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ChemicalBook >> CAS DataBase List >>7-AMINO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-BUTYL ESTER

7-AMINO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-BUTYL ESTER

7-AMINO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-BUTYL ESTER Structure
7-AMINO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-BUTYL ESTER structure
CAS No.
171049-41-5
Chemical Name:
7-AMINO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-BUTYL ESTER
Synonyms
7-AMINO-2-BOC-1,2,3,4-TETRAHYDROISOQUINOLINE;2-Boc-7-amino-1,2,3,4-tetrahydroisoquinoline;ethyl 7-amino-3,4-dihydroisoquinoline-2(1H)-carboxylate;TERT-BUTYL 7-AMINO-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE;tert-butyl 7-amino-3,4-dihydro-1H-isoquinoline-2-carboxylate;7-Amino-2-(tert-butoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline;7-AMINO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-B...;tert-butyl 7-aMino-1,2,3,4-tetrahydroisoquinoline-2-carboxylate;7-AMINO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-BUTYL ESTER;2(1H)-Isoquinolinecarboxylic acid, 7-amino-3,4-dihydro-, 1,1-dimethylethyl ester
CBNumber:
CB4468255
Molecular Formula:
C14H20N2O2
Molecular Weight:
248.32
MDL Number:
MFCD04973401
MOL File:
171049-41-5.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:44
Product description Number Pack Size Price
tert-Butyl7-Amino-3,4-dihydroisoquinoline-2(1H)-carboxylate B129595 100mg $60
tert-Butyl7-Amino-3,4-dihydroisoquinoline-2(1H)-carboxylate B129595 500mg $155
2-Boc-7-Amino-1,2,3,4-tetrahydroisoquinoline FB42011 250mg $200
2-Boc-7-Amino-1,2,3,4-tetrahydroisoquinoline W3728 5g $451
tert-Butyl 7-amino-3,4-dihydroisoquinoline-2(1H)-carboxylate 97% P000060255 10g $576
Request For Quotation

7-AMINO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-BUTYL ESTER Properties

Melting point 59-61 °C
Boiling point 394.7±42.0 °C(Predicted)
Density 1.145±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka 4.81±0.20(Predicted)
Appearance Light yellow to light brown Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338
Hazard Codes  Xn,N
Risk Statements  22-50
Safety Statements  61
RIDADR  UN2811

7-AMINO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-BUTYL ESTER price More Price(38)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC B129595 tert-Butyl7-Amino-3,4-dihydroisoquinoline-2(1H)-carboxylate 171049-41-5 100mg $60 2021-12-16 Buy
TRC B129595 tert-Butyl7-Amino-3,4-dihydroisoquinoline-2(1H)-carboxylate 171049-41-5 500mg $155 2021-12-16 Buy
Biosynth Carbosynth FB42011 2-Boc-7-Amino-1,2,3,4-tetrahydroisoquinoline 171049-41-5 250mg $200 2021-12-16 Buy
AK Scientific W3728 2-Boc-7-Amino-1,2,3,4-tetrahydroisoquinoline 171049-41-5 5g $451 2021-12-16 Buy
Ark Pharm P000060255 tert-Butyl 7-amino-3,4-dihydroisoquinoline-2(1H)-carboxylate 97% 171049-41-5 10g $576 2021-12-16 Buy
Product number Packaging Price Buy
B129595 100mg $60 Buy
B129595 500mg $155 Buy
FB42011 250mg $200 Buy
W3728 5g $451 Buy
P000060255 10g $576 Buy

7-AMINO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-BUTYL ESTER Chemical Properties,Uses,Production

