PRLX93936 rastin analogue
- CAS No.
- 903499-49-0
- Chemical Name:
- PRLX93936 rastin analogue
- Synonyms
- PRLX-93936;PRLX93936,PRLX 93936;PRLX93936 rastin analogue;3-(2-ethoxyphenyl)-2-(1-piperazinylmethyl)-4(3H)-quinazolinone;4(3H)-Quinazolinone, 3-(2-ethoxyphenyl)-2-(1-piperazinylmethyl)-;3-(2-Ethoxyphenyl)-2-(piperazin-1-ylmethyl)quinazolin-4(3H)-one , PRLX-93936
- CBNumber:
- CB44201083
- Molecular Formula:
- C21H24N4O2
- Molecular Weight:
- 364.44
- MDL Number:
- MFCD18633228
- MOL File:
- 903499-49-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 545.5±60.0 °C(Predicted) |
|---|---|
| Density | 1.25±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO: Soluble |
| form | A solid |
| pka | 9.01±0.10(Predicted) |
| FDA UNII | E6999JX933 |
PRLX93936 rastin analogue price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 25631 | PRLX-93936 ≥98% | 903499-49-0 | 1mg | $63 | 2026-04-30 | Buy |
| Cayman Chemical | 25631 | PRLX-93936 ≥98% | 903499-49-0 | 5mg | $257 | 2026-04-30 | Buy |
| Cayman Chemical | 25631 | PRLX-93936 ≥98% | 903499-49-0 | 10mg | $454 | 2026-04-30 | Buy |
| Cayman Chemical | 25631 | PRLX-93936 ≥98% | 903499-49-0 | 25mg | $976 | 2026-04-30 | Buy |
| ChemScene | CS-0077444 | PRLX-93936 98.31% | 903499-49-0 | 1mg | $182 | 2026-06-04 | Buy |
PRLX93936 rastin analogue Chemical Properties, Uses, Production
Uses
PRLX-93936 dihydrochloride (Compound 16) is a HIF-1α inhibitor with anticancer activity. PRLX-93936 can inhibit the activated Ras pathway and can be used in the study of relapsed or refractory multiple myeloma[1][2].
References
[1] Huang W, et al. Synthesis and evaluation of quinazolin-4-ones as hypoxia-inducible factor-1α inhibitors. Bioorg Med Chem Lett. 2011 Sep 15;21(18):5239-43. DOI:10.1016/j.bmcl.2011.07.043
[2] Voorhees P M, et al. An open-label, dose escalation, multi-center phase 1 study of PRLX 93936, an agent synthetically active against the activated ras pathway, in the treatment of relapsed or relapsed and refractory multiple myeloma[J]. Blood, 2014, 124(21): 2140.
PRLX93936 rastin analogue Preparation Products And Raw materials
Raw materials
Preparation Products
PRLX93936 rastin analogue Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Beckham Medical Technology Co., Ltd | 13816613772 | huahero21@sina.com | China | 2996 | 55 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 400-920-5774 | sales@glpbio.cn | China | 6705 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Shanghai Dongyang Biotechnology Co., Ltd. | 0512-13601744364 13601744364 | chemsharker@126.com | China | 1161 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| Jinan Jiuli Biotechnology Co. , Ltd. | 15865264761 | 486064515@qq.com | China | 4999 | 58 |
| Beijing Biocreative Technology Co., Ltd. | 15522676233 | 3007606172@qq.com | China | 1246 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 5985 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
View Latest Price from PRLX93936 rastin analogue manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-17 | PRLX-93936
903499-49-0
|
$55.00-225.00 | 10g | TargetMol Chemicals Inc. |
-
- PRLX-93936
903499-49-0
- $55.00-225.00
- TargetMol Chemicals Inc.
