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GAMMA-SECRETASE INHIBITOR

CAS No.
133407-83-7
Chemical Name:
GAMMA-SECRETASE INHIBITOR
Synonyms
IN1097;Z-LLNLE-CHO;Z-LEU-LEU-NLE-CHO;Z LLNle CHO,ZLLNleCHO;Z-LEU-LEU-NLE-ALDEHYDE;γ-Secretase Inhibitor I;γ–Secretase Inhibitor I;CBZ-Leu-Leu-Nle-Aldehyde;GAMMA-SECRETASE INHIBITOR;GAMMA-SECRETASE INHIBITOR I
CBNumber:
CB4394833
Molecular Formula:
C26H41N3O5
Molecular Weight:
475.62
MDL Number:
MFCD02179375
MOL File:
133407-83-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-11 16:31:51
Product description Number Pack Size Price
γ-Secretase Inhibitor I The γ-Secretase Inhibitor I controls the biological activity of γ-Secretase. This small molecule/inhibitor is primarily used for Neuroscience applications. 565750 1MG $189
Z-Leu-Leu-Nle-aldehyde 32788 5MG $312.27
Z-Leu-Leu-Nle-aldehyde 32788 25MG $1150.22
Z-LLNle-CHO BA3270 1mg $85
Z-LLNle-CHO BA3270 5mg $216
More product size

GAMMA-SECRETASE INHIBITOR Properties

storage temp. −20°C
solubility DMSO: soluble
form powder
color White to off-white
Sensitive Hygroscopic
UNSPSC Code 12352200
NACRES NA.54

SAFETY

Risk and Safety Statements

WGK Germany  3
Storage Class 11 - Combustible Solids

GAMMA-SECRETASE INHIBITOR price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 565750 γ-Secretase Inhibitor I The γ-Secretase Inhibitor I controls the biological activity of γ-Secretase. This small molecule/inhibitor is primarily used for Neuroscience applications. 1MG $189 2026-04-30 Buy
Chem-Impex 32788 Z-Leu-Leu-Nle-aldehyde 133407-83-7 5MG $312.27 2026-05-19 Buy
Chem-Impex 32788 Z-Leu-Leu-Nle-aldehyde 133407-83-7 25MG $1150.22 2026-05-19 Buy
ApexBio Technology BA3270 Z-LLNle-CHO 133407-83-7 1mg $85 2026-05-06 Buy
ApexBio Technology BA3270 Z-LLNle-CHO 133407-83-7 5mg $216 2026-05-06 Buy
Product number Packaging Price Buy
565750 1MG $189 Buy
32788 5MG $312.27 Buy
32788 25MG $1150.22 Buy
BA3270 1mg $85 Buy
BA3270 5mg $216 Buy

GAMMA-SECRETASE INHIBITOR Chemical Properties,Uses,Production

Uses

gamma-Secretase Inhibitor I is a γ-secretase inhibitor.

Biological Activity

Cell permeable: yes', 'Primary Target
γ-secretase', 'Product does not compete with ATP.', 'Reversible: no

in vivo

Z-LLNle-CHO (5 mg/kg; s.c.; single daily for 12 days) inhibits engraftment of B-lymphoblasts in precursor-B ALL xenograft model[2].

Animal Model:Female SCID/NOD mice (6-8-week-old; precursor-B ALL xenograft model)[2].
Dosage:5 mg/kg
Administration:Subcutaneous injection; single daily for 12 days
Result:Delayed or prevented engraftment of B-lymphoblasts in 50% of the animals comprising the experimental group.

GAMMA-SECRETASE INHIBITOR Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 74)Suppliers
Supplier Tel Email Country ProdList Advantage
Shenzhen Nexconn Pharmatechs Ltd
+86-755-89396905 +86-15013857715 admin@nexconn.com China 10404 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19553 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49979 58
Career Henan Chemica Co
+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30225 58
Nextpeptide Inc
+86-0571-81612335 +8613336028439 sales@nextpeptide.com China 19908 58
TargetMol Chemicals Inc.
+1-781-999-5354; support@targetmol.com United States 39040 58
Nanjing TGpeptide
+86-13347807150 support@tgpeptide.com China 3279 58
Aladdin Scientific
tp@aladdinsci.com United States 57505 58
TargetMol Chemicals Inc.
+17819995354 marketing@targetmol.com United States 19957 58
Changsha MOL Changes Biotechnology Co., Ltd.
+8619375158599 info@molchanges.com China 5218 58

View Lastest Price from GAMMA-SECRETASE INHIBITOR manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Z-LLNle-CHO pictures 2026-05-11 Z-LLNle-CHO
133407-83-7
US $2500.00-1980.00 / mg 10g TargetMol Chemicals Inc.
  • Z-LLNle-CHO pictures
  • Z-LLNle-CHO
    133407-83-7
  • US $2500.00-1980.00 / mg
  • TargetMol Chemicals Inc.
Z-LEU-LEU-NLE-ALDEHYDE Z-LEU-LEU-NLE-CHO Z-LLNLE-CHO GAMMA-SECRETASE INHIBITOR GAMMA-SECRETASE INHIBITOR I Cbz-leucinyl-leucinyl-norleucinal γ-Secretase Inhibitor I L-Leucinamide, N-[(phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-1-formylpentyl]- benzyl N-[4-methyl-1-[[4-methyl-1-oxo-1-(1-oxohexan-2-ylamino)pentan-2-yl]amino]-1-oxopentan-2-yl]carbamate CBZ-Leu-Leu-Nle-Aldehyde Z LLNle CHO,ZLLNleCHO Benzyl ((S)-4-methyl-1-(((S)-4-methyl-1-oxo-1-(((S)-1-oxohexan-2-yl)amino)pentan-2-yl)amino)-1-oxopentan-2-yl)carbamate γ–Secretase Inhibitor I IN1097 133407-83-7 C33H57F2N5O9 Biochemicals and Reagents BioChemical R to Z gamma Secretase Enzyme Inhibitors Enzymes, Inhibitors, and Substrates Enzyme Inhibitors by Enzyme Alzheimers and Neurodegenerative Disease Research gamma SecretaseNeurobiology Neurodegenerative Disease Peptides Other Alzheimer Peptides Protease Inhibitor Specificity Index Protease Inhibitors R to γSecretaseEnzyme Inhibitors by Enzyme OtherNeuropeptides Z-Leu-Leu-Nle-CHO Pepetides peptides