Synthesis

tert-Butyl 7-nitro-3,4-dihydroisoquinoline-2(1H)-carboxylate

171049-42-6

7-AMINO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-BUTYL ESTER

171049-41-5

A mixed solution of 7-nitro-3,4-dihydroisoquinoline-2(1H)-carboxylic acid tert-butyl ester (33.2) (4.4 g, 15.81 mmol) was stirred with a mixed solution of Pd/C (500 mg, 4.69 mmol) in MeOH (100 mL) for 3 h at room temperature in an H2 atmosphere. Upon completion of the reaction, the reaction mixture was filtered to remove the catalyst. The filtrate was concentrated to afford the target product tert-butyl 7-amino-3,4-dihydroisoquinoline-2(1H)-carboxylate (33.3) as a yellow liquid (3.8 g, 96.8% yield). The product was characterized by 1H NMR (400 MHz, CDCl3): δ 1.48 (s, 9H), 2.71 (t, 2H), 3.58 (s, 4H), 4.47 (s, 2H), 6.44 (s, 1H), 6.52 (dd, 1H), 6.91 (d, 1H).

References

[1] Patent: WO2016/90079, 2016, A1. Location in patent: Paragraph 00538-00539
[2] Patent: WO2009/158426, 2009, A1. Location in patent: Page/Page column 108-109
[3] Patent: US2015/231142, 2015, A1. Location in patent: Paragraph 0670
[4] Patent: US2011/98311, 2011, A1

7-AMINO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-BUTYL ESTER Preparation Products And Raw materials

Raw materials

tert-Butyl 7-nitro-3,4-dihydroisoquinoline-2(1H)-carboxylate 1,2,3,4-TETRAHYDRO-ISOQUINOLIN-7-YLAMINE Di-tert-butyl dicarbonate Activated carbon Methanol
Hydrogen Palladium

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Preparation Products

7-AMINO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-BUTYL ESTER Suppliers

Global( 124)Suppliers
Supplier Tel Email Country ProdList Advantage
Accela ChemBio Inc. 		+1-858-6993322 info@accelachem.com United States 21193 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49977 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29795 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		+8613580539051 joe@yuhengpharm.com CHINA 21142 58
Finetech Industry Limited 		+86-27-8746-5837 +8619945049750 info@finetechnology-ind.com China 9629 58
Dayang Chem (Hangzhou) Co.,Ltd. 		+86-0571-88938639 +8617705817739 info@dycnchem.com China 52846 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418684 +8618949823763 sales@tnjchem.com China 25356 58
HANGZHOU LEAP CHEM CO., LTD. 		+86-571-87711850 market18@leapchem.com China 24597 58
PT CHEM GROUP LIMITED 		+86-85511178; peter68@ptchemgroup.com China 35425 58
Supplier Advantage
Accela ChemBio Inc. 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
career henan chemical co 		58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		58
Finetech Industry Limited 		58
Dayang Chem (Hangzhou) Co.,Ltd. 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
HANGZHOU LEAP CHEM CO., LTD. 		58
PT CHEM GROUP LIMITED 		58

View Lastest Price from 7-AMINO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-BUTYL ESTER manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
7-AMINO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-BUTYL ESTER pictures 2020-01-09 7-AMINO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-BUTYL ESTER
171049-41-5
 US $1.00 / KG 1KG 99% 200kg Career Henan Chemical Co

7-AMINO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-BUTYL ESTER Spectrum

7-AMINO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-BUTYL ESTER(171049-41-5)1HNMR

171049-41-5(7-AMINO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-BUTYL ESTER)Related Search:

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2-Boc-7-amino-1,2,3,4-tetrahydroisoquinoline TERT-BUTYL 7-AMINO-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE 7-AMINO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-BUTYL ESTER 7-AMINO-2-BOC-1,2,3,4-TETRAHYDROISOQUINOLINE tert-butyl 7-aMino-1,2,3,4-tetrahydroisoquinoline-2-carboxylate 7-Amino-2-(tert-butoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline ethyl 7-amino-3,4-dihydroisoquinoline-2(1H)-carboxylate 2(1H)-Isoquinolinecarboxylic acid, 7-amino-3,4-dihydro-, 1,1-dimethylethyl ester tert-butyl 7-amino-3,4-dihydro-1H-isoquinoline-2-carboxylate 7-AMINO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-B... 171049-41-5 pharmacetical