OLIGOMYCIN C
- CAS No.
- 11052-72-5
- Chemical Name:
- OLIGOMYCIN C
- Synonyms
- OLIGOMYCIN C;Oligmycin C;12-Deoxyoligomycin A;Oligomycin A, 12-deoxy-;OLIGOMYCIN C, STREPTOMYCES DIASTATOCHROMOGENES;Spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-[2H]pyran]-3,9,13-trione,22-ethyl-3',4',5',6'-tetrahydro-7,11,15-trihydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethyl-,(1R,2'R,4E,5'S,6S,6'S,7R,8S,10R,11R,12S,14S,15S,16R,18E,20E,22R,25S,28S,29R)-;Spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-[2H]pyran]-3,9,13-trione, 22-ethyl-3',4',5',6'-tetrahydro-7,11,15-trihydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethyl-, (1R,2'R,4E,5'S,6S,6'S,7R,8S,10R,11S,12S,14S,15S,16R,18E,20E,22R,25S,28S,29R)-
- CBNumber:
- CB4354053
- Molecular Formula:
- C45H74O10
- Molecular Weight:
- 775.06
- MDL Number:
- MFCD32182610
- MOL File:
- 11052-72-5.mol
- MSDS File:
- SDS
Product description | Number | Pack Size | Price |
Oligomycin C ≥95% | 19162 | 1mg | $364 |
Oligomycin C ≥95% | 19162 | 5mg | $1088 |
Oligomycin C | O6154-02 | 1mg | $523 |
OligomycinC | O532985 | 1mg | $325 |
OLIGOMYCIN C 95.00% | API0003674 | 1MG | $617.4 |
More product size |
Boiling point | 876.2±65.0 °C(Predicted) |
---|---|
Density | 1.091 g/cm3 |
storage temp. | −20°C |
solubility | Soluble in DMSO |
form | White to off-white powder. |
pka | 13.49±0.70(Predicted) |
Merck | 13,6902 |
EWG's Food Scores | 1 |
FDA UNII | 4F7MA81184 |
OLIGOMYCIN C price More Price(10)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Cayman Chemical | 19162 | Oligomycin C ≥95% | 11052-72-5 | 1mg | $364 | 2024-03-01 | Buy |
Cayman Chemical | 19162 | Oligomycin C ≥95% | 11052-72-5 | 5mg | $1088 | 2024-03-01 | Buy |
Usbiological | O6154-02 | Oligomycin C | 11052-72-5 | 1mg | $523 | 2021-12-16 | Buy |
TRC | O532985 | OligomycinC | 11052-72-5 | 1mg | $325 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0003674 | OLIGOMYCIN C 95.00% | 11052-72-5 | 1MG | $617.4 | 2021-12-16 | Buy |
OLIGOMYCIN C Chemical Properties,Uses,Production
Description
Oligomycins are macrolides created by Streptomyces species that can be toxic to other organisms. Different oligomycin isomers are highly specific for the disruption of mitochondrial metabolism. Oligomycin C is a minor component of the oligomycin complex that acts as an inhibitor of the mitochondrial F1FO-ATP synthase. Inhibition of the ATP synthase by oligomycins leads to cell death.
Uses
Oligomycin C, a minor component of the oligomycin complex isolated from selected strains of Streptomyces, is an inhibitor of mitochondrial F1F0-ATPase. It makes cells more susceptible to cell death, and also leads to a switch in the death mode from apoptosis to necrosis.
Uses
Oligomycin C is an ATP synthetase and RVD inhibitor.
Safety Profile
A poison by intraperitoneal route.When heated to decomposition it emits acrid smoke andirritating vapors
IC 50
Macrolide
References
[1]. yang p w, li m g, zhao j y, et al. oligomycins a and c, major secondary metabolites isolated from the newly isolated strain streptomyces diastaticus[j]. folia microbiologica, 2010, 55(1): 10-16.
[2]. marton a, mihalik r, bratincsák a, et al. apoptotic cell death induced by inhibitors of energy conservation[j]. european journal of biochemistry, 1997, 250(2): 467-475.
OLIGOMYCIN C Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32434 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39031 | 58 |
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd | +8618791163155 | 18791163155@163.com | China | 3402 | 58 |
Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53900 | 58 |
Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696,15000506266 15000506266 | China | 4667 | 55 | |
Shanghai Haozhixiang Biotechnology Co., Ltd | 526763801 13301653310 | 526763801@qq.com | China | 8866 | 55 |
Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9803 | 58 |
Lynnchem | 86-(0)29-85992781 17792393971 | info@lynnchem.com | China | 4587 | 58 |
View Lastest Price from OLIGOMYCIN C manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2025-08-21 | Oligomycin C
11052-72-5
|
US $891.00 / mg | 10g | TargetMol Chemicals Inc. |
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- Oligomycin C
11052-72-5
- US $891.00 / mg
- TargetMol Chemicals Inc.
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