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ChemicalBook >> CAS DataBase List >>C6 Ceramide-d7 (d18:1-d7/6:0)

C6 Ceramide-d7 (d18:1-d7/6:0)

C6 Ceramide-d7 (d18:1-d7/6:0) Structure
C6 Ceramide-d7 (d18:1-d7/6:0) structure
CAS No.
2692624-22-7
Chemical Name:
C6 Ceramide-d7 (d18:1-d7/6:0)
Synonyms
C6 Ceramide-d7 (d18:1-d7/6:0)
CBNumber:
CB44666345
Molecular Formula:
C24H40D7NO3
Molecular Weight:
404.678012446
MDL Number:
MOL File:
2692624-22-7.mol
MSDS File:
SDS
Last updated:2026-05-28 01:54:33
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C6 Ceramide-d7 (d18:1-d7/6:0) Properties

solubility DMF: >22 mg/ml; DMSO: >20 mg/ml; Ethanol: >33 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml; PBS (pH 7.2): <50 μg/ml
form Liquid
color Colorless to light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Skull and Crossbones (GHS06)Health Hazard (GHS08)
GHS02,GHS06,GHS08
Signal word  Danger
Hazard statements  H225-H301+H311+H331-H370
Precautionary statements  P210-P240-P241-P242-P243-P260-P264-P270-P271-P280-P301+P310-P321-P330-P303+P361+P353-P304+P340-P307+P311-P312-P361+P364-P370+P378-P403+P233-P403+P235-P405-P501
NFPA 704
3
0 0

C6 Ceramide-d7 (d18:1-d7/6:0) price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 24826 C6 Ceramide-d7 (d18:1-d7/6:0) ≥99%deuteratedforms(d1-d7) 2692624-22-7 100μg $124 2026-04-30 Buy
Cayman Chemical 24826 C6 Ceramide-d7 (d18:1-d7/6:0) ≥99%deuteratedforms(d1-d7) 2692624-22-7 250μg $275 2026-04-30 Buy
Cayman Chemical 24826 C6 Ceramide-d7 (d18:1-d7/6:0) ≥99%deuteratedforms(d1-d7) 2692624-22-7 500μg $459 2026-04-30 Buy
Cayman Chemical 24826 C6 Ceramide-d7 (d18:1-d7/6:0) ≥99% deuterated forms (d1-d7) 2692624-22-7 100 μg $112 2024-03-01 Buy
Cayman Chemical 24826 C6 Ceramide-d7 (d18:1-d7/6:0) ≥99% deuterated forms (d1-d7) 2692624-22-7 250 μg $250 2024-03-01 Buy
Product number Packaging Price Buy
24826 100μg $124 Buy
24826 250μg $275 Buy
24826 500μg $459 Buy
24826 100 μg $112 Buy
24826 250 μg $250 Buy

C6 Ceramide-d7 (d18:1-d7/6:0) Chemical Properties, Uses, Production

Description

C6 Ceramide-d7 is intended for use as an internal standard for the quantification of short-chain ceramides, such as C2 ceramide , C6 ceramide , and C8 ceramide , by GC- or LC-MS. C6 Ceramide is a cell-permeable analog of naturally occurring ceramides. With a longer carbon chain than C2 ceramide, it is somewhat more hydrophobic, and may more closely mimic the effects of natural ceramides.1 C6 Ceramide mediates many diverse biological activities including apoptosis, activation of protein phosphatase 2A, and inhibition of the mitochondrial respiratory chain.1,2,3,4 It also enhances the expression of COX-2 in rat granulosa cells and stimulates the growth of bovine aortic smooth muscle cells.5,6 C6 Ceramide acts in neuronal axons to inhibit neurite growth.7

Uses

Ceramide C6-d7 is the deuterium labeled Ceramide C6. Ceramide C6, a Ceramide pathway activator, is an exogenous short-chain ceramide which can induce apoptosis of multiple cancer cells[1][2][3].

References

1. Dobrowsky, R.T., and Hannun, Y.A. Ceramide stimulates a cytosolic protein phosphatase J. Biol. Chem. 267(8),5048-5051(1992).
2. Cai, Z., Bettaieb, A., El Mahdani, N., et al. Alteration of the sphingomyelin/ceramide pathway is associated with resistance of human breast carcinoma MCF7 cells to tumor necrosis factor-α-mediated cytotoxicity J. Biol. Chem. 272(11),6918-6926(1997).
3. Dobrowsky, R.T., Kamibayashi, C., Mumby, M.C., et al. Ceramide activates heterotrimeric protein phosphatase 2A J. Biol. Chem. 268(21),15523-15530(1993).
4. Gudz, T.I., Tserng, K.Y., and Hoppel, C.L. Direct inhibition of mitochondrial respiratory chain complex III by cell-permeable ceramide J. Biol. Chem. 272(39),24154-24158(1997).
5. Santana, P., Llanes, L., Hernandez, I., et al. Interleukin-1β stimulates sphingomyelin hydrolysis in cultured granulosa cells: Evidence for a regulatory role of ceramide on progesterone and prostaglandin biosynthesis Endocrinology 137(6),2480-2489(1996).
6. Augé, N., Andrieu, N., Nègre-Salvayre, A., et al. The sphingomyelin-ceramide signaling pathway is involved in oxidized low density lipoprotein-induced cell proliferation J. Biol. Chem. 271(32),19251-19255(1996).
7. Posse de Chaves, E.I., Bussière, M., Vance, D.E., et al. Elevation of ceramide within distal neurites inhibits neurite growth in cultured rat sympathetic neurons J. Biol. Chem. 272(4),2038-3035(1997).

C6 Ceramide-d7 (d18:1-d7/6:0) Preparation Products And Raw materials

Raw materials

Preparation Products

C6 Ceramide-d7 (d18:1-d7/6:0) Suppliers

Global Suppliers ( 9)
Supplier Tel Email Country ProdList Advantage
Yichang Zhongyitai Trading Co., Ltd. 0717-6449896 13886658719 root@zhongyitai.com China 1978 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
CHINA ISOTOPE CO., LIMITED 02151600108 13062666369 info@isotopechem.com China 4721 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
Supplier Advantage
Yichang Zhongyitai Trading Co., Ltd. 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
CHINA ISOTOPE CO., LIMITED 58
Shanghai Yifei Biotechnology Co. , Ltd. 58

2692624-22-7 (C6 Ceramide-d7 (d18:1-d7/6:0)) Related Search:

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C6 Ceramide-d7 (d18:1-d7/6:0) 2692624-22-7