Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>(E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine

(E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine

(E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine Structure
(E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine structure
CAS No.
1000672-89-8
Chemical Name:
(E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine
Synonyms
(E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine;2-[(1E)-2-(2-chlorophenyl)ethenyl]-3,5,6-trimethyl-pyrazine;Pyrazine, 2-[(1E)-2-(2-chlorophenyl)ethenyl]-3,5,6-trimethyl-
CBNumber:
CB44665601
Molecular Formula:
C15H15ClN2
Molecular Weight:
258.75
MDL Number:
MOL File:
1000672-89-8.mol
MSDS File:
SDS
Last updated:2026-04-21 10:31:43
Request For Quotation

(E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine Properties

storage temp. Store at -20°C
solubility DMF: 20 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 2 mg/ml; Ethanol: 2 mg/ml
form A crystalline solid

(E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 9003202 (E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine ≥98% 1000672-89-8 1mg $36 2026-04-30 Buy
Cayman Chemical 9003202 (E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine ≥98% 1000672-89-8 5mg $128 2026-04-30 Buy
Cayman Chemical 9003202 (E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine ≥98% 1000672-89-8 10mg $236 2026-04-30 Buy
Cayman Chemical 9003202 (E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine ≥98% 1000672-89-8 25mg $502 2026-04-30 Buy
aablocks AA01EQ5V (E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine ≥98% 1000672-89-8 1mg $36 2026-05-30 Buy
Product number Packaging Price Buy
9003202 1mg $36 Buy
9003202 5mg $128 Buy
9003202 10mg $236 Buy
9003202 25mg $502 Buy
AA01EQ5V 1mg $36 Buy

(E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine Chemical Properties, Uses, Production

Description

(E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine (CSTMP) is a stilbene derivative with antioxidant and anticancer activities.1,2,3 It stimulates proliferation of hydrogen peroxide-damaged ECV-304 cells (EC50 = 24.9 nM).1 CSTMP reduces hydrogen peroxide-induced release of lactate dehydrogenase (LDH) in and increases viability of human umbilical vein endothelial cells (HUVECs) in a concentration-dependent manner via inhibition of apoptosis.2 It reverses hydrogen peroxide-induced release of malondialdehyde (MDA) and decreases in superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) activities as well as increases constitutive nitric oxide synthase (cNOS) activity and nitric oxide (NO) production in HUVECs. CSTMP also induces cell death of A549 non-small cell lung cancer (NSCLC) cells in an IRE1α-dependent manner through induction of IRE1α-TRAF2-ASK1 complex-mediated endoplasmic reticulum (ER) stress and mitochondrial apoptosis.3

References

1. Deng, L., Guo, X., Zhai, L., et al. Ligustrazine derivatives. Part 4: Design, synthesis, and biological evaluation of novel ligustrazine-based stilbene derivatives as potential cardiovascular agents Chem. Biol. Drug Des. 79(5),731-739(2012).
2. Zhai, L., Zhang, P., Sun, R.-Y., et al. Cytoprotective effects of CSTMP, a novel stilbene derivative, against H2O2-induced oxidative stress in human endothelial cells Pharmacol. Rep. 63(6),1469-1480(2011).
3. Zhang, J., Liang, Y., Lin, Y., et al. IRE1α-TRAF2-ASK1 pathway is involved in CSTMP-induced apoptosis and ER stress in human non-small cell lung cancer A549 cells Biomed. Pharmacother. 82,281-289(2016).

(E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine Preparation Products And Raw materials

Raw materials

Preparation Products

(E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine Suppliers

Global Suppliers ( 10)
Supplier Tel Email Country ProdList Advantage
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Hangzhou MolCore BioPharmatech Co.,Ltd. +86-057181025280; +8617767106207 sales@molcore.com China 49709 58
Supplier Advantage
Shanghai Hongye Biotechnology Co. Ltd 58
TargetMol Chemicals Inc. 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 58

View Latest Price from (E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine pictures 2026-04-20 (E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine
1000672-89-8
 $113.00-775.00 10g TargetMol Chemicals Inc.

1000672-89-8 ((E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine) Related Search:

MAO-B-IN-39 Tannic acid thiola-cysteine disulfide DIDYMIN chikusetsu saponin IVa
(E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine Pyrazine, 2-[(1E)-2-(2-chlorophenyl)ethenyl]-3,5,6-trimethyl- 2-[(1E)-2-(2-chlorophenyl)ethenyl]-3,5,6-trimethyl-pyrazine 1000672-89-8