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2'-Methoxyacetophenone

CAS No.
579-74-8
Chemical Name:
2'-Methoxyacetophenone
Synonyms
1-(2-methoxyphenyl)ethan-1-one;O-METHOXYACETOPHENONE;1-(2-METHOXYPHENYL)ETHANONE;O-ACETANISOLE;2-ACETANISOLE;2-[2-(4’2-ACETOANISOLE;2-ACETYLANISOLE;O-ACETYLANISOLE;ORTHO-ACETANISOLE
CBNumber:
CB4393230
Molecular Formula:
C9H10O2
Molecular Weight:
150.17
MDL Number:
MFCD00008725
MOL File:
579-74-8.mol
Last updated:2025-12-31 16:09:46
Product description Number Pack Size Price
2′-Methoxyacetophenone 99% M9203 25g $116
2′-Methoxyacetophenone 99% M9203 100g $262
2'-Methoxyacetophenone >97.0%(GC) M1445 25g $87
2'-Methoxyacetophenone >97.0%(GC) M1445 250g $734
2''-Methoxyacetophenone M261810 25g $75
More product size

2'-Methoxyacetophenone Properties

Melting point 117–119°C
Boiling point 131 °C18 mm Hg(lit.)
Density 1.09 g/mL at 25 °C(lit.)
FEMA 4163 | 2-METHOXYACETOPHENONE
refractive index n20/D 1.5393(lit.)
Flash point 228 °F
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Chloroform (Sparingly), Methanol (Sparingly)
form Liquid
color Clear slightly yellow to orange or slightly brown
Odor at 1.00 % in propylene glycol. powdery anisic almond phenolic
Odor Type anisic
Water Solubility immiscible
Sensitive Light Sensitive
JECFA Number 2042
BRN 1100602
LogP 1.82
CAS DataBase Reference 579-74-8(CAS DataBase Reference)
Substances Added to Food (formerly EAFUS) 2-METHOXYACETOPHENONE
FDA UNII 0WYN389I4N
NIST Chemistry Reference Ortho-methoxyacetophenone(579-74-8)
EPA Substance Registry System Ethanone, 1-(2-methoxyphenyl)- (579-74-8)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P501
Hazard Codes  Xn,Xi
Risk Statements  22-36/38-36/37/38
Safety Statements  37/39-26-36
WGK Germany  3
TSCA  TSCA listed
HS Code  29145000
NFPA 704
1
2 0

2'-Methoxyacetophenone price More Price(31)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich M9203 2′-Methoxyacetophenone 99% 579-74-8 25g $116 2025-07-31 Buy
Sigma-Aldrich M9203 2′-Methoxyacetophenone 99% 579-74-8 100g $262 2025-07-31 Buy
TCI Chemical M1445 2'-Methoxyacetophenone >97.0%(GC) 579-74-8 25g $87 2025-07-31 Buy
TCI Chemical M1445 2'-Methoxyacetophenone >97.0%(GC) 579-74-8 250g $734 2025-07-31 Buy
TRC M261810 2''-Methoxyacetophenone 579-74-8 25g $75 2021-12-16 Buy
Product number Packaging Price Buy
M9203 25g $116 Buy
M9203 100g $262 Buy
M1445 25g $87 Buy
M1445 250g $734 Buy
M261810 25g $75 Buy

2'-Methoxyacetophenone Chemical Properties,Uses,Production

Chemical Properties

clear slightly yellow to orange or slightly

Chemical Properties

Colorless to pale yellow clear liquid; powdery anisic almond phenolic aroma.

Uses

2''-Methoxyacetophenone is a useful building block, often used in the preparation of chalcones, such as the chalcones of 3-benzylidene-2-chlorocyclohex-1-enecarbaldehyde for use as potential anti-proliferative agents.

Preparation

Preparation by reaction of dimethyl sulfate with o-hydroxyacetophenone in the presence of sodium hydroxide.

Aroma threshold values

Anisic-type, medium strength odor; recommend smelling in a 1.00% solution or less.

Taste threshold values

Powdery musty anisic almond taste at 30 ppm in water.

Synthesis Reference(s)

Tetrahedron Letters, 22, p. 2605, 1981 DOI: 10.1016/S0040-4039(01)90532-5
Journal of the American Chemical Society, 72, p. 5161, 1950 DOI: 10.1021/ja01167a100
The Journal of Organic Chemistry, 52, p. 150, 1987 DOI: 10.1021/jo00377a027

118-93-4
77-78-1
579-74-8
Synthesis of 2'-Methoxyacetophenone from 2'-Hydroxyacetophenone and Dimethyl sulfate
Global( 304)Suppliers
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View Lastest Price from 2'-Methoxyacetophenone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2'-Methoxyacetophenone pictures 2025-05-26 2'-Methoxyacetophenone
579-74-8
US $5.00-2.00 / KG 1KG 99% 10000kg Hebei Chuanghai Biotechnology Co,.LTD
2'-Methoxyacetophenone pictures 2019-07-06 2'-Methoxyacetophenone
579-74-8
US $1.00 / KG 1G 98% 100KG Career Henan Chemical Co
AKOS BBS-00003280 2-ACETYLANISOLE 2-ACETOANISOLE 2-ACETANISOLE JR-8523, 1-(2-Methoxyphenyl)ethanone, 97% -Chloro-biphenyl-4-yl)-2-oxo-ethyl]acrylic acid 1-(2-METHOXYPHENYL)ETHANONE O-METHOXYACETOPHENONE O-ACETANISOLE O-ACETYLANISOLE ORTHO-ACETANISOLE 2Methoxyacetophenone99% 1-Acetyl-2-methoxybenzene Methyl(2-methoxyphenyl) ketone 1-(2-methoxyphenyl)-ethanon 2-methoxyacetylbenzene Acetophenone, 2'-methoxy- Ethanone, 1-(2-methoxyphenyl)- -Methoxy acetophenone 1-(2-methoxyphenyl)ethan-1-one 2’-Methoxyacetophenone 99% 2-Methoxyacetophenone,2-Acetylanisole 2-Acetoanisole 2-Acetylanisole 2'-Methoxyacetophenone, 98%+ 2-[2-(4&rsquo 2'-Methoxyacetophenone> 2-Acetoanisole,>98% O-Methoxy acetophenone 99% 2-Methoxyphenyl methyl ketone 2'-Methoxyacetophenone, ≥ 97.0% 2'-Methoxyacetophenone 2'-Methoxyacetophenone, 95% 2′-Methoxyacetophenone, CAS 579-74-8 579-74-8 C9H10O2 KETONE Organic Building Blocks Ketones Building Blocks C9 Carbonyl Compounds Building Blocks C9 Carbonyl Compounds Chemical Synthesis Ketones Organic Building Blocks Aromatic Acetophenones & Derivatives (substituted)