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3-Bromoanisole

3-Bromoanisole Structure
3-Bromoanisole structure
CAS No.
2398-37-0
Chemical Name:
3-Bromoanisole
Synonyms
1-BROMO-3-METHOXYBENZENE;META BROMO ANISOLE;M-BROMOANISOLE;3-Methoxybromobenzene;3-Methoxyphenyl bromide;M-Bro;NSC 82293;3-BROMOANISOLE;3-BROMO ANISOL;5-bromoanisole
CBNumber:
CB4384971
Molecular Formula:
C7H7BrO
Molecular Weight:
187.03
MDL Number:
MFCD00000081
MOL File:
2398-37-0.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:45
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3-Bromoanisole Properties

Melting point 2 °C
Boiling point 210-211 °C(lit.)
Density 1.490 g/mL at 20 °C
vapor pressure 38.39Pa at 25℃
refractive index n20/D 1.563(lit.)
Flash point 200 °F
storage temp. Sealed in dry,Room Temperature
solubility DMSO (Sparingly), Methanol (Slightly)
form Liquid
Specific Gravity 1.477
color Clear colorless to slightly yellow-brown
PH 5.5 (H2O, 20℃)
Water Solubility Miscible in methanol, benzene, hexane, toluene and dichloromethane. Practically insoluble in water.
BRN 1524687
Stability Stable. Combustible. Incompatible with strong oxidising agents, strong acids reducing agents.
InChIKey PLDWAJLZAAHOGG-UHFFFAOYSA-N
LogP 3.03
CAS DataBase Reference 2398-37-0(CAS DataBase Reference)
FDA UNII 7ZO6TY38WY
NIST Chemistry Reference Benzene, 1-bromo-3-methoxy-(2398-37-0)
EPA Substance Registry System m-Bromoanisole (2398-37-0)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H412
Precautionary statements  P273
Hazard Codes  Xi
Safety Statements  23-24/25
WGK Germany  3
F  8
Hazard Note  Irritant
TSCA  T
HS Code  29093038
NFPA 704
1
0 0

3-Bromoanisole price More Price(33)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich B56498 3-Bromoanisole ≥98% 2398-37-0 25g $56.5 2025-07-31 Buy
Sigma-Aldrich B56498 3-Bromoanisole ≥98% 2398-37-0 100g $134 2025-07-31 Buy
TCI Chemical B0545 3-Bromoanisole >98.0%(GC) 2398-37-0 25g $33 2025-07-31 Buy
TCI Chemical B0545 3-Bromoanisole >98.0%(GC) 2398-37-0 250g $101 2025-07-31 Buy
TRC B680120 3-Bromoanisole 2398-37-0 50g $85 2021-12-16 Buy
Product number Packaging Price Buy
B56498 25g $56.5 Buy
B56498 100g $134 Buy
B0545 25g $33 Buy
B0545 250g $101 Buy
B680120 50g $85 Buy

3-Bromoanisole Chemical Properties,Uses,Production

Chemical Properties

3-Bromoanisole, also known as m-Bromoanisole, is a clear colorless to pale yellow oily liquid. The boiling point is 210-211°C (100kPa), 105°C (2.13kPa), the relative density is 1.477, the refractive index is 1.5635, and the flash point is 93°C. It is soluble in alcohol, ether, benzene, and carbon disulfide, but insoluble in water. It is commonly used as a raw material for organic synthesis.

Uses

3-Bromoanisole used in chemical reaction as intermediates to obtain target materials such as dyes, pharmaceuticals, perfumes, photoinitiators and agrochemicals.

Preparation

3-Bromoanisole is synthesized through a reaction between m-bromophenol and dimethyl sulfate. The synthesis method involves the following steps:
Dissolve m-bromophenol in a sodium hydroxide solution.
Slowly add dimethyl sulfate dropwise to the solution while stirring.
Heat the mixture and allow it to react for 1 hour.
Cool the reaction mixture to separate the colorless oil formed.
Extract the water layer with ether.
Dry the ether extract and then distill it to recover the ether.
Distill the residue obtained after recovering the ether, along with the colorless oil, under reduced pressure.
This distillation process results in the production of m-bromoanisole as the final product.
The overall yield of m-bromoanisole achieved through this process is 90%.

