3-HYDROXY-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER
- CAS No.
- 62733-99-7
- Chemical Name:
- 3-HYDROXY-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER
- Synonyms
- SPECS AJ-333/25006091;Methyl 3-hydroxypicolinate;3-HYDROXYPICOLINIC ACID METHYL ESTER;Methyl-3-Hydroxypyridine-2-Carboxlate;METHYL 3-HYDROXYPYRIDINE-2-CARBOXYLATE;3-hydroxy-2-pyridinecarboxylicacidmethylester;3-Hydroxy-pyrdine-2-carboxylic acid methyl ester;3-Hydroxy-pyridin-2-carboxylic acid methyl ester;3-HYDROXY-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER;methyl 3-hydroxypyridine-2-carboxylate - [M28681]
- CBNumber:
- CB4459158
- Molecular Formula:
- C7H7NO3
- Molecular Weight:
- 153.14
- MDL Number:
- MFCD00661311
- MOL File:
- 62733-99-7.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Methyl 3-Hydroxy-2-pyridinecarboxylate >98.0%(GC) | M2973 | 1g | $89 |
| Methyl 3-Hydroxy-2-pyridinecarboxylate >98.0%(GC) | M2973 | 5g | $310 |
| Methyl3-hydroxypicolinate | M323485 | 1g | $75 |
| Methyl 3-hydroxypicolinate | 455267 | 100mg | $305 |
| 3-HYDROXY-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER 95.00% | CHM0023646 | 2.5G | $1363.65 |
| More product size | |||
| Melting point | 75.0 to 79.0 °C |
|---|---|
| Boiling point | 340.6±22.0 °C(Predicted) |
| Density | 1.287±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| form | powder to crystal |
| pka | 4.45±0.10(Predicted) |
| color | White to Orange to Green |
| InChI | InChI=1S/C7H7NO3/c1-11-7(10)6-5(9)3-2-4-8-6/h2-4,9H,1H3 |
| InChIKey | MHKKUZDJUGIOBC-UHFFFAOYSA-N |
| SMILES | C1(C(OC)=O)=NC=CC=C1O |
3-HYDROXY-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER price More Price(30)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | M2973 | Methyl 3-Hydroxy-2-pyridinecarboxylate >98.0%(GC) | 62733-99-7 | 1g | $89 | 2025-07-31 | Buy |
| TCI Chemical | M2973 | Methyl 3-Hydroxy-2-pyridinecarboxylate >98.0%(GC) | 62733-99-7 | 5g | $310 | 2025-07-31 | Buy |
| TRC | M323485 | Methyl3-hydroxypicolinate | 62733-99-7 | 1g | $75 | 2021-12-16 | Buy |
| Usbiological | 455267 | Methyl 3-hydroxypicolinate | 62733-99-7 | 100mg | $305 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0023646 | 3-HYDROXY-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER 95.00% | 62733-99-7 | 2.5G | $1363.65 | 2021-12-16 | Buy |
3-HYDROXY-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER Chemical Properties,Uses,Production
Synthesis
67-56-1
874-24-8
62733-99-7
A suspension of methanol (150 mL, 0.5 M) of 3-hydroxy-2-pyridinecarboxylic acid (10 g, 72 mmol, 1 eq.) was slowly added dropwise to concentrated sulfuric acid (12 mL, 216 mmol, 3 eq.) at 0 °C. The reaction mixture was stirred under reflux conditions for 6 hours. Upon completion of the reaction, the mixture was cooled to room temperature and concentrated under reduced pressure. Subsequently, the pH was adjusted to 8.5 with saturated aqueous NaHCO3 and solid NaHCO3. The aqueous layer was extracted with EtOAc, and the combined organic layers were washed with brine, dried over MgSO4, and concentrated under reduced pressure to afford methyl 3-hydroxy-2-pyridinecarboxylate as a white solid (10.9 g, 99%). Thin layer chromatography (TLC) showed Rf = 0.3 (petroleum ether/EtOAc 1:1, v/v). Melting point was 74°C. 1H NMR (300 MHz, CDCl3): δ (ppm) = 4.06 (s, 3H), 7.34 (dd, J = 3.9,8.4 Hz, 1H), 7.38 (dd, J = 1.5,8.4 Hz, 1H), 8.38 (dd, J = 1.5,3.9 Hz, 1H), 10.64 (s, 1H). 13C NMR (75 MHz, CDCl3): δ= 53.2,126.3,129.8,130.2,141.6,158.9,169.9. mass spectra (ESI+): m/z (%): 154 (100) [M + H]+.
References
[1] Journal of Controlled Release, 2018, vol. 290, p. 102 - 111
[2] Tetrahedron, 2011, vol. 67, # 11, p. 2118 - 2124
[3] Patent: WO2018/5662, 2018, A1. Location in patent: Paragraph 0290
[4] Patent: EP3255042, 2017, A2. Location in patent: Paragraph 0180; 0181
[5] Patent: WO2014/121418, 2014, A1. Location in patent: Page/Page column 44
3-HYDROXY-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8753 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29735 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29833 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 9999 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10236 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
View Lastest Price from 3-HYDROXY-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-01-05 | 3-HYDROXY-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER
62733-99-7
|
US $10.00 / KG | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-11-18 | 3-HYDROXY-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER
62733-99-7
|
US $1.10 / g | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2024-04-25 | 3-HYDROXY-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER
62733-99-7
|
US $50.00 / kg | 1kg | 99.10% | 50000kg | Ouhuang Engineering Materials (Hubei) Co., Ltd |
-
- 3-HYDROXY-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER
62733-99-7
- US $10.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 3-HYDROXY-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER
62733-99-7
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
-
- 3-HYDROXY-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER
62733-99-7
- US $50.00 / kg
- 99.10%
- Ouhuang Engineering Materials (Hubei) Co., Ltd
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