ChemicalBook >> CAS DataBase List >>N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE

N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE

N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE structure

CAS No.: 132172-61-3

Chemical Name:: N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE

Synonyms: DOTAP;DOTMA;dotap chloride;DOTAP-Cl;1,2-dioleoyl-3-trimethylammonium-propane (chloride salt);NSC8484;NSC 8484;NSC-8484;Lipofectin;18:1 TAP (DOTAP)

CBNumber:: CB4441795

Molecular Formula:: C42H80ClNO4

Molecular Weight:: 698.56

MDL Number:: MFCD01310872

MOL File:: 132172-61-3.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-07-27 11:17:52

Product description	Number	Pack Size	Price
DOTAP chloride ≥98% (TLC), powder	D6182	50mg	$507
DOTAP chloride ≥98% (TLC), powder	D6182	250mg	$2010
N-(2,3-Dioleoyloxy)propyl-N,N,N-trimethylammonium Chloride	D5916	250MG	$202
N-(2,3-Dioleoyloxy)propyl-N,N,N-trimethylammonium Chloride	D5916	1G	$503
1,2-Dioleoyl-3-trimethylammoniumpropane (chloride) ≥95%	15110	50mg	$61
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N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE Properties

Melting point	35-38°C
storage temp.	-20°C
solubility	Chloroform (Slightly)
form	lyophilized powder
color	White to Pale Yellow
Stability	Store in Freezer, Hygroscopic
Cosmetics Ingredients Functions	SKIN CONDITIONING
InChIKey	KSXTUUUQYQYKCR-LQDDAWAPSA-M
SMILES	C(C[N+](C)(C)C)(COC(=O)CCCCCCC/C=C\CCCCCCCC)OC(=O)CCCCCCC/C=C\CCCCCCCC.[Cl-]
FDA UNII	3R78UC794Z
UNSPSC Code	12352211
NACRES	NA.32

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS06,GHS08
Signal word	Danger
Hazard statements	H302-H315-H319-H331-H336-H351-H361d-H372-H412
Precautionary statements	P201-P273-P301+P312+P330-P302+P352-P304+P340+P311-P308+P313
PPE	Eyeshields, Gloves, type N95 (US)
WGK Germany	3
Storage Class	11 - Combustible Solids

N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE price More Price(58)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	D6182	DOTAP chloride ≥98% (TLC), powder	132172-61-3	50mg	$507	2026-04-30	Buy
Sigma-Aldrich	D6182	DOTAP chloride ≥98% (TLC), powder	132172-61-3	250mg	$2010	2026-04-30	Buy
TCI Chemical	D5916	N-(2,3-Dioleoyloxy)propyl-N,N,N-trimethylammonium Chloride	132172-61-3	250MG	$202	2026-04-30	Buy
TCI Chemical	D5916	N-(2,3-Dioleoyloxy)propyl-N,N,N-trimethylammonium Chloride	132172-61-3	1G	$503	2026-04-30	Buy
Cayman Chemical	15110	1,2-Dioleoyl-3-trimethylammoniumpropane (chloride) ≥95%	132172-61-3	50mg	$61	2026-04-30	Buy

Product number	Packaging	Price	Buy
D6182	50mg	$507	Buy
D6182	250mg	$2010	Buy
D5916	250MG	$202	Buy
D5916	1G	$503	Buy
15110	50mg	$61	Buy

N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE Chemical Properties,Uses,Production

Description

DOTAP chloride (1,2-Dioleoyl-3-trimethylammonium-propane chloride) is a potent cationic lipid widely used as a liposomal transfection reagent. DOTAP is also a strong activator of the innate immune system in animal cells and could serve as a potential candidate for the study of elicitors of plant immunity.

Description

DOTAP, 1,2-Dioleoyl-3-trimethylammonium propane is a di-chain, or gemini, cationic surfactant. DOTAP has been used for in vitro and in vivo nucleic acid and protein delivery.

Chemical Properties

White Foam

Uses

Small unilamellar liposomes containing DOTMA interact spontaneously with DNA to form lipid-DNA complexes with 100% entrapment of DNA. Facilitates fusion of the complex with the plasma membrane of tissue culture cells, resulting in both uptake and

Uses

1,2-dioleoyloxy-3-(trimethylammonium)propane (DOTAP) chloride has been used for the preparation of cationic liposome and liposome-DNA complex. It has also been used to assess tumor necrosis factor α (TNF- α) production.

Biochem/physiol Actions

18:1 TAP (DOTAP) is a cationic lipid structure, used for in vitro and in vivo nucleic acid and protein delivery. The lipid composition and cell type affects the transfection potential of DOTAP(1,2-dioleoyl-3-trimethylammonium-propane). 18:1 TAP (DOTAP) mediates gene knockdown technique in hematopoietic stem cells (HSCs).