Synthesis

Iodonium, (3-methoxyphenyl)(2,4,6-trimethylphenyl)-, 1,1,1-trifluoromethanesulfonate (1:1)

1464149-60-7

3-Bromoanisole

2398-37-0

GENERAL METHOD: A mixture of diaryliodonium salt (0.5 mmol), methylene halide (0.75 mmol) and acetonitrile (1 mL) was placed in a 10 mL reaction tube and heated at 80°C for 2 hours with vigorous stirring. After completion of the reaction (monitored by TLC or GC), the reaction mixture was cooled to room temperature and 5 mL of water was added. The mixture was stirred for 10 min and the product was extracted with ethyl acetate (3 x 10 mL). The organic layer was washed with water and dried with anhydrous sodium sulfate. The solvent was evaporated under reduced pressure to give the crude product. The crude product was purified by silica gel column chromatography with petroleum ether and ethyl acetate as eluents to give the pure m-bromoanisole. The structure of the product was confirmed by 1H NMR and 13C NMR analysis.

References

Application of Anisole, 2-Bromoanisole and 3-Bromoanisole as Overcharge Protection Additives in Lithium-Ion Batteries DOI:10.6023/A12110964
S. Ramalingam; S. Periandy. Spectroscopic investigation, computed IR intensity, Raman activity and vibrational frequency analysis on 3-bromoanisole using HF and DFT (LSDA/MPW1PW91) calculations. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 2011, 78 (2), 835-843. DOI:10.1016/j.saa.2010.12.043
Bobby Glover; Kimberly A. Harvey; Bing Liu; Matthew J. Sharp; and Maria F. Tymoschenko. Regioselective Palladium-Catalyzed Arylation of 3-Carboalkoxy Furan and Thiophene. Org. Lett. 2003, 5 (3), 301-304. DOI:10.1021/ol027266q

3-Bromoanisole Preparation Products And Raw materials

Raw materials

Sodium bromate Benzene Hydrogen Bromine Methanol
Sulfuric acid 3-Bromophenol Iodonium, (3-methoxyphenyl)(2,4,6-trimethylphenyl)-, 1,1,1-trifluoromethanesulfonate (1:1) Acetonitrile Cuprous bromide

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Preparation Products

Tramadol hydrochloride 3-Methoxyphenylboronic acid 2-Chloro-5-methoxyphenylboronic acid Tramadol ETHYL 3-METHOXYPHENYLACETATE
2-(3-METHOXYPHENYL)CYCLOHEXANONE 3-Methoxybenzoylacetonitrile 3-PHENOXYPHENOL Bromobenzene 3'-METHOXY-2,2,2-TRIFLUOROACETOPHENONE
3-(3-METHOXY-PHENYL)-THIOPHENE 1-(3-METHOXYPHENYL)CYCLOHEXANOL

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3-Bromoanisole Suppliers

Global( 684)Suppliers
Supplier Tel Email Country ProdList Advantage
Beijing Wisdom Chemicals Co., Ltd.
+8613701363759 market@wisdomchem.com China 254 58
Hebei Chuanghai Biotechnology Co., Ltd 		+8617732866630 abby@chuanghaibio.com China 8773 58
Hebei Mujin Biotechnology Co.,Ltd 		+8613288715578 sales@hbmojin.com China 12248 58
Hebei Chuanghai Biotechnology Co,.LTD 		+86-13131129325 sales1@chuanghaibio.com China 5251 58
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD 		+86-15350851019; +8615350851019 admin@86-ss.com China 999 58
Capot Chemical Co.,Ltd. 		+8613336195806 sales@capot.com China 29734 60
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21620 55
Shanghai Time Chemicals CO., Ltd. 		+86-021-57951555 +8617317452075 jack.li@time-chemicals.com China 1803 55
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29852 58
NINGBO INNO PHARMCHEM CO., LTD. 		13867897135 sales@nbinno.com CHINA 923 58
Supplier Advantage
Beijing Wisdom Chemicals Co., Ltd.
58
Hebei Chuanghai Biotechnology Co., Ltd 		58
Hebei Mujin Biotechnology Co.,Ltd 		58
Hebei Chuanghai Biotechnology Co,.LTD 		58
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD 		58
Capot Chemical Co.,Ltd. 		60
Henan Tianfu Chemical Co.,Ltd. 		55
Shanghai Time Chemicals CO., Ltd. 		55
career henan chemical co 		58
NINGBO INNO PHARMCHEM CO., LTD. 		58

