[[5-?(2-?chloro-?4-?phenoxybenzoyl)?-?7H-?pyrrolo[2,?3-?d]?pyrimidin-?4-?yl]?amino]?-?2,?3,?4-?trideoxy-?D-?erythro-?hexitol D-erythro-Hexitol, 1,5-anhydro-2-[[5-(2-chloro-4-phenoxybenzoyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]-2,3,4-trideoxy- (2-Chloro-4-phenoxyphenyl)(4-(((3R,6S)-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)amino)-3H-pyrrolo[2,3-d]pyrimidin-5-yl)methanone D-erythro-Hexitol, 1,5-anhydro-2-[[5-(2-chloro-4-phenoxybenzoyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]-2,3,4-trideoxy- (ACI) (2-chloro-4-phenoxyphenyl)(4-(((3R,6S)-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-5-yl)methanone Nemtabrutinib (ARQ-531) Btk,MK1026,ARQ-531,MK 1026,Inhibitor,inhibit,ARQ 531,Bruton tyrosine kinase,MK-1026,ARQ531 ARQ 531, 10 mM in DMSO Nemtabrutinib (ARQ 531) ，S8711 Nemtabrutinib 2095393-15-8 GS ARQ-531