N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE Suppliers

Global( 218)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Suzhou Highfine Biotech Co.,Ltd.	+86-0512-68071238 +86-13771819922	june@highfine.com	China	491	58
Aladdin Scientific		tp@aladdinsci.com	United States	54746	58
XIAMEN SINOPEG BIOTECH CO., LTD.	+86-0592-7761068 15616186207	changaiwei@sinopeg.com	China	1133	58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	+86-15225627621 +86-13213167925	jiuyitime@fdachem.com	China	16505	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21533	55
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19935	58
Zhengzhou Alfa Chemical Co.,Ltd	+86-18530059196	sale04@alfachem.cn	China	9666	58
TargetMol Chemicals Inc.	+1-781-999-5354; +1-00000000000	marketing@targetmol.com	United States	32431	58
Career Henan Chemica Co	+86-0371-86658258 +86-13203830695	laboratory@coreychem.com	China	30203	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 17705817739	info@dycnchem.com	China	52693	58

Supplier	Advantage
Suzhou Highfine Biotech Co.,Ltd.	58
Aladdin Scientific	58
XIAMEN SINOPEG BIOTECH CO., LTD.	58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	58
Henan Tianfu Chemical Co.,Ltd.	55
BOC Sciences	58
Zhengzhou Alfa Chemical Co.,Ltd	58
TargetMol Chemicals Inc.	58
Career Henan Chemica Co	58
Dayang Chem (Hangzhou) Co.,Ltd.	58

View Lastest Price from N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-08-25	DOTAP chloride 132172-61-3	$2.20-8.80	1kg	99%min	100kg	ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
2026-07-27	DOTAP chloride 132172-61-3	$31.00-81.00		99.96%	10g	TargetMol Chemicals Inc.
2026-07-27	DOTAP chloride 132172-61-3	$31.00-81.00		99.96%	10g	TargetMol Chemicals Inc.

DOTAP chloride
132172-61-3
$2.20-8.80
99%min
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

DOTAP chloride
132172-61-3
$31.00-81.00
99.96%
TargetMol Chemicals Inc.

DOTAP chloride
132172-61-3
$31.00-81.00
99.96%
TargetMol Chemicals Inc.

N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE Spectrum

N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE(132172-61-3)¹HNMR

132172-61-3(N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE)Related Search:

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DODMA Ammonium chloride DOTAP MESYLATE, 98 DOTAP N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE

DOTAP DOTAP DOTAP(OH)2 MESYLATE DOTAP MESYLATE DOTAP METHYL SULPHATE SALT

DOTAP DOTAP(OH) MESYLATE DOTAP acetate

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1,2-DIOLEOYL-3-TRIMETHYLAMMONIUM-PROPANE, CHLORIDE DOTAP CHLORIDE SALT N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE N-[1-(2,3-DIOLEOYLOXY)PROPYL]-N,N,N-TRIMETHYL-AMMONIUM CHLORIDE SALT N-[1-(2,3-DIOLEOYLOXY) PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE TRIMETHYL[2,3-(DIOLEYLOXY)PROPYL]AMMONIUM CHLORIDE 2,3-Bis(oleoyloxy)-N,N,N-trimethyl-1-propanaminium 3-(Trimethylaminio)propane-1,2-diol 1,2-bis[(Z)-9-octadecenoate] Lipofectin N-[2,3-Bis(oleoyloxy)propyl]-N,N-dimethylmethanaminium N-[2,3-Di(oleoyloxy)propyl]-N,N,N-trimethylaminium N,N,N-TriMethyl-2,3-bis[[(9Z)-1-oxo-9-octadecenyl]oxy]-1-propanaMiniuM DOTAP;DOTAP, CHLORIDE 18:1 TAP (DOTAP) 2,3-di(octadec-9-enoyloxy)propyl-trimethylazanium (2，3-Dioleyl-propyl) -trimethylamine N,N,N-Trimethyl-2,3-bis(oleoyloxy)propan-1-aminium chloride 1-Propanaminium, N,N,N-trimethyl-2,3-bis[[(9Z)-1-oxo-9-octadecenyl]oxy]-, chloride (1:1) NSC 8484 NSC8484 NSC-8484 N-(2,3-Dioleoyloxy)propyl-N,N,N-trimethylammonium Chloride DOTAP (chloride salt) (2,3-dioleoyl-propyl) - trimethylamine (chloride salt) DOTAP chloride, 10 mM in DMSO (2,3-dioxopropyl) trimethylammonium chloride N-[2,3-Di(Oleoyloxy)propyl]-N,N,N-trimethylaminium chloride DOTMA DOTAP 1,2-dioleoyl-3-trimethylammonium-propane (chloride salt) DOTAP-Cl dotap chloride 132172-61-3 C42H80ClNO4 C40H80ClNO2 C42H80NO4Cl Ammonium Chlorides (Quaternary) Quaternary Ammonium Compounds BioChemical Cloning and Expression Molecular Biology Transfection & Transformation Fatty Acid Derivatives & Lipids Glycerols Mixed Fatty Acids