Related articles

View Lastest Price from 3-Bromoanisole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-Bromoanisole pictures 2025-10-07 3-Bromoanisole
2398-37-0
 0.99 RongNa Biotechnology Co.,Ltd
3-Bromoanisole pictures 2025-09-23 3-Bromoanisole
2398-37-0
 US $99.00-66.00 / kg 0.00100000kg 99% 5000 HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
3-Bromoanisole pictures 2025-09-23 3-Bromoanisole
2398-37-0
 US $999.00-666.00 / ton 1ton 99% 5000 HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
  • 3-Bromoanisole pictures
  • 3-Bromoanisole
    2398-37-0
  • US $99.00-66.00 / kg
  • 99%
  • HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
  • 3-Bromoanisole pictures
  • 3-Bromoanisole
    2398-37-0
  • US $999.00-666.00 / ton
  • 99%
  • HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD

3-Bromoanisole Spectrum

3-Bromoanisole(2398-37-0)MS3-Bromoanisole(2398-37-0)1HNMR3-Bromoanisole(2398-37-0)13CNMR3-Bromoanisole(2398-37-0)IR13-Bromoanisole(2398-37-0)IR23-Bromoanisole(2398-37-0)Raman

2398-37-0(3-Bromoanisole)Related Search:

1,2-Dibromobenzene 2-Bromobenzonitrile 3-Bromobenzonitrile 3-Bromofluorobenzene 3-(Trifluoromethoxy)bromobenzene
3-Bromobenzyl alcohol 3-Nitrobenzyl bromide (3-NITROPHENYL)ACETIC ACID METHYL ESTER 3-Nitroacetophenone 3-Bromobenzyl bromide
3-Nitrobenzaldehyde 1-Bromo-3-iodobenzene 3-Bromobenzaldehyde 3-Bromobenzoic acid 1,3-Dibromobenzene
Bromine 2-BROMO-4,5-METHYLENEDIOXYCINNAMIC ACID 1-Bromo-3,4,5-trimethoxybenzene

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M-BROMOANISOLE META BROMO ANISOLE 5-bromoanisole 3-BROMO ANISOL 3-BROMOANISOLE TIMTEC-BB SBB007886 BROMOANISOLE(3-) 1-BROMO-3-METHOXYBENZENE 3-Methoxy-1-bromobenzene 3-Methoxybromobenzene 3-Methoxyphenyl bromide Anisole, m-bromo- m-Anisyl bromide m-Bromomethoxybenzene m-Bromophenyl methyl ether 1-bromo-3-methoxy-benzen 1-Bromo-3-methoxybenzene, 3-Bromophenyl methyl ether BroMobenzene between Methyl ether M-BROMO ANISOLE (3-BROMO ANISOLE) 3-Bromoanisole≥ 99.5% (GC) m-bromonisole(3-bromoanisole) M-Bromoanisole (3-Bromoanisole) 99.5% m-BROMOANISOLE pure 3-Bromoanisole,1-Bromo-3-methoxybenzene m-Bromoanisole 1g [2398-37-0] 3-BromoanisoleDISC 05/08/02 m-bromoanisole(MBA) 3-BROMOANISOLE, 98+% 3-Bromoanisole99% 3-BROMO ANISOLE FOR SYNTHESIS NSC 82293 Benzene, 1-bromo-3-methoxy- m-Bromophenyl methyl ethe m-Bromophenylmethylether m-Methoxybromobenzene m-Methoxyphenyl bromide m-Bromoanisoles 3-BroMoanisole, 99+% 100ML 3-BroMoanisole, 99+% 25ML M-Bro 3-Bromoanisole > 3-Bromoanisole ISO 9001：2015 REACH Meta Bromo Anisole (3-Bromo Anisole) Meta Bromo Anisole (MBA) 3-Bromoanisole pure, 98% 1-Bromo-3-Methoxybenzene 3-Bromoanisole M-bromophenyl ether 3-Bromoanisole 98% For Synthesis 3-Bromoanisol in isopropanol Meta bromobenzyl ether Phloroglucinol Impurity 242 2398-37-0 2938-37-0 2398-38-0 ARYL HALIDE Ethers Organic Building Blocks Oxygen Compounds