ALPHA-HEMOLYSIN
- CAS No.
- 94716-94-6
- Chemical Name:
- ALPHA-HEMOLYSIN
- Synonyms
- α-HeMolysin;ALPHA-TOXIN;ALPHA-HEMOLYSIN;STAPHYLOCOCCUS AUREUS;Staphylococcus piscifermentans;ALPHA-TOXIN, STAPHYLOCOCCUS AUREUS;α-Hemolysin (Staphylococcus aureus);α-HemolysinfromStaphylococcusaureus;α-hemolysin from staphylococcus aureus;A-HEMOLYSIN FROM STAPHYLOCOCCUS AUREUS
- CBNumber:
- CB4384087
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00130489
- MOL File:
- Mol file
- MSDS File:
- SDS
- TDS File:
- TDS
| storage temp. | 2-8°C |
|---|---|
| solubility | H2O: soluble0.49 - 0.51mg/mL |
| form | lyophilized powder |
| color | White to off-white |
| biological source | Staphylococcus aureus |
| Water Solubility | H2O: soluble 0.49-0.51mg/mL |
| Specific Activity | ≥10,000units/mg protein |
| FDA UNII | 3CI74JWB53 |
| UNSPSC Code | 12352202 |
| NACRES | NA.56 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H371 |
| Precautionary statements | P260-P264-P270-P302+P352-P305+P351+P338-P308+P311 |
| target organs | Lungs,Blood |
| PPE | Eyeshields, Gloves, type N95 (US) |
| Hazard Codes | Xn |
| Risk Statements | 22-21/22 |
| Safety Statements | 36-36/37 |
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 2 |
ALPHA-HEMOLYSIN price More Price(2)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | H9395 | α-Hemolysin from Staphylococcus aureus lyophilized powder, Protein ~60?% by Lowry, ≥10,000?units/mg protein | 94716-94-6 | 0.5MG | $500 | 2026-04-30 | Buy |
| Sigma-Aldrich | H9395 | α-Hemolysin from Staphylococcus aureus lyophilized powder, Protein ~60 % by Lowry, ≥10,000 units/mg protein | 94716-94-6 | 1mg | $941 | 2026-04-30 | Buy |
ALPHA-HEMOLYSIN Chemical Properties, Uses, Production
Uses
ALPHA-HEMOLYSIN was used in a study to test the efflux pump and haemolysin activity of Escherichia coli of dairy origin. It was also used to test its adaptation to benzalkonium chloride and the effect of ciprofloxacin on biofilm formation.
Uses
α-Hemolysin was used in a study to test the efflux pump and haemolysin activity of Escherichia coli of dairy origin. It was also used to test its adaptation to benzalkonium chloride and the effect of ciprofloxacin on biofilm formation.
General Description
α-Hemolysin, a pore-forming cytotoxin is an extracellular protein secreted by most strains of pathogenicStaphylococcus aureus. It is secreted as a water-soluble monomer and is a small β-barrel protein.
Biochem/physiol Actions
α-Hemolysin is selectively hemolytic and the monomeric form binds to a membrane and specific receptors are not required for binding. Upon binding to biological membranes and/or artificial membranes, self-oligomerization occurs, resulting in ring structures (hexameric aggregates) believed to represent transmembrane pores, which are permeable to ions and small metabolites. It has a marked preference for rabbit red blood cells. α-hemolysin stimulates cellular phospholipases and induces a Ca2+influx. It leads to membrane disruption of the endothelial barrier and leakage of cytoplasmic components and osmotic lysis of the cells. α-hemolysin is implicated in the pathogenesis of sepsis.
ALPHA-HEMOLYSIN Preparation Products And Raw materials
Raw materials
Preparation Products
ALPHA-HEMOLYSIN Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
| Shandong Xiya Chemical Co., Ltd. | 4009903999 13395398332 | sales@xiyashiji.com | China | 20788 | 60 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19935 | 58 |
| Shanghai Kanglang Biotechnology Co., Ltd. | 021-61998208 18217752821; | sales@klbio.cn | China | 9619 | 58 |
| Shanghai Zeye Biotechnology Co., Ltd. | 021-57896695 13122526631 | 2885575445@qq.com | China | 9777 | 58 |
| Shanghai Fusheng Industrial Co., LTD | 021-52961053 13524666654 | 3004902811@qq.com | China | 9724 | 58 |
| Shanghai Sig Biotechnology Co., LTD | 021-57810052 18930344717 | 2089316240@qq.com | China | 9390 | 58 |
| Hubei Kele Fine Chemical Co., Ltd | 027-59101668 19945030958 | 2223443625@qq.com | China | 7996 | 58 |
| Shanghai Yaji Biological Technology Co., Ltd. | 021-34661275 15301693058 | yajikit@163.com | China | 9925 | 58 |
| JiangSu Star Science Co.,Ltd | 400-605-7200 15335295587 | 3941881028@qq.com | China | 3755 | 58 |
