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APETx2

APETx2 structure

CAS No.: 713544-47-9

Chemical Name:: APETx2

Synonyms: APETx2;Cys6-Cys30;Cys20-Cys38);APETx2 USP/EP/BP;APETx2, ASIC3 channel blocker;APETx2, Anthopleura elegantissima, Recombinant, E. coli;H-Gly-Thr-Ala-Cys-Ser-Cys-Gly-Asn-Ser-Lys-Gly-Ile-Tyr-Trp-Phe-Tyr-Arg-Pro-Ser-Cys-Pro-Thr-Asp-Arg-Gly-Tyr-Thr-Gly-Ser-Cys-Arg-Tyr-Phe-Leu-Gly-Thr-Cys-Cys-Thr-Pro-Ala-Asp-OH(Disulfide bridge：Cys4-Cys37;2-[2-[[1-[2-[[52-[2-[[2-[(2-aminoacetyl)amino]-3-hydroxybutanoyl]amino]propanoylamino]-34-(4-aminobutyl)-40-(2-amino-2-oxoethyl)-19,69-dibenzyl-28-butan-2-yl-13,75,96-tris(3-carbamimidamidopropyl)-99-(carboxymethyl)-2~{a},60,87-tris(1-hydroxyethyl)-4,37,49,81-tetrakis(hydroxymethyl)-16,25,72,90-tetrakis[(4-hydroxyphenyl)methyl]-22-(1~{H}-indol-3-ylmethyl)-66-(2-methylpropyl)-1~{a},3,4~{a},6,10~{a},12,15,17~{a},18,21,24,27,30,33,36,39,42,45,48,51,59,62,65,68,71,74,77,80,83,86,89,92,95,98-tetratriacontaoxo-12~{a},13~{a},19~{a},20~{a},54,55-hexathia-~{a},2,3~{a},5,9~{a},11,14,16~{a},17,20,23,26,2

CBNumber:: CB44673963

Molecular Formula:: C196H280N54O61S6

Molecular Weight:: 0

MDL Number:

MOL File:: Mol file

TDS File:: TDS

Last updated:2026-04-24 14:58:35

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APETx2 Properties

storage temp.	Store at -20°C
solubility	aqueous buffer: soluble
form	Powder
Water Solubility	Soluble to 5 mg/ml in water
Sequence	Gly-Thr-Ala-Cys-Ser-Cys-Gly-Asn-Ser-Lys-Gly-Ile-Tyr-Trp-Phe-Tyr-Arg-Pro-Ser-Cys-Pro-Thr-Asp-Arg-Gly-Tyr-Thr-Gly-Ser-Cys-Arg-Tyr-Phe-Leu-Gly-Thr-Cys-Cys-Thr-Pro-Ala-Asp (Disulfide bridge:Cys4-Cys37;Cys6-Cys30;Cys20-Cys38)
UNSPSC Code	12352200

SAFETY

Risk and Safety Statements

WGK Germany	WGK 1
Storage Class	11 - Combustible Solids

APETx2 price More Price(6)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Usbiological	254652	APETx2 Asreported	713544-47-9	100ug	$644	2026-06-03	Buy
Biosynth	NDB54447	APETx2	713544-47-9	1mg	$6251.63	2026-06-04	Buy
Biosynth	APE-4472-S	APETx2	713544-47-9	0.1mg	$857.54	2026-06-04	Buy
ApexBio Technology	B5720	APETx2	713544-47-9	100ug	$852	2026-05-06	Buy
aablocks	AA01ENEA	APETx2 95%	713544-47-9	1mg	$781	2026-05-30	Buy

Product number	Packaging	Price	Buy
254652	100ug	$644	Buy
NDB54447	1mg	$6251.63	Buy
APE-4472-S	0.1mg	$857.54	Buy
B5720	100ug	$852	Buy
AA01ENEA	1mg	$781	Buy

APETx2 Chemical Properties, Uses, Production

Uses

APETx2 is a highly pure, synthetic and biologically active peptide toxin.

