5-METHYL-1H-INDOLE-3-CARBOXYLIC ACID
- CAS No.
- 10242-02-1
- Chemical Name:
- 5-METHYL-1H-INDOLE-3-CARBOXYLIC ACID
- Synonyms
- RARECHEM AL BE 0707;5-Methyl-3-indole acid;5-Methylindole-3-forMicacid;5-METHYLINDOLE-3-CARBOXYLIC ACID;5-METHYL-1H-INDOLE-3-CARBOXYLIC ACID;1H-Indole-3-carboxylic acid, 5-methyl-
- CBNumber:
- CB4444761
- Molecular Formula:
- C10H9NO2
- Molecular Weight:
- 175.18
- MDL Number:
- MFCD06203285
- MOL File:
- 10242-02-1.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
| HS Code | 2933998090 |
5-METHYL-1H-INDOLE-3-CARBOXYLIC ACID price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | M321273 | 5-Methyl-1H-indole-3-carboxylicacid | 10242-02-1 | 250mg | $55 | 2021-12-16 | Buy |
| Apolloscientific | OR913133 | 5-Methyl-1H-indole-3-carboxylicacid 98% | 10242-02-1 | 1g | $138 | 2021-12-16 | Buy |
| AK Scientific | X8614 | 5-Methyl-1H-indole-3-carboxylicacid | 10242-02-1 | 10g | $357 | 2021-12-16 | Buy |
| Apolloscientific | OR913133 | 5-Methyl-1H-indole-3-carboxylicacid 98% | 10242-02-1 | 5g | $363 | 2021-12-16 | Buy |
| Apolloscientific | OR913133 | 5-Methyl-1H-indole-3-carboxylicacid 98% | 10242-02-1 | 10g | $580 | 2021-12-16 | Buy |
5-METHYL-1H-INDOLE-3-CARBOXYLIC ACID Chemical Properties,Uses,Production
Synthesis
124-38-9
614-96-0
10242-02-1
Lithium tert-butoxide (LiOtBu, 160 mg, 2.00 mmol) and 5-methylindole (23.4 mg, 0.4 mmol) were added to a dry two-necked reaction vessel. The reaction vessel was evacuated by placing it under high vacuum conditions, followed by the passage of carbon dioxide gas (CO2 balloon). After addition of N,N-dimethylformamide (DMF, 2 mL), the reaction mixture was stirred at 100 °C for 24 hours. After completion of the reaction, the mixture was cooled to room temperature and the reaction was carefully quenched with 2N hydrochloric acid (HCl) solution. The reaction mixture was extracted several times with ethyl acetate (EtOAc, 5 x 5 mL). The organic phases were combined, washed sequentially with water (2 × 5 mL) and saturated saline (1 × 5 mL), and dried over anhydrous magnesium sulfate (MgSO4). The dried organic phases were concentrated under reduced pressure and the resulting residue was purified by preparative thin layer chromatography (TLC, Spreading agent: hexane/acetone=1:1) to afford the target product 5-methyl-1H-indole-3-carboxylic acid (153.0 mg, 95% yield) as a white solid.
References
[1] Organic Letters, 2012, vol. 14, # 20, p. 5326 - 5329,4
[2] Heterocycles, 2015, vol. 90, # 2, p. 1196 - 1204
5-METHYL-1H-INDOLE-3-CARBOXYLIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +8613336195806 | sales@capot.com | China | 29734 | 60 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49975 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29800 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52846 | 58 |
| Alfa Chemistry | +1-5166625404; | Info@alfa-chemistry.com | United States | 20405 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178; | peter68@ptchemgroup.com | China | 35425 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49977 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 |
View Lastest Price from 5-METHYL-1H-INDOLE-3-CARBOXYLIC ACID manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-08 | 5-METHYL-1H-INDOLE-3-CARBOXYLIC ACID
10242-02-1
|
US $0.01 / KG | 1KG | 98%; 99% | 1kg；10kg; 25kg | Career Henan Chemical Co |
-
- 5-METHYL-1H-INDOLE-3-CARBOXYLIC ACID
10242-02-1
- US $0.01 / KG
- 98%; 99%
- Career Henan Chemical Co
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