Biological Activity

APETx2, a sea anemone peptide from Anthopleura elegantissima, is a selective and reversible acid-sensing ion channel inhibitor of ASIC3 (acid-sensing ion channel) with IC50 of 63 nM. It acts outside the ASIC3 channel. APETx2 reverses acid-induced inflammatory pain.

in vitro

APETx2 (it or im application, 0.022 to 2.2 μM) resulted in a potent and complete reversal of established mechanical hypersensitivity in the complete Freund's adjuvant (CFA) inflammatory pain model.

storage

Store at -20°C

APETx2 Preparation Products And Raw materials

Raw materials

Preparation Products

APETx2 Suppliers

Global Suppliers ( 55)

Supplier	Tel	Email	Country	ProdList	Advantage
Creative Peptides		info@creative-peptides.com	United States	6083	56
Shanghai YuanYe Biotechnology Co., Ltd.	15026964105	2881489226@qq.com	China	89667	60
Hangzhou Peptidego Biotech Co.,Ltd.	0571-87213919 15967184799	Eric@peptidego.com	China	7872	58
Shenzhen Yuzhong Pharmaceutical Technology Co., Ltd.	13632427122;13414494621	chenchao02lzu@126.com	China	137	58
BOC Sciences	16314854226; +8616314854226	inquiry@bocsci.com	United States	19852	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471	sales@sarms4muscle.com	China	10378	58
Hangzhou Huarong Pharm Co., Ltd.	571-86758373 +8613588754946	sales@huarongpharm.com	CHINA	3147	58
Dideu Industries Group Limited	+8617392712697	1022@dideu.com	China	29090	58
Career Henan Chemica Co	+86-0371-86658258 +86-13203830695	laboratory@coreychem.com	China	30203	58
Wuxi Helen Biotechnology Co., Ltd.,	0510-85629785 18013409632	sales@reading-chemicals.com	China	14072	58

Supplier	Advantage
Creative Peptides	56
Shanghai YuanYe Biotechnology Co., Ltd.	60
Hangzhou Peptidego Biotech Co.,Ltd.	58
Shenzhen Yuzhong Pharmaceutical Technology Co., Ltd.	58
BOC Sciences	58
Zhejiang J&C Biological Technology Co.,Limited	58
Hangzhou Huarong Pharm Co., Ltd.	58
Dideu Industries Group Limited	58
Career Henan Chemica Co	58
Wuxi Helen Biotechnology Co., Ltd.,	58

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1of3

APETx2 2-[2-[[1-[2-[[52-[2-[[2-[(2-aminoacetyl)amino]-3-hydroxybutanoyl]amino]propanoylamino]-34-(4-aminobutyl)-40-(2-amino-2-oxoethyl)-19,69-dibenzyl-28-butan-2-yl-13,75,96-tris(3-carbamimidamidopropyl)-99-(carboxymethyl)-2~{a},60,87-tris(1-hydroxyethyl)-4,37,49,81-tetrakis(hydroxymethyl)-16,25,72,90-tetrakis[(4-hydroxyphenyl)methyl]-22-(1~{H}-indol-3-ylmethyl)-66-(2-methylpropyl)-1~{a},3,4~{a},6,10~{a},12,15,17~{a},18,21,24,27,30,33,36,39,42,45,48,51,59,62,65,68,71,74,77,80,83,86,89,92,95,98-tetratriacontaoxo-12~{a},13~{a},19~{a},20~{a},54,55-hexathia-~{a},2,3~{a},5,9~{a},11,14,16~{a},17,20,23,26,2 APETx2 USP/EP/BP Cys20-Cys38) Cys6-Cys30 H-Gly-Thr-Ala-Cys-Ser-Cys-Gly-Asn-Ser-Lys-Gly-Ile-Tyr-Trp-Phe-Tyr-Arg-Pro-Ser-Cys-Pro-Thr-Asp-Arg-Gly-Tyr-Thr-Gly-Ser-Cys-Arg-Tyr-Phe-Leu-Gly-Thr-Cys-Cys-Thr-Pro-Ala-Asp-OH(Disulfide bridge：Cys4-Cys37 APETx2, ASIC3 channel blocker APETx2, Anthopleura elegantissima, Recombinant, E. coli 713544-47-9 C196H280N54